ID A0A2P7Z2D4_9PEZI Unreviewed; 1002 AA.
AC A0A2P7Z2D4;
DT 23-MAY-2018, integrated into UniProtKB/TrEMBL.
DT 23-MAY-2018, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=PH domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=B9Z65_4289 {ECO:0000313|EMBL:PSK42375.1};
OS Elsinoe australis.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Dothideomycetidae; Myriangiales; Elsinoaceae; Elsinoe.
OX NCBI_TaxID=40998 {ECO:0000313|EMBL:PSK42375.1, ECO:0000313|Proteomes:UP000243723};
RN [1] {ECO:0000313|EMBL:PSK42375.1, ECO:0000313|Proteomes:UP000243723}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NL1 {ECO:0000313|EMBL:PSK42375.1,
RC ECO:0000313|Proteomes:UP000243723};
RA Cheng Q.;
RT "Draft genome sequence of Elsinoe australis.";
RL Submitted (MAY-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the OSBP family.
CC {ECO:0000256|ARBA:ARBA00008842}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PSK42375.1}.
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DR EMBL; NHZQ01000335; PSK42375.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2P7Z2D4; -.
DR STRING; 40998.A0A2P7Z2D4; -.
DR Proteomes; UP000243723; Unassembled WGS sequence.
DR GO; GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
DR GO; GO:0006869; P:lipid transport; IEA:UniProtKB-KW.
DR CDD; cd13289; PH_Osh3p_yeast; 1.
DR Gene3D; 2.40.160.120; -; 1.
DR Gene3D; 3.30.70.3490; -; 1.
DR Gene3D; 2.60.120.680; GOLD domain; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR009038; GOLD_dom.
DR InterPro; IPR036598; GOLD_dom_sf.
DR InterPro; IPR037239; OSBP_sf.
DR InterPro; IPR000648; Oxysterol-bd.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR041680; PH_8.
DR InterPro; IPR001849; PH_domain.
DR PANTHER; PTHR10972:SF216; OXYSTEROL-BINDING PROTEIN HOMOLOG 3; 1.
DR PANTHER; PTHR10972; OXYSTEROL-BINDING PROTEIN-RELATED; 1.
DR Pfam; PF01237; Oxysterol_BP; 1.
DR Pfam; PF15409; PH_8; 1.
DR SMART; SM00233; PH; 1.
DR SUPFAM; SSF144000; Oxysterol-binding protein-like; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF101576; Supernatant protein factor (SPF), C-terminal domain; 1.
DR PROSITE; PS50866; GOLD; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
PE 3: Inferred from homology;
KW Lipid transport {ECO:0000256|ARBA:ARBA00023055};
KW Lipid-binding {ECO:0000256|ARBA:ARBA00023121};
KW Reference proteome {ECO:0000313|Proteomes:UP000243723};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 1..148
FT /note="GOLD"
FT /evidence="ECO:0000259|PROSITE:PS50866"
FT DOMAIN 215..309
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT REGION 165..199
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 366..423
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 436..461
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 496..516
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 539..602
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 165..194
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 368..388
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 551..588
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1002 AA; 109264 MW; 90DF7BDAE21302D6 CRC64;
MEQLQIHSRS YIVRWIRVNA GESISWSLQP HKKSVNFGIF KHPGGKAGNA PNLPTSATLD
APLTPSENEF VKGRRNSTAK EKDGVTAVLD KLQSIGLKCV SWTGKCEADQ VSMGRFDVQE
GEDGMYGLVF DNTFSKTVAK TATFVLMTHP TSAPPKSGAQ LRYTHSQAAG SSTSIGRSPS
LHAVNASSES LPHDAPASVP SLRIPRRASA ASFASGFYTG VMHKKRRKKN QGYARRFFSL
DFTSSTLSYY RNSHASALRG SVPLSLAAIG VDEKRKEFSI DSGAEVWHLR LRNKKDFESW
RRALEKATSS PGSMPSSAII RSARDADGTQ TPVFSDPLVE RDWMRVEELV GRVSGSRDAV
RRLAQDTDPK YNSGNGQHGS SSPGASPVEG NPFFSDLPEK EPQKLPFWKR KASSGGTSSE
SRASLLRRSF SAQGAATTSA SLSGPLSPAG SIPKIRAPST TGVNDEIHDR CMALLRDLDA
TVSEFSSLLA ENRARRRPPV SKTASRMSME SSASADDFFD AEEAPDAVMM SIRHSDEVTD
ERDDFFSDEE SLASSSDGAP ASLQQSTTLT SSSLFPSLSK TPLPSSIPTI QPRLAIPPPR
QPPPSIVSFL RKNAGKDLST VAMPVTANEP LSLLQRLAEP LENVQLLSLA TSNAAKSPLD
RLIYVTAFAI GTLAANRVKE RAVRKPFNPM LGETYELVRP IASGIEKNSG SYRFIAEKVN
HHPVRMAWQA DDLGSKWSLA QTPRPVQKFW GKSVEVNTEG RFRLVVNTTA GSGEKVNGEA
GRKSEERYSW AQPTAYLRNV IAGEKYVEPT GSMTVANETD GSKAVATFKA SGMFSGRSEE
VNVAFFAAGS GQSLDVSVVG TWTKELRRTD TDEVVWRAGN VVKDAAKNWG FSTFAAGLNE
VTGMEEGKVP PTDSRLRPDQ RALEKGELDA AEGVKARLEE RQRGRRKVLE AHGRAHEPAW
FEKVEGLEGE GDEVWRLRSG KDGYWDRRER GDWKGVVDVF ET
//
