ID A0A2P8AWK6_9ACTN Unreviewed; 225 AA.
AC A0A2P8AWK6;
DT 23-MAY-2018, integrated into UniProtKB/TrEMBL.
DT 23-MAY-2018, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=CRP-like cAMP-activated global transcriptional regulator {ECO:0000313|EMBL:PSK64854.1};
GN Name=crp_2 {ECO:0000313|EMBL:PSK64854.1};
GN ORFNames=B0E53_03194 {ECO:0000313|EMBL:PSK64854.1};
OS Micromonospora sp. MH33.
OC Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC Micromonosporaceae; Micromonospora.
OX NCBI_TaxID=1945509 {ECO:0000313|EMBL:PSK64854.1, ECO:0000313|Proteomes:UP000240342};
RN [1] {ECO:0000313|EMBL:PSK64854.1, ECO:0000313|Proteomes:UP000240342}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MH33 {ECO:0000313|EMBL:PSK64854.1,
RC ECO:0000313|Proteomes:UP000240342};
RA Thatcher L.F., Myers C.A., O'Sullivan C.A., Roper M.;
RT "Draft genome sequences of Micromonospora sp. MH33 and MH99.";
RL Submitted (FEB-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PSK64854.1}.
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DR EMBL; MUYZ01000091; PSK64854.1; -; Genomic_DNA.
DR RefSeq; WP_007073398.1; NZ_MUYZ01000091.1.
DR AlphaFoldDB; A0A2P8AWK6; -.
DR OrthoDB; 892842at2; -.
DR Proteomes; UP000240342; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd00038; CAP_ED; 1.
DR Gene3D; 2.60.120.10; Jelly Rolls; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR018488; cNMP-bd_CS.
DR InterPro; IPR000595; cNMP-bd_dom.
DR InterPro; IPR018490; cNMP-bd_dom_sf.
DR InterPro; IPR012318; HTH_CRP.
DR InterPro; IPR014710; RmlC-like_jellyroll.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR24567; CRP FAMILY TRANSCRIPTIONAL REGULATORY PROTEIN; 1.
DR PANTHER; PTHR24567:SF80; CRP-LIKE CAMP-ACTIVATED GLOBAL TRANSCRIPTIONAL REGULATOR; 1.
DR Pfam; PF00027; cNMP_binding; 1.
DR Pfam; PF13545; HTH_Crp_2; 1.
DR SMART; SM00100; cNMP; 1.
DR SMART; SM00419; HTH_CRP; 1.
DR SUPFAM; SSF51206; cAMP-binding domain-like; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS00889; CNMP_BINDING_2; 1.
DR PROSITE; PS50042; CNMP_BINDING_3; 1.
DR PROSITE; PS51063; HTH_CRP_2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000240342}.
FT DOMAIN 10..130
FT /note="Cyclic nucleotide-binding"
FT /evidence="ECO:0000259|PROSITE:PS50042"
FT DOMAIN 144..217
FT /note="HTH crp-type"
FT /evidence="ECO:0000259|PROSITE:PS51063"
SQ SEQUENCE 225 AA; 24819 MW; C893148E0DE63906 CRC64;
MDEVLARSGI FQGVDPEAAE ALAKEMETIE VRKGEVVFNE GEPGDSLYIL LSGKIKVGRR
AADGRQNLIA VMGPSDMVGE LSLFDPGPRT ATATAVTDTR LVRLRKQALR PWLNNRPEIA
EQLLRVLARR LRRTNDSLAD LIFTDVPGRV AKNLLQMAGR FGTRDGGVLR VTHDLTQEEI
AQLVGASRET VNKALADFAS RGWLRLDGKS IIILDPERLA RRARV
//
