ID   A0A2P8AX75_9ACTN        Unreviewed;       191 AA.
AC   A0A2P8AX75;
DT   23-MAY-2018, integrated into UniProtKB/TrEMBL.
DT   23-MAY-2018, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   RecName: Full=HTH tetR-type domain-containing protein {ECO:0000259|PROSITE:PS50977};
GN   ORFNames=B0E53_02971 {ECO:0000313|EMBL:PSK65070.1};
OS   Micromonospora sp. MH33.
OC   Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC   Micromonosporaceae; Micromonospora.
OX   NCBI_TaxID=1945509 {ECO:0000313|EMBL:PSK65070.1, ECO:0000313|Proteomes:UP000240342};
RN   [1] {ECO:0000313|EMBL:PSK65070.1, ECO:0000313|Proteomes:UP000240342}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MH33 {ECO:0000313|EMBL:PSK65070.1,
RC   ECO:0000313|Proteomes:UP000240342};
RA   Thatcher L.F., Myers C.A., O'Sullivan C.A., Roper M.;
RT   "Draft genome sequences of Micromonospora sp. MH33 and MH99.";
RL   Submitted (FEB-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PSK65070.1}.
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DR   EMBL; MUYZ01000080; PSK65070.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2P8AX75; -.
DR   Proteomes; UP000240342; Unassembled WGS sequence.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:UniProt.
DR   Gene3D; 1.10.357.10; Tetracycline Repressor, domain 2; 1.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR001647; HTH_TetR.
DR   SUPFAM; SSF46689; Homeodomain-like; 1.
DR   PROSITE; PS50977; HTH_TETR_2; 1.
PE   4: Predicted;
KW   DNA-binding {ECO:0000256|PROSITE-ProRule:PRU00335};
KW   Reference proteome {ECO:0000313|Proteomes:UP000240342};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT   DOMAIN          9..69
FT                   /note="HTH tetR-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50977"
FT   DNA_BIND        32..51
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00335"
SQ   SEQUENCE   191 AA;  20591 MW;  7ECFE543A2DEB6D7 CRC64;
     MSQHERPGSA RRDELLERAY QYVLAHGLAE LSLRPLAAAI GSSPRVLLFL FGSKDQLIRA
     LLGRARTDEL AALRRAREAG GSDDFVAAVR TTWDWLVDPA HRPMLVLWVQ AYARSLSEPD
     GPWAGFARQT VEDWLGLLAE VGGRADSAGA DPALALALLR GALLDLLATG DAERTTAVVE
     RCLVLVGAAA R
//