ID A0A2P8B0Q0_9ACTN Unreviewed; 573 AA.
AC A0A2P8B0Q0;
DT 23-MAY-2018, integrated into UniProtKB/TrEMBL.
DT 23-MAY-2018, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=Cytochrome bc1 complex cytochrome b subunit {ECO:0000256|ARBA:ARBA00016116};
DE EC=7.1.1.8 {ECO:0000256|ARBA:ARBA00012951};
DE AltName: Full=Cytochrome bc1 reductase complex subunit QcrB {ECO:0000256|ARBA:ARBA00029568};
GN Name=qcrB_2 {ECO:0000313|EMBL:PSK66283.1};
GN ORFNames=B0E53_01738 {ECO:0000313|EMBL:PSK66283.1};
OS Micromonospora sp. MH33.
OC Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC Micromonosporaceae; Micromonospora.
OX NCBI_TaxID=1945509 {ECO:0000313|EMBL:PSK66283.1, ECO:0000313|Proteomes:UP000240342};
RN [1] {ECO:0000313|EMBL:PSK66283.1, ECO:0000313|Proteomes:UP000240342}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MH33 {ECO:0000313|EMBL:PSK66283.1,
RC ECO:0000313|Proteomes:UP000240342};
RA Thatcher L.F., Myers C.A., O'Sullivan C.A., Roper M.;
RT "Draft genome sequences of Micromonospora sp. MH33 and MH99.";
RL Submitted (FEB-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a quinol + 2 Fe(III)-[cytochrome c](out) = a quinone + 2
CC Fe(II)-[cytochrome c](out) + 2 H(+)(out); Xref=Rhea:RHEA:11484,
CC Rhea:RHEA-COMP:10350, Rhea:RHEA-COMP:14399, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:24646, ChEBI:CHEBI:29033, ChEBI:CHEBI:29034,
CC ChEBI:CHEBI:132124; EC=7.1.1.8;
CC Evidence={ECO:0000256|ARBA:ARBA00029351};
CC -!- COFACTOR:
CC Name=heme; Xref=ChEBI:CHEBI:30413;
CC Evidence={ECO:0000256|ARBA:ARBA00001971};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PSK66283.1}.
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DR EMBL; MUYZ01000036; PSK66283.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2P8B0Q0; -.
DR Proteomes; UP000240342; Unassembled WGS sequence.
DR GO; GO:0070469; C:respirasome; IEA:UniProtKB-KW.
DR GO; GO:0008121; F:ubiquinol-cytochrome-c reductase activity; IEA:UniProtKB-EC.
DR GO; GO:0022904; P:respiratory electron transport chain; IEA:InterPro.
DR InterPro; IPR036150; Cyt_b/b6_C_sf.
DR InterPro; IPR005797; Cyt_b/b6_N.
DR InterPro; IPR027387; Cytb/b6-like_sf.
DR InterPro; IPR016174; Di-haem_cyt_TM.
DR PANTHER; PTHR19271; CYTOCHROME B; 1.
DR PANTHER; PTHR19271:SF16; CYTOCHROME B; 1.
DR Pfam; PF13631; Cytochrom_B_N_2; 1.
DR SUPFAM; SSF81648; a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase); 1.
DR SUPFAM; SSF81342; Transmembrane di-heme cytochromes; 1.
DR PROSITE; PS51002; CYTB_NTER; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000240342};
KW Translocase {ECO:0000256|ARBA:ARBA00022967};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 39..58
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 104..123
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 135..155
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 167..189
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 201..224
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 255..274
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 324..344
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 365..384
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 404..424
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 6..232
FT /note="Cytochrome b/b6 N-terminal region profile"
FT /evidence="ECO:0000259|PROSITE:PS51002"
FT REGION 446..472
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 573 AA; 62946 MW; 20F2A6DAD110B5F2 CRC64;
MILDRLARAF DDRLRLSPLT RRALAKVFPD HWSFMLGEIA LYSFVALILT GGYLTLFFDP
SSADRVYHGS YAPLDGATTS AAYASSVRLS WDVRAGLLIR QTHHWAALVF VAAILVHLVR
IFFTGAFRRP RELNWLVGVT MLTLALANGF TGYSMPDDLV SGLGLRIIVS VVESIPLVGS
WLVFLGLGGE FPSDEMIPRL FVTHVLLVPA VLVALVSVHL AMIVRQKHTQ FRGPGRTERN
VVGSLLYPSY TLRSLALFAW VLAVLFALGG LVQINPVWQY GPFAPAQSTA PAQPDWYVAW
GDGALRLFPP WEIHIFGHLV PAPFFPGVVL GGVTFGALYA WPFLERWCTG DRRQHHLLDR
PRDHPVRMGV GVLALTFFGV LVVAAGDDIL ARLLRVPVYD VLNVLRVLVL VLPVLAGMLA
FLLARALRRG DAAGLGELTR ADLRAARRPA GGGDAEAATD EPELPAPDRP GERIELWPDG
DVWRWRYRDE PAGVALLSNR AVLTEQEAAD SARLAYPGVD HVTVPGPPPP SPPGRVRTAL
RRWGNAALGI SLLAAALRQR RAQRRGEDGP ERR
//
