ID   A0A2P8DWP0_9ACTN        Unreviewed;       417 AA.
AC   A0A2P8DWP0;
DT   23-MAY-2018, integrated into UniProtKB/TrEMBL.
DT   23-MAY-2018, sequence version 1.
DT   27-MAR-2024, entry version 16.
DE   SubName: Full=Transmembrane secretion effector {ECO:0000313|EMBL:PSL01633.1};
GN   ORFNames=CLV30_113121 {ECO:0000313|EMBL:PSL01633.1};
OS   Haloactinopolyspora alba.
OC   Bacteria; Actinomycetota; Actinomycetes; Jiangellales; Jiangellaceae;
OC   Haloactinopolyspora.
OX   NCBI_TaxID=648780 {ECO:0000313|EMBL:PSL01633.1, ECO:0000313|Proteomes:UP000243528};
RN   [1] {ECO:0000313|EMBL:PSL01633.1, ECO:0000313|Proteomes:UP000243528}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 45211 {ECO:0000313|EMBL:PSL01633.1,
RC   ECO:0000313|Proteomes:UP000243528};
RA   Goeker M.;
RT   "Genomic Encyclopedia of Archaeal and Bacterial Type Strains, Phase II
RT   (KMG-II): from individual species to whole genera.";
RL   Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane
CC       {ECO:0000256|ARBA:ARBA00004429}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004429}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PSL01633.1}.
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DR   EMBL; PYGE01000013; PSL01633.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2P8DWP0; -.
DR   OrthoDB; 145388at2; -.
DR   Proteomes; UP000243528; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   CDD; cd06173; MFS_MefA_like; 1.
DR   Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 1.
DR   InterPro; IPR020846; MFS_dom.
DR   InterPro; IPR036259; MFS_trans_sf.
DR   InterPro; IPR010290; TM_effector.
DR   PANTHER; PTHR23513; INTEGRAL MEMBRANE EFFLUX PROTEIN-RELATED; 1.
DR   PANTHER; PTHR23513:SF6; MULTIDRUG EFFLUX PUMP TAP; 1.
DR   Pfam; PF05977; MFS_3; 1.
DR   SUPFAM; SSF103473; MFS general substrate transporter; 1.
DR   PROSITE; PS50850; MFS; 1.
PE   4: Predicted;
KW   Antibiotic resistance {ECO:0000256|ARBA:ARBA00023251};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000243528};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        20..41
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        48..71
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        77..98
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        164..189
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        230..252
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        264..284
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        296..314
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        320..340
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        361..381
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        387..406
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          227..417
FT                   /note="Major facilitator superfamily (MFS) profile"
FT                   /evidence="ECO:0000259|PROSITE:PS50850"
SQ   SEQUENCE   417 AA;  42000 MW;  862FDB31704E0156 CRC64;
     MTRSAGPRDL PGAYWRLTGA AGVGAVGEGA FAAAAPLLAA TLTGDPRLVS VVSASVYLPW
     LLLSLVAGAV VDRYDRVGLM WCAQAVQAVI AGVVAILVAS DRLGIPTLAI LVFGLGTCQV
     VAGNAGQAVL PDIVGQRLLH AANGYQQSIV LVGRQFAGPP VGSVLFAAAA ALPFVADAGA
     LAIAAMLLAT LAHSGPRSAA HPPAGHPPAG HPPVRTAIAE GLRWLARHRL LRLLAVLLGV
     NTFCFHLGNA TLVLLATRTL HVDAAGYGLL LATAAVGGLL GGVAGPRIVA GLGTRATLFA
     ALGTNAAVFG GVGVSPDATV LGALLAVNGF ATTLWTIITV SLRQRLVPSR LLGRVNSIYR
     MVGWGLIPLG ALAGGLVAHV FGLRAPFPVA GAIRAAALLA TGLALARAMA VTLDPRE
//