ID   A0A2P8E6T0_9ACTN        Unreviewed;       489 AA.
AC   A0A2P8E6T0;
DT   23-MAY-2018, integrated into UniProtKB/TrEMBL.
DT   23-MAY-2018, sequence version 1.
DT   27-MAR-2024, entry version 14.
DE   SubName: Full=Cell elongation-specific peptidoglycan D,D-transpeptidase {ECO:0000313|EMBL:PSL05166.1};
GN   ORFNames=CLV30_10428 {ECO:0000313|EMBL:PSL05166.1};
OS   Haloactinopolyspora alba.
OC   Bacteria; Actinomycetota; Actinomycetes; Jiangellales; Jiangellaceae;
OC   Haloactinopolyspora.
OX   NCBI_TaxID=648780 {ECO:0000313|EMBL:PSL05166.1, ECO:0000313|Proteomes:UP000243528};
RN   [1] {ECO:0000313|EMBL:PSL05166.1, ECO:0000313|Proteomes:UP000243528}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 45211 {ECO:0000313|EMBL:PSL05166.1,
RC   ECO:0000313|Proteomes:UP000243528};
RA   Goeker M.;
RT   "Genomic Encyclopedia of Archaeal and Bacterial Type Strains, Phase II
RT   (KMG-II): from individual species to whole genera.";
RL   Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the transpeptidase family.
CC       {ECO:0000256|ARBA:ARBA00007171}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PSL05166.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; PYGE01000004; PSL05166.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2P8E6T0; -.
DR   OrthoDB; 9766847at2; -.
DR   Proteomes; UP000243528; Unassembled WGS sequence.
DR   GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR   Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR   Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR   InterPro; IPR012338; Beta-lactam/transpept-like.
DR   InterPro; IPR036138; PBP_dimer_sf.
DR   InterPro; IPR001460; PCN-bd_Tpept.
DR   PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR   PANTHER; PTHR30627:SF24; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE PBPA; 1.
DR   Pfam; PF00905; Transpeptidase; 1.
DR   SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR   SUPFAM; SSF56519; Penicillin binding protein dimerisation domain; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000243528}.
FT   DOMAIN          156..484
FT                   /note="Penicillin-binding protein transpeptidase"
FT                   /evidence="ECO:0000259|Pfam:PF00905"
SQ   SEQUENCE   489 AA;  52460 MW;  D6F1AD36BCD1A8B2 CRC64;
     MNSPIRRISA GCLLLCVALL INITYVQAFW ADELNARPEN RRVLLDEYSR ERGPILLADD
     TPIARSVPDD SEFEFQRQYP QGPMYAPLTG YYSRFYGRTG LERAQNDILS GEDDRLFVRR
     LIDMATGEEP KGGAVKLTVQ PAAQEAAYEG LEGYKGAVVA IDIETGAILA AANRPSYDPN
     AIATHDFDEQ TAAKNDLDSD EDQPALNRAF AQRLPPGSVF KLVTAAAALE SGEYEPDSEV
     PGPAQYDLPL SDKPLGNYFE GACGPGGTTT LIEALRISCN TAFAHIGNEL GHDALLDQAE
     RFGFNTQPLT DSDMNAATSV FPDDASEPET AYSAIGQFEV AATPLQIAMV SAAIANDGVL
     MDPYLIREVR GPDLVSPIEQ TEPEELTEAV SSETAEQLTD MMVEVVDDGT GENAQIEGID
     VAGKTGTAET GREDEPPYAW FTSFAPADEP RVAVAVVIEE APDTAREDIG GGALAAPIAR
     DVMEAVLGS
//