ID A0A2P8H1J7_9BACL Unreviewed; 516 AA.
AC A0A2P8H1J7;
DT 23-MAY-2018, integrated into UniProtKB/TrEMBL.
DT 23-MAY-2018, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE RecName: Full=Galactose-1-phosphate uridylyltransferase {ECO:0000256|HAMAP-Rule:MF_00571};
DE Short=Gal-1-P uridylyltransferase {ECO:0000256|HAMAP-Rule:MF_00571};
DE EC=2.7.7.12 {ECO:0000256|HAMAP-Rule:MF_00571};
DE AltName: Full=UDP-glucose--hexose-1-phosphate uridylyltransferase {ECO:0000256|HAMAP-Rule:MF_00571};
GN Name=galT {ECO:0000256|HAMAP-Rule:MF_00571};
GN ORFNames=B0H99_106106 {ECO:0000313|EMBL:PSL40093.1};
OS Planomicrobium soli.
OC Bacteria; Bacillota; Bacilli; Bacillales; Planococcaceae; Planomicrobium.
OX NCBI_TaxID=1176648 {ECO:0000313|EMBL:PSL40093.1, ECO:0000313|Proteomes:UP000242682};
RN [1] {ECO:0000313|EMBL:PSL40093.1, ECO:0000313|Proteomes:UP000242682}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CGMCC 1.12259 {ECO:0000313|EMBL:PSL40093.1,
RC ECO:0000313|Proteomes:UP000242682};
RA Whitman W.;
RT "Genomic Encyclopedia of Type Strains, Phase III (KMG-III): the genomes of
RT soil and plant-associated and newly described type strains.";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=alpha-D-galactose 1-phosphate + UDP-alpha-D-glucose = alpha-D-
CC glucose 1-phosphate + UDP-alpha-D-galactose; Xref=Rhea:RHEA:13989,
CC ChEBI:CHEBI:58336, ChEBI:CHEBI:58601, ChEBI:CHEBI:58885,
CC ChEBI:CHEBI:66914; EC=2.7.7.12;
CC Evidence={ECO:0000256|ARBA:ARBA00001107, ECO:0000256|HAMAP-
CC Rule:MF_00571};
CC -!- PATHWAY: Carbohydrate metabolism; galactose metabolism.
CC {ECO:0000256|ARBA:ARBA00004947, ECO:0000256|HAMAP-Rule:MF_00571}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496,
CC ECO:0000256|HAMAP-Rule:MF_00571}.
CC -!- SIMILARITY: Belongs to the galactose-1-phosphate uridylyltransferase
CC type 2 family. {ECO:0000256|ARBA:ARBA00008706, ECO:0000256|HAMAP-
CC Rule:MF_00571}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PSL40093.1}.
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DR EMBL; PYAT01000006; PSL40093.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2P8H1J7; -.
DR OrthoDB; 2293at2; -.
DR UniPathway; UPA00214; -.
DR Proteomes; UP000242682; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0008108; F:UDP-glucose:hexose-1-phosphate uridylyltransferase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006012; P:galactose metabolic process; IEA:UniProtKB-UniRule.
DR HAMAP; MF_00571; GalP_UDP_trans; 1.
DR InterPro; IPR000766; GalP_uridyl_Trfase_II.
DR InterPro; IPR023425; GalP_uridyl_Trfase_II_CS.
DR InterPro; IPR005850; GalP_Utransf_C.
DR InterPro; IPR005849; GalP_Utransf_N.
DR NCBIfam; TIGR01239; galT_2; 1.
DR PANTHER; PTHR39191:SF1; DUF4922 DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR39191; GALACTOSE-1-PHOSPHATE URIDYLYLTRANSFERASE; 1.
DR Pfam; PF02744; GalP_UDP_tr_C; 1.
DR Pfam; PF01087; GalP_UDP_transf; 1.
DR PIRSF; PIRSF006005; GalT_BS; 1.
DR PROSITE; PS01163; GAL_P_UDP_TRANSF_II; 1.
PE 3: Inferred from homology;
KW Carbohydrate metabolism {ECO:0000256|ARBA:ARBA00023277, ECO:0000256|HAMAP-
KW Rule:MF_00571};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490, ECO:0000256|HAMAP-Rule:MF_00571};
KW Galactose metabolism {ECO:0000256|ARBA:ARBA00023144, ECO:0000256|HAMAP-
KW Rule:MF_00571};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695, ECO:0000256|HAMAP-
KW Rule:MF_00571};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|HAMAP-
KW Rule:MF_00571}.
FT DOMAIN 19..229
FT /note="Galactose-1-phosphate uridyl transferase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF01087"
FT DOMAIN 246..439
FT /note="Galactose-1-phosphate uridyl transferase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02744"
SQ SEQUENCE 516 AA; 58726 MW; BAFDE1CD40DDA4B8 CRC64;
MIYQNLQGLI HQTLEAQLIE AADVSYARNQ VMNLLGLESF PEEAIEAAHD SIPNLLENII
AYAIENGIIE DVLDDKEILS ANIMNCFVAR PSAINSAFWQ KYKESPIVAT DYFYNLSKNS
NYIQMNRIAK NISYKADSAY GALDITINLS KPEKDPEQIK RERTLKPTSN YPKCLLCREN
EGYTGRTGYP ARANHRIVNV PLQKENWYLQ YSPYVYYNEH SILLSEEHRD MKIDKNVFER
LLLFTDKFPH YFIGSNADLP IVGGSILSHD HYQAGRYEFA MTQAEDAFSF ELASFPEIKA
AVVKWPLSVI RLRGTNIDHL VAASDYVFQT WKSYSDEQAD VAAFTDGTRH NTITPIARNK
NGQFEIDLVL RNNRTSDEHP LGIFHPHADV HHIKKENIGL IEVMGLAVLP PRLKGELEEI
QRFLTGDSSQ PAEYHMEWAE EIKAEYGSFA NSEEAEAVLQ KELGKKFVRV LEDAGVLKDR
KAFERFIHTL NGVGGHIHEH SNTTTHGKLD GIHLNK
//
