ID A0A2P8K9Z2_9BURK Unreviewed; 369 AA.
AC A0A2P8K9Z2;
DT 23-MAY-2018, integrated into UniProtKB/TrEMBL.
DT 23-MAY-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=GTP-binding protein {ECO:0000313|EMBL:PSL79768.1};
GN ORFNames=C7T35_35925 {ECO:0000313|EMBL:PSL79768.1}, GXN78_35955
GN {ECO:0000313|EMBL:NDZ18139.1};
OS Variovorax sp. WS11.
OG Plasmid pVarWS11_2 {ECO:0000313|EMBL:NDZ18139.1}.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Comamonadaceae; Variovorax.
OX NCBI_TaxID=1105204 {ECO:0000313|EMBL:PSL79768.1, ECO:0000313|Proteomes:UP000241151};
RN [1] {ECO:0000313|EMBL:PSL79768.1, ECO:0000313|Proteomes:UP000241151}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WS11 {ECO:0000313|EMBL:PSL79768.1,
RC ECO:0000313|Proteomes:UP000241151};
RA Crombie A.T., Mejia-Florez N.L., Murrell C.;
RT "Isoprene degraders from the Poplar phyllosphere.";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:NDZ18139.1, ECO:0000313|Proteomes:UP000479786}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WS11 {ECO:0000313|EMBL:NDZ18139.1,
RC ECO:0000313|Proteomes:UP000479786};
RC PLASMID=pVarWS11_2 {ECO:0000313|EMBL:NDZ18139.1};
RA Dawson R.A., Larke-Mejia N.L., Crombie A.T., Ul-Haque M.F., Murrell J.C.;
RT "Isoprene oxidation by the Gram negative model bacterium Variovorax sp.
RT WS11.";
RL Submitted (FEB-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=GTP + H2O = GDP + H(+) + phosphate; Xref=Rhea:RHEA:19669,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:37565,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:58189;
CC Evidence={ECO:0000256|ARBA:ARBA00001702};
CC PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:19670;
CC Evidence={ECO:0000256|ARBA:ARBA00001702};
CC -!- SIMILARITY: Belongs to the SIMIBI class G3E GTPase family. ZNG1
CC subfamily. {ECO:0000256|ARBA:ARBA00034320}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PSL79768.1}.
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DR EMBL; JAAGOW010000005; NDZ18139.1; -; Genomic_DNA.
DR EMBL; PXZZ01000084; PSL79768.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2P8K9Z2; -.
DR OrthoDB; 9808822at2; -.
DR Proteomes; UP000241151; Unassembled WGS sequence.
DR Proteomes; UP000479786; Unassembled WGS sequence.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR CDD; cd03112; CobW-like; 1.
DR Gene3D; 3.30.1220.10; CobW-like, C-terminal domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR036627; CobW-likC_sf.
DR InterPro; IPR011629; CobW-like_C.
DR InterPro; IPR003495; CobW/HypB/UreG_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR13748:SF59; COBW C-TERMINAL DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR13748; COBW-RELATED; 1.
DR Pfam; PF02492; cobW; 1.
DR Pfam; PF07683; CobW_C; 1.
DR SMART; SM00833; CobW_C; 1.
DR SUPFAM; SSF90002; Hypothetical protein YjiA, C-terminal domain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Plasmid {ECO:0000313|EMBL:NDZ18139.1}.
FT DOMAIN 251..346
FT /note="CobW C-terminal"
FT /evidence="ECO:0000259|SMART:SM00833"
FT REGION 340..369
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 340..354
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 369 AA; 40141 MW; A0EF277B700491E6 CRC64;
MSGHFSSLLA SDRPGRDRVP VTVLTGFLGS GKTTLLNELL REPDLQGTAV IVNEFGEIGI
DHDLIAQTTE DTILLANGCM CCAVRGDLIG ALVSLGERDA TGGPALRQVV IETSGLADPA
PILRTLMGEP AVKDRFVLSG VCCTVDAVLA LGTLERHPEA ARQVAMADQL FLTKMDLLKE
PISPALLDRL RALNPTGVVN QQRDEHTRVL RQTMETRTND SRSVPVESGL SYRPIPAAGG
AGEPSPHSGG INSFVIVRDD PLPRDGFYAW LDMVIAMRGE DLLRVKGIVN LQEQPEQPLV
FHGVQHLYQP PESLPAWPSA DRRTRIVFIT RGVDAESMDE SLRVFERRRR QRPPAASSPD
PSSKSKETP
//
