ID A0A2P8PW66_9ACTN Unreviewed; 859 AA.
AC A0A2P8PW66;
DT 23-MAY-2018, integrated into UniProtKB/TrEMBL.
DT 23-MAY-2018, sequence version 1.
DT 24-JAN-2024, entry version 17.
DE SubName: Full=Polynucleotide kinase-phosphatase {ECO:0000313|EMBL:PSM38245.1};
GN ORFNames=C6Y14_38650 {ECO:0000313|EMBL:PSM38245.1};
OS Streptomyces dioscori.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces; Streptomyces aurantiacus group.
OX NCBI_TaxID=2109333 {ECO:0000313|EMBL:PSM38245.1, ECO:0000313|Proteomes:UP000240429};
RN [1] {ECO:0000313|EMBL:PSM38245.1, ECO:0000313|Proteomes:UP000240429}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=A217 {ECO:0000313|EMBL:PSM38245.1,
RC ECO:0000313|Proteomes:UP000240429};
RA Zhikuan W.;
RT "Streptomyces dioscori sp. nov., a novel endophytic actinobacterium
RT isolated from bulbil of Dioscorea bulbifera L.";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PSM38245.1}.
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DR EMBL; PYBJ01000031; PSM38245.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2P8PW66; -.
DR OrthoDB; 9807890at2; -.
DR Proteomes; UP000240429; Unassembled WGS sequence.
DR GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd07423; MPP_Prp_like; 1.
DR Gene3D; 3.60.21.10; -; 1.
DR Gene3D; 3.30.470.30; DNA ligase/mRNA capping enzyme; 2.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR004843; Calcineurin-like_PHP_ApaH.
DR InterPro; IPR029052; Metallo-depent_PP-like.
DR InterPro; IPR041780; MPP_PrpE-like.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR024028; PNKP_bac.
DR InterPro; IPR032380; PNKP_ligase_dom.
DR NCBIfam; TIGR04075; bacter_Pnkp; 1.
DR PANTHER; PTHR12435:SF2; PROTEIN KTI12 HOMOLOG; 1.
DR PANTHER; PTHR12435; UNCHARACTERIZED; 1.
DR Pfam; PF13671; AAA_33; 1.
DR Pfam; PF00149; Metallophos; 1.
DR Pfam; PF16542; PNKP_ligase; 1.
DR SUPFAM; SSF56091; DNA ligase/mRNA capping enzyme, catalytic domain; 1.
DR SUPFAM; SSF56300; Metallo-dependent phosphatases; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:PSM38245.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000240429};
KW Transferase {ECO:0000313|EMBL:PSM38245.1}.
FT DOMAIN 190..376
FT /note="Calcineurin-like phosphoesterase"
FT /evidence="ECO:0000259|Pfam:PF00149"
FT DOMAIN 464..854
FT /note="Polynucleotide kinase-phosphatase ligase"
FT /evidence="ECO:0000259|Pfam:PF16542"
SQ SEQUENCE 859 AA; 94087 MW; E1AE57FE57D95D51 CRC64;
MSDNGTRVRT LPVTDLSLVV LIGASGSGKS TFARRHFKPT EVISSDFCRG LVADDENDQS
ASKDAFDVLD YIAGKRLAAG RRTVVDATSV QSDSRRQLIE LARKHDVLPI AIVLDVPEEV
CAERNAARTD RAGMPRRVIQ RHIRELRRSL RQLEREGFRK VHVLRGVEEV ETAEVRTEKR
YNDLTHLTGP FDIIGDIHGC ASELDALLAK LGYVDGVHPE GRTAVFVGDL VDRGPDSPGV
LRRVMSMVGS GDALCVPGNH ENKYGRHLKG RKVQPTHGLA ETIAQMENES DEFKRQVREF
VDGLVSHYVL DGGGLVVCHA GLPEKYHGRT SGRVRSHALY GETTGETDEF GLPVRYPWAE
DYRGRAAVVY GHTPVPEATW LNNTICLDTG AVFGGKLTAL RWPARELVDV PAEKVWYEPV
RPLASEAPGG HEGRPLDLAD VHGRRVVETR HAGRVAVREE NAAAALEVMS RFAVDPRLMP
YLPPTMAPTA TSRVEGYLEH PAEAFEQYRA DGVARVVCEE KHMGSRAVAL VCRTAETARE
RFGTTTGATG ALYTRTGRPF FPEPTGGSVD SGAGGSLTEE ILGRVRDAVT EAGLWEELDT
DWLLLDAELL PWSLKASGLL RSQYAAVGAA AGAVFPGAVA ALERAAARGV EVGDLLTKQR
ERAVDAAAFT DAYRRYCWPT SGLEGVRLAP FQILATRGRS LAAVPHDEQL TLIDRLVTAD
PSGLLSTTRR LFVDTDDPAS VRAGVDWWLE MTGRGGEGMV VKPVGAVART PKGRLVQPGI
KCRGREYLRI IYGPEYTRPE NLDRLRGRSL DHKRSLALRE YALGLESLDR LADGEPLWRV
HEAVFGVLAL ESEPVDPRL
//
