ID A0A2P8PZ73_9ACTN Unreviewed; 1332 AA.
AC A0A2P8PZ73;
DT 23-MAY-2018, integrated into UniProtKB/TrEMBL.
DT 23-MAY-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=ATP-dependent RNA helicase HrpA {ECO:0000313|EMBL:PSM39291.1};
GN ORFNames=C6Y14_33145 {ECO:0000313|EMBL:PSM39291.1};
OS Streptomyces dioscori.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces; Streptomyces aurantiacus group.
OX NCBI_TaxID=2109333 {ECO:0000313|EMBL:PSM39291.1, ECO:0000313|Proteomes:UP000240429};
RN [1] {ECO:0000313|EMBL:PSM39291.1, ECO:0000313|Proteomes:UP000240429}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=A217 {ECO:0000313|EMBL:PSM39291.1,
RC ECO:0000313|Proteomes:UP000240429};
RA Zhikuan W.;
RT "Streptomyces dioscori sp. nov., a novel endophytic actinobacterium
RT isolated from bulbil of Dioscorea bulbifera L.";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PSM39291.1}.
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DR EMBL; PYBJ01000026; PSM39291.1; -; Genomic_DNA.
DR OrthoDB; 9805617at2; -.
DR Proteomes; UP000240429; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0003724; F:RNA helicase activity; IEA:InterPro.
DR CDD; cd17989; DEXHc_HrpA; 1.
DR CDD; cd18791; SF2_C_RHA; 1.
DR Gene3D; 1.20.120.1080; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR011709; DEAD-box_helicase_OB_fold.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR048333; HA2_WH.
DR InterPro; IPR007502; Helicase-assoc_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR024590; HrpA_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR010222; RNA_helicase_HrpA.
DR NCBIfam; TIGR01967; DEAH_box_HrpA; 1.
DR PANTHER; PTHR18934; ATP-DEPENDENT RNA HELICASE; 1.
DR PANTHER; PTHR18934:SF83; PRE-MRNA-SPLICING FACTOR ATP-DEPENDENT RNA HELICASE DHX16; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF11898; DUF3418; 1.
DR Pfam; PF21010; HA2_C; 1.
DR Pfam; PF04408; HA2_N; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF07717; OB_NTP_bind; 1.
DR SMART; SM00382; AAA; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00847; HA2; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000313|EMBL:PSM39291.1};
KW Hydrolase {ECO:0000313|EMBL:PSM39291.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000240429}.
FT DOMAIN 87..251
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 279..446
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 642..661
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 642..658
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1332 AA; 151199 MW; 34641C7B1CE61043 CRC64;
MSTHPAPALG DLASRLAELS LRDAHRLGRR LEGARRIRKP EARAAVTAEI ETEVARAETR
MAERRGRVPT VSYPEQLPVS QKKDVIADAI RDHQVVIVAG ETGSGKTTQI PKICLELGRG
VRGMIGHTQP RRIAARTVAE RVADELDTPL GEAVGWKVRF TDQVSPEATF VKLMTDGILL
AEVQTDRELR AYDTIIIDEA HERSLNIDFL LGYLAQLLPK RPDLKVVITS ATIDPERFSR
HFGDAPIVEV SGRTYPVEVR YRPLLEEDGD DADRDQITAI CDAVEELQGE GKGDILVFLS
GEREIRDTAD ALEKRKYRFT EVLPLYARLS HAEQHRVFQQ HTGRRIVLAT NVAETSLTVP
GIKYVIDPGN ARISRYSHRT KVQRLPIEAI SQASANQRKG RCGRTSDGIC IRLYSEDDFL
ARPEFTDAEI LRTNLASVIL QMTAAGLGEI EKFPFIDPPD HRNIRDGVQL LQELNALDPT
EKDPRKRLTD TGRKLAQLPV DPRLARMVLE ADKNGCVREV MVIAAALSIQ DPRERPSEKQ
TQADQQHARF KDETSDFLAY LNLWRYVREQ QKERGSSSFR RMCKQEYLNF LRIREWQDIY
TQLRTVAKQM GIQLNEDDAP EQHVHLSLLA GLLSHIGMKD VKETGKEGGK DGGKDGRSSA
KNDYVGARNA KFAIFPGSAL FKKPPRFVMS AELVETSRLW ARVNAKIEPE WIEPLAEHLL
KRTYSEPHWE KDQAAVMAYE KVTLYGVPIV AQRKVNYGRI DPEISRELFI RNALVEGDWR
THHKFFSDNR RLLTEVEELE HRARRRDILV DDDTLFDFYE ERVPAHVVSG AHFDSWWKHK
RQEEPELLDF ERSMLIRETA GAVTKDDYPD SWRQGRLKFP VTYQFEPGAD ADGVTVHIPL
QVLNQVTDEG FEWQIPGLRE QVVTELIRSL PKPIRRNYVP APNFAQRFLE RAVPLQEPLT
VTMARELKRM VGVPLTADDF DWSRLDDHLK ITFRIVDERR RKLAEDKDLE ALKVRLKPKA
RQAISQAAAA TAQREGGESL ERTGLTDWTI GSLTRLFETR RAGQPVKAYP ALVDEGPKAN
TVSVRLFDTE AEQQQAMWKG TRRLILRNIP VNPAKFASDK LTNAQKLALS ANPHGSIQAL
FDDCATAAAD KLIGDFGGPA WDEESYRKLY DKVRAEIVDT TVRTVGQVEQ VLAAWQACER
RLKGVRSPVL LANLTDVRTQ LDALVRPGFV TATGLRRLPD LMRYLVAADR RLQQMPTNAQ
RDTSRMEKVH EMQDEYAWLL EQLPQGRPVP SSVRDIRWMI EELRVSYFAH ALGTAYPVSD
KRIVKAIDAA AP
//
