ID A0A2P8VPN8_9ENTR Unreviewed; 430 AA.
AC A0A2P8VPN8;
DT 23-MAY-2018, integrated into UniProtKB/TrEMBL.
DT 23-MAY-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=Tol-Pal system protein TolB {ECO:0000256|HAMAP-Rule:MF_00671};
DE Flags: Precursor;
GN Name=tolB {ECO:0000256|HAMAP-Rule:MF_00671,
GN ECO:0000313|EMBL:PSN09523.1};
GN ORFNames=C7G83_01885 {ECO:0000313|EMBL:PSN09523.1};
OS Siccibacter turicensis.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Siccibacter.
OX NCBI_TaxID=357233 {ECO:0000313|EMBL:PSN09523.1, ECO:0000313|Proteomes:UP000240212};
RN [1] {ECO:0000313|EMBL:PSN09523.1, ECO:0000313|Proteomes:UP000240212}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=6100069499-17 {ECO:0000313|EMBL:PSN09523.1,
RC ECO:0000313|Proteomes:UP000240212};
RA Lepuschitz S., Pekard-Amenitsch S., Haunold R., Schill S., Mach R.,
RA Allerberger F., Ruppitsch W., Forsythe S.J.;
RT "Draft genome sequence of the first documented clinical Siccibacter
RT turicensis isolate in Austria.";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Part of the Tol-Pal system, which plays a role in outer
CC membrane invagination during cell division and is important for
CC maintaining outer membrane integrity. TolB occupies a key intermediary
CC position in the Tol-Pal system because it communicates directly with
CC both membrane-embedded components, Pal in the outer membrane and TolA
CC in the inner membrane. {ECO:0000256|HAMAP-Rule:MF_00671}.
CC -!- SUBUNIT: The Tol-Pal system is composed of five core proteins: the
CC inner membrane proteins TolA, TolQ and TolR, the periplasmic protein
CC TolB and the outer membrane protein Pal. They form a network linking
CC the inner and outer membranes and the peptidoglycan layer.
CC {ECO:0000256|HAMAP-Rule:MF_00671}.
CC -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000256|ARBA:ARBA00004418,
CC ECO:0000256|HAMAP-Rule:MF_00671}.
CC -!- SIMILARITY: Belongs to the TolB family. {ECO:0000256|ARBA:ARBA00009820,
CC ECO:0000256|HAMAP-Rule:MF_00671}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PSN09523.1}.
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DR EMBL; PYEP01000001; PSN09523.1; -; Genomic_DNA.
DR RefSeq; WP_024548042.1; NZ_RYYT01000002.1.
DR AlphaFoldDB; A0A2P8VPN8; -.
DR STRING; 1388748.GCA_000463155_01559; -.
DR OrthoDB; 9802240at2; -.
DR Proteomes; UP000240212; Unassembled WGS sequence.
DR GO; GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-UniRule.
DR GO; GO:0017038; P:protein import; IEA:InterPro.
DR Gene3D; 2.120.10.30; TolB, C-terminal domain; 1.
DR Gene3D; 3.40.50.10070; TolB, N-terminal domain; 1.
DR HAMAP; MF_00671; TolB; 1.
DR InterPro; IPR011042; 6-blade_b-propeller_TolB-like.
DR InterPro; IPR011659; PD40.
DR InterPro; IPR014167; Tol-Pal_TolB.
DR InterPro; IPR007195; TolB_N.
DR NCBIfam; TIGR02800; propeller_TolB; 1.
DR PANTHER; PTHR42972; TOL-PAL SYSTEM PROTEIN TOLB; 1.
DR PANTHER; PTHR42972:SF8; TOL-PAL SYSTEM PROTEIN TOLB; 1.
DR Pfam; PF07676; PD40; 4.
DR Pfam; PF04052; TolB_N; 1.
DR SUPFAM; SSF52964; TolB, N-terminal domain; 1.
DR SUPFAM; SSF69304; Tricorn protease N-terminal domain; 1.
PE 3: Inferred from homology;
KW Cell cycle {ECO:0000256|HAMAP-Rule:MF_00671};
KW Cell division {ECO:0000256|HAMAP-Rule:MF_00671};
KW Periplasm {ECO:0000256|ARBA:ARBA00022764, ECO:0000256|HAMAP-Rule:MF_00671};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|HAMAP-Rule:MF_00671}.
FT SIGNAL 1..21
FT /evidence="ECO:0000256|HAMAP-Rule:MF_00671"
FT CHAIN 22..430
FT /note="Tol-Pal system protein TolB"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_00671"
FT /id="PRO_5015206536"
FT DOMAIN 23..122
FT /note="TolB N-terminal"
FT /evidence="ECO:0000259|Pfam:PF04052"
SQ SEQUENCE 430 AA; 46008 MW; 02FCFBFDA2EF6A23 CRC64;
MKQALRVAFG FLMLWAAVLH AEVRIEITQG VDSARPIGVV PFQWAGPGAA PEDIGGIVSA
DLRNSGKFNP LDRARLPQQP GTAQEVQPAA WSALGIDAVV VGQVTPNADG SYNVAYQLVD
TGAAPGTVLA QNNFKVNKQW LRYAGHTASD EVFEKLTGIK GAFRTRIAYV VQTNGGQFPY
ELRVSDYDGY NQFVVHRSPQ PLMSPAWSPD GSKVAYVTFE SGRSALVIQT LSNGAVRQVA
SFPRHNGAPS FSPDGTKLAF ALSKTGSLNL YVMDIGSGQI RQVTDGRSNN TEPTWFPDSQ
TLAYTSDQAG RPQVYKVNIN GGTPQRLTWE GSQNQDADVS SDGKFMVMVS SNGGAQHIAK
QDLVSGGVQT LSSTFLDETP SLAPNGTMVI YSSSQGMGSV LNLVSTDGRF KARLPATDGQ
VKSPAWSPYL
//
