ID A0A2R2MRQ1_LINUN Unreviewed; 540 AA.
AC A0A2R2MRQ1;
DT 23-MAY-2018, integrated into UniProtKB/TrEMBL.
DT 23-MAY-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Organic cation transporter protein-like {ECO:0000313|RefSeq:XP_023932818.1};
GN Name=LOC106181308 {ECO:0000313|RefSeq:XP_023932818.1};
OS Lingula unguis.
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Brachiopoda; Linguliformea;
OC Lingulata; Lingulida; Linguloidea; Lingulidae; Lingula.
OX NCBI_TaxID=7574 {ECO:0000313|Proteomes:UP000085678, ECO:0000313|RefSeq:XP_023932818.1};
RN [1] {ECO:0000313|RefSeq:XP_023932818.1}
RP IDENTIFICATION.
RC TISSUE=Gonads {ECO:0000313|RefSeq:XP_023932818.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_023932818.1; XM_024077050.1.
DR AlphaFoldDB; A0A2R2MRQ1; -.
DR EnsemblMetazoa; XM_024077050.1; XP_023932818.1; LOC106181308.
DR KEGG; lak:106181308; -.
DR InParanoid; A0A2R2MRQ1; -.
DR OrthoDB; 2968007at2759; -.
DR Proteomes; UP000085678; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 1.
DR InterPro; IPR020846; MFS_dom.
DR InterPro; IPR005828; MFS_sugar_transport-like.
DR InterPro; IPR036259; MFS_trans_sf.
DR PANTHER; PTHR24064:SF530; ORGANIC CATION_CARNITINE TRANSPORTER 4; 1.
DR PANTHER; PTHR24064; SOLUTE CARRIER FAMILY 22 MEMBER; 1.
DR Pfam; PF00083; Sugar_tr; 1.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
DR PROSITE; PS50850; MFS; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000085678};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 7..29
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 143..161
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 167..188
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 200..221
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 227..245
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 314..332
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 344..363
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 375..393
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 399..425
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 464..484
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 59..489
FT /note="Major facilitator superfamily (MFS) profile"
FT /evidence="ECO:0000259|PROSITE:PS50850"
SQ SEQUENCE 540 AA; 60124 MW; A9C498D65D2D0085 CRC64;
MPQFEDILLK VGMDFIGGFS MLALVFVGAD PGWKCTNQYG NQTLNDSLTV YNVTETASVA
VPLLYNSSNQ GEDVVEIGKC TKSGLPCSGH TFNPDFTSIV TEWDLICNRD FISDTISSLQ
MAGVLIGSLV FGQLGDAFGR KKVYFFALLF TSIIGAAQAI TNGWIQFAAL RFINGTGIGG
CIVAGYIWSV EFLGPKYRPV VGGLGLWPLG SLVQVLLGYF IREWRTFLLS TTLPGLSFVI
AWWFLPESPR WLLSQGRYDE VVTIAERIAK GNKKPLPDMD AFVQQCEEEM HLAQRGRRYG
FWDLFRTPTL TRTTTIIMFI WFTNSLLGYG LLFNLKNLPG NKYVHLAINA SLSYFAAILI
LILTRWFGRS RIVNVSMLAA AFLLIPLIVL VAIGRYTELW MVVSVISNIA ATSITISWQA
VFILTSESYP TPIRNQGLGF ASMSARIGGI IAPQMAYVTK FWQGTPYVIS VCFALVAALV
TCFLPETRQK ALEDGVPPRS WCFCMAKRKK RSYNRAKNTD VPLHELMLQK DEGARFTDNI
//
