ID   A0A2R2W7W2_9MICO        Unreviewed;       376 AA.
AC   A0A2R2W7W2;
DT   20-JUN-2018, integrated into UniProtKB/TrEMBL.
DT   20-JUN-2018, sequence version 1.
DT   24-JAN-2024, entry version 20.
DE   SubName: Full=Prephenate dehydrogenase {ECO:0000313|EMBL:ARC56609.1};
GN   Name=tyrA_1 {ECO:0000313|EMBL:ARC56609.1};
GN   ORFNames=AS850_05920 {ECO:0000313|EMBL:ARC56609.1};
OS   Frondihabitans sp. 762G35.
OC   Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Microbacteriaceae;
OC   Frondihabitans.
OX   NCBI_TaxID=1446794 {ECO:0000313|EMBL:ARC56609.1, ECO:0000313|Proteomes:UP000264876};
RN   [1] {ECO:0000313|EMBL:ARC56609.1, ECO:0000313|Proteomes:UP000264876}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=762G35 {ECO:0000313|EMBL:ARC56609.1,
RC   ECO:0000313|Proteomes:UP000264876};
RA   Liu Y., Raaijmakers J.M., de Jager V.C.L.;
RT   "Frondihabitans sp. 762G35 genome sequence.";
RL   Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; CP014619; ARC56609.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2R2W7W2; -.
DR   Proteomes; UP000264876; Chromosome.
DR   GO; GO:0070403; F:NAD+ binding; IEA:InterPro.
DR   GO; GO:0008977; F:prephenate dehydrogenase (NAD+) activity; IEA:InterPro.
DR   GO; GO:0004665; F:prephenate dehydrogenase (NADP+) activity; IEA:InterPro.
DR   GO; GO:0006571; P:tyrosine biosynthetic process; IEA:InterPro.
DR   Gene3D; 1.10.3660.10; 6-phosphogluconate dehydrogenase C-terminal like domain; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR   InterPro; IPR045865; ACT-like_dom_sf.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR046825; PDH_C.
DR   InterPro; IPR046826; PDH_N.
DR   InterPro; IPR003099; Prephen_DH.
DR   PANTHER; PTHR21363; PREPHENATE DEHYDROGENASE; 1.
DR   PANTHER; PTHR21363:SF0; PREPHENATE DEHYDROGENASE [NADP(+)]; 1.
DR   Pfam; PF20463; PDH_C; 1.
DR   Pfam; PF02153; PDH_N; 1.
DR   SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR   SUPFAM; SSF55021; ACT-like; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR   PROSITE; PS51176; PDH_ADH; 1.
PE   4: Predicted;
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000264876}.
FT   DOMAIN          23..300
FT                   /note="Prephenate/arogenate dehydrogenase"
FT                   /evidence="ECO:0000259|PROSITE:PS51176"
SQ   SEQUENCE   376 AA;  38683 MW;  AB39100D35F84AB4 CRC64;
     MTPGDVGGEV AGAGHPAPRR LDGTVRIVGA GLLGASIGLG LRRQGVDVVL DDVSPASLRL
     AIDYGAGRAP LEGDTPTLVV VCVPPDVTAA IVARELETFP DALVTDVASV KVAPLRALQE
     AGADVSRYIG SHPMAGRERG GPISARADLF IGRPWVVAGH DGISYRAAAA LEDLILDLGA
     TPIEMTPEEH DAGVAVVSHA PQVVASLMAA RLRDAPDASL GLAGQGVRDV TRIASSDPAL
     WVQILGANAS RVEEVLRALR DDLDDVLGAL AAPEHPGALR ALAESIGAGN AGVARLPGKH
     GQSTTFTQVV VMVDDTPGQL ALLLTEIGDI GVNLEDLRLE HSPGAQFGLA EVSVVPEHAE
     RLVAELVRRG WTIAGS
//