ID A0A2R2W9T9_9MICO Unreviewed; 510 AA.
AC A0A2R2W9T9;
DT 20-JUN-2018, integrated into UniProtKB/TrEMBL.
DT 20-JUN-2018, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=D-xylose-proton symporter {ECO:0000313|EMBL:ARC57292.1};
GN Name=xylE {ECO:0000313|EMBL:ARC57292.1};
GN ORFNames=AS850_09410 {ECO:0000313|EMBL:ARC57292.1};
OS Frondihabitans sp. 762G35.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Microbacteriaceae;
OC Frondihabitans.
OX NCBI_TaxID=1446794 {ECO:0000313|EMBL:ARC57292.1, ECO:0000313|Proteomes:UP000264876};
RN [1] {ECO:0000313|EMBL:ARC57292.1, ECO:0000313|Proteomes:UP000264876}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=762G35 {ECO:0000313|EMBL:ARC57292.1,
RC ECO:0000313|Proteomes:UP000264876};
RA Liu Y., Raaijmakers J.M., de Jager V.C.L.;
RT "Frondihabitans sp. 762G35 genome sequence.";
RL Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the major facilitator superfamily. Sugar
CC transporter (TC 2.A.1.1) family. {ECO:0000256|ARBA:ARBA00010992,
CC ECO:0000256|RuleBase:RU003346}.
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DR EMBL; CP014619; ARC57292.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2R2W9T9; -.
DR Proteomes; UP000264876; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR CDD; cd17359; MFS_XylE_like; 1.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 2.
DR InterPro; IPR020846; MFS_dom.
DR InterPro; IPR005828; MFS_sugar_transport-like.
DR InterPro; IPR036259; MFS_trans_sf.
DR InterPro; IPR003663; Sugar/inositol_transpt.
DR InterPro; IPR005829; Sugar_transporter_CS.
DR InterPro; IPR047984; XylE-like.
DR NCBIfam; TIGR00879; SP; 1.
DR PANTHER; PTHR48020:SF12; MFS DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR48020; PROTON MYO-INOSITOL COTRANSPORTER; 1.
DR Pfam; PF00083; Sugar_tr; 1.
DR PRINTS; PR00171; SUGRTRNSPORT.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
DR PROSITE; PS50850; MFS; 1.
DR PROSITE; PS00216; SUGAR_TRANSPORT_1; 1.
DR PROSITE; PS00217; SUGAR_TRANSPORT_2; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000264876};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|RuleBase:RU003346}.
FT TRANSMEM 51..74
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 86..106
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 118..137
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 143..164
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 176..194
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 214..234
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 298..321
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 336..357
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 364..387
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 399..427
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 439..461
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 467..486
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 52..492
FT /note="Major facilitator superfamily (MFS) profile"
FT /evidence="ECO:0000259|PROSITE:PS50850"
SQ SEQUENCE 510 AA; 54172 MW; 68E4F9CD1023989A CRC64;
MLSVHNDACT PNVGESWSRV RLPVMEKRSE VSGATPRPPA SAKQLNRRVT ALAVAAAIGG
FLFGFDSSVI NGAVNSITKT FGIPEAASGI TVASALIGCA VGAYAGGRMA DRWGRIRVMF
IASILFFVSS IFAGLAFATW DFIIWRLVGG LGIGIASVIA PAYISEVSPQ AIRGRLGSFQ
QLAITLGIFA ALLSDQIFAV TAGSADAMLG PIPAWRWMFI VGVVPSVVYG VLALRLPESP
RYLAAEGRND EAREVLSQIV PTETVETSLH DINDAIETEA KLTKKSSIRG SRFGLQPIVW
IGIILAIFQQ FVGINVIFYY STTLWQAVGF KESDSFTIST ITSVVNVAVT FVAILLVDKV
GRRPMLLAGS IGMTVSLGFM AIAFSQADIV NGNPSLPGAW GIVALIAANL FVISFGATWG
PLMWVLLGEM FPPSIRAAAL GVGSAANWIA NFVVTVTFPV LSSVNLTLTY GIYALFALLS
FVFVLAKIKE TKGRSLEDMG KDAVTSTSRA
//
