ID A0A2R3JY86_9LACO Unreviewed; 339 AA.
AC A0A2R3JY86;
DT 20-JUN-2018, integrated into UniProtKB/TrEMBL.
DT 20-JUN-2018, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE RecName: Full=Maltose epimerase {ECO:0000256|PIRNR:PIRNR005096};
DE EC=5.1.3.21 {ECO:0000256|PIRNR:PIRNR005096};
GN ORFNames=C5Z26_10910 {ECO:0000313|EMBL:AVK64587.1};
OS Lactobacillus sp. CBA3606.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC Lactobacillus.
OX NCBI_TaxID=2099789 {ECO:0000313|EMBL:AVK64587.1, ECO:0000313|Proteomes:UP000238064};
RN [1] {ECO:0000313|EMBL:AVK64587.1, ECO:0000313|Proteomes:UP000238064}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBA3606 {ECO:0000313|EMBL:AVK64587.1,
RC ECO:0000313|Proteomes:UP000238064};
RA Jung M.Y.;
RT "Complete genome sequence of Lactobacillus sp. CBA3606.";
RL Submitted (FEB-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Catalyzes the interconversion of alpha and beta anomers of
CC maltose. {ECO:0000256|PIRNR:PIRNR005096}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=alpha-D-glucose = beta-D-glucose; Xref=Rhea:RHEA:10264,
CC ChEBI:CHEBI:15903, ChEBI:CHEBI:17925; EC=5.1.3.3;
CC Evidence={ECO:0000256|ARBA:ARBA00001614};
CC -!- CATALYTIC ACTIVITY:
CC Reaction=alpha-maltose = beta-maltose; Xref=Rhea:RHEA:21228,
CC ChEBI:CHEBI:18147, ChEBI:CHEBI:18167; EC=5.1.3.21;
CC Evidence={ECO:0000256|PIRNR:PIRNR005096};
CC -!- PATHWAY: Carbohydrate metabolism; hexose metabolism.
CC {ECO:0000256|ARBA:ARBA00005028, ECO:0000256|PIRNR:PIRNR005096}.
CC -!- SIMILARITY: Belongs to the aldose epimerase family.
CC {ECO:0000256|ARBA:ARBA00006206, ECO:0000256|PIRNR:PIRNR005096}.
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DR EMBL; CP027194; AVK64587.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2R3JY86; -.
DR OrthoDB; 9779408at2; -.
DR UniPathway; UPA00242; -.
DR Proteomes; UP000238064; Chromosome.
DR GO; GO:0004034; F:aldose 1-epimerase activity; IEA:UniProtKB-EC.
DR GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR GO; GO:0050558; F:maltose epimerase activity; IEA:UniProtKB-EC.
DR GO; GO:0019318; P:hexose metabolic process; IEA:UniProtKB-UniPathway.
DR CDD; cd09019; galactose_mutarotase_like; 1.
DR Gene3D; 2.70.98.10; -; 1.
DR InterPro; IPR018052; Ald1_epimerase_CS.
DR InterPro; IPR015443; Aldose_1-epimerase.
DR InterPro; IPR008183; Aldose_1/G6P_1-epimerase.
DR InterPro; IPR011013; Gal_mutarotase_sf_dom.
DR InterPro; IPR047215; Galactose_mutarotase-like.
DR InterPro; IPR014718; GH-type_carb-bd.
DR PANTHER; PTHR10091:SF50; ALDOSE 1-EPIMERASE; 1.
DR PANTHER; PTHR10091; ALDOSE-1-EPIMERASE; 1.
DR Pfam; PF01263; Aldose_epim; 1.
DR PIRSF; PIRSF005096; GALM; 1.
DR SUPFAM; SSF74650; Galactose mutarotase-like; 1.
DR PROSITE; PS00545; ALDOSE_1_EPIMERASE; 1.
PE 3: Inferred from homology;
KW Carbohydrate metabolism {ECO:0000256|PIRNR:PIRNR005096};
KW Isomerase {ECO:0000256|ARBA:ARBA00023235, ECO:0000256|PIRNR:PIRNR005096}.
FT BINDING 172..174
FT /ligand="beta-D-galactose"
FT /ligand_id="ChEBI:CHEBI:27667"
FT /evidence="ECO:0000256|PIRSR:PIRSR005096-3"
SQ SEQUENCE 339 AA; 38058 MW; AFA8260773015A91 CRC64;
MKIIEHQANG INYYTLVNNH HMSVTIMDWG ATITAIKTHD KAGQFANVIL GFDAGEDYIN
YQSFFGATVA RVAGVIKNAT WRHHELTQNF GEHHLNGGNM PQIAFEPWFL ERKLQTADQV
GLVMQYITLD GENGYPGTMT ITANFILDNN GKFTISYTGK SDKATLFNPT NHTYFNLSGN
ADRLIDHQVL KINADEYSAL NKHGLPTGKL PWVTNTPFDF RKRTEIGPQI KKINGGLHHG
FVLNTTPHPQ VELLDRISGR KVTLKTNAKA IVVSSATNYR DDRYRLNGGK PMRSQLGLSL
QAQMLPDAIH HKEFGNIIIE PNVPVTYQTA YQFSNIYDV
//
