ID A0A2R4C9B6_9BURK Unreviewed; 398 AA.
AC A0A2R4C9B6;
DT 20-JUN-2018, integrated into UniProtKB/TrEMBL.
DT 20-JUN-2018, sequence version 1.
DT 24-JAN-2024, entry version 18.
DE SubName: Full=Heme biosynthesis protein HemY {ECO:0000313|EMBL:AVR96229.1};
GN ORFNames=C9I28_11300 {ECO:0000313|EMBL:AVR96229.1};
OS Pseudoduganella armeniaca.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Oxalobacteraceae; Telluria group; Pseudoduganella.
OX NCBI_TaxID=2072590 {ECO:0000313|EMBL:AVR96229.1, ECO:0000313|Proteomes:UP000240505};
RN [1] {ECO:0000313|EMBL:AVR96229.1, ECO:0000313|Proteomes:UP000240505}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ZMN-3 {ECO:0000313|EMBL:AVR96229.1,
RC ECO:0000313|Proteomes:UP000240505};
RA Huang H., Ren M.;
RT "Massilia armeniaca sp. nov., isolated from desert soil.";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Involved in a late step of protoheme IX synthesis.
CC {ECO:0000256|ARBA:ARBA00002962}.
CC -!- PATHWAY: Porphyrin-containing compound metabolism; protoheme
CC biosynthesis. {ECO:0000256|ARBA:ARBA00004744}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane
CC {ECO:0000256|ARBA:ARBA00004429}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004429}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP028324; AVR96229.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2R4C9B6; -.
DR KEGG; masz:C9I28_11300; -.
DR OrthoDB; 7053339at2; -.
DR UniPathway; UPA00252; -.
DR Proteomes; UP000240505; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0042168; P:heme metabolic process; IEA:InterPro.
DR GO; GO:0006779; P:porphyrin-containing compound biosynthetic process; IEA:UniProtKB-KW.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR InterPro; IPR005254; Heme_biosyn_assoc_TPR_pro.
DR InterPro; IPR010817; HemY_N.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR NCBIfam; TIGR00540; TPR_hemY_coli; 1.
DR Pfam; PF07219; HemY_N; 1.
DR SUPFAM; SSF48452; TPR-like; 1.
PE 4: Predicted;
KW Cell inner membrane {ECO:0000256|ARBA:ARBA00022519};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Porphyrin biosynthesis {ECO:0000256|ARBA:ARBA00023244};
KW Reference proteome {ECO:0000313|Proteomes:UP000240505};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 39..58
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 26..131
FT /note="HemY N-terminal"
FT /evidence="ECO:0000259|Pfam:PF07219"
SQ SEQUENCE 398 AA; 44499 MW; E4166E881726291D CRC64;
MRLFLWLLAL MAAAIGIAVT ARFNPGNVVL FYPPYRMDLS LNFFVVLMVA LFLLLYAVTR
AVRATMRMPA RVAEYRQRKR ERDGNKGLRD ALKALFEGRF GHAEKAALRA AELPENAGVA
ALIGARAAHR MRQQARRDQW VARIADDPAM KTARLMTMTE LLVDDHQPEA ALAAVRELNA
SGTRHIHALQ WSLKAEQQAK NWPEVLRLVR SLDKHKALHP ALSARLRELA YNDLLSNKAH
DAESLMRVWS TIPSNDRVKP VVACRAATAL NARGLHDEAR LVAEESLKAN WDERVIRAYR
DAAAPAGSGA LLAQIEHCEA WLLERPNDAE LALTLGSLCL KQKLWGKAQR YLEQALSDAT
DPPMVREAHL KLAQLHEALQ QPEAAANHYR QCALATIL
//
