ID A0A2R4CD21_9BURK Unreviewed; 1160 AA.
AC A0A2R4CD21;
DT 20-JUN-2018, integrated into UniProtKB/TrEMBL.
DT 20-JUN-2018, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=C9I28_19050 {ECO:0000313|EMBL:AVR97506.1};
OS Pseudoduganella armeniaca.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Oxalobacteraceae; Telluria group; Pseudoduganella.
OX NCBI_TaxID=2072590 {ECO:0000313|EMBL:AVR97506.1, ECO:0000313|Proteomes:UP000240505};
RN [1] {ECO:0000313|EMBL:AVR97506.1, ECO:0000313|Proteomes:UP000240505}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ZMN-3 {ECO:0000313|EMBL:AVR97506.1,
RC ECO:0000313|Proteomes:UP000240505};
RA Huang H., Ren M.;
RT "Massilia armeniaca sp. nov., isolated from desert soil.";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- SUBCELLULAR LOCATION: Cell inner membrane
CC {ECO:0000256|ARBA:ARBA00004429}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004429}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CP028324; AVR97506.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2R4CD21; -.
DR KEGG; masz:C9I28_19050; -.
DR OrthoDB; 5290456at2; -.
DR Proteomes; UP000240505; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd16922; HATPase_EvgS-ArcB-TorS-like; 1.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd17546; REC_hyHK_CKI1_RcsC-like; 2.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 2.60.40.2380; -; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 1.20.120.160; HPT domain; 1.
DR InterPro; IPR011623; 7TMR_DISM_rcpt_extracell_dom1.
DR InterPro; IPR011622; 7TMR_DISM_rcpt_extracell_dom2.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR036641; HPT_dom_sf.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR008207; Sig_transdc_His_kin_Hpt_dom.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR PANTHER; PTHR45339; HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE J; 1.
DR PANTHER; PTHR45339:SF1; HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE J; 1.
DR Pfam; PF07695; 7TMR-DISM_7TM; 1.
DR Pfam; PF07696; 7TMR-DISMED2; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF01627; Hpt; 1.
DR Pfam; PF00072; Response_reg; 2.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00448; REC; 2.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF52172; CheY-like; 2.
DR SUPFAM; SSF47226; Histidine-containing phosphotransfer domain, HPT domain; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50894; HPT; 1.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 2.
PE 4: Predicted;
KW Cell inner membrane {ECO:0000256|ARBA:ARBA00022519};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553, ECO:0000256|PROSITE-
KW ProRule:PRU00169}; Reference proteome {ECO:0000313|Proteomes:UP000240505};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..35
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 36..1160
FT /note="histidine kinase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5015347249"
FT TRANSMEM 199..219
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 231..253
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 265..283
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 295..314
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 320..340
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 352..371
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 427..648
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT DOMAIN 666..788
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
FT DOMAIN 817..933
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
FT DOMAIN 978..1079
FT /note="HPt"
FT /evidence="ECO:0000259|PROSITE:PS50894"
FT MOD_RES 720
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
FT MOD_RES 866
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
FT MOD_RES 1017
FT /note="Phosphohistidine"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00110"
SQ SEQUENCE 1160 AA; 123324 MW; 313689A92BBB4A9C CRC64;
MTRAAAHRPL APFVTVLCAL CCWLGGLLLA QAAVAAPTPL VVDPNVGAID AWPALTVLDD
PRGELTPAQA LAAADRFEPP RTANATLGVE PHLVWLRIPI VVPPGGDTHR VLAIDYALLN
RVDVYLATGS AIVAHPPAGN MLPAGQRGLS GRVPAVSLHL TPGASHTILV RAQTSAPILL
PIQLYTPEGF HAAALDEHML QGLMLGLGLC LLLYSLAQWA NLREPLFGKY ALLVGGITLY
SADFFGIGAQ YLWPGNAWMT QHAGGLLSLA ASCGAYLFVQ QALARPGMDR VYSRLMRIGA
ALCVLTAIGF AFDLVDVETL VLFISTLGIM PMLLGLPKAF ARARRGDTVG SYFLVGWSIS
FVSSVILTLV FKGLLGANFW TMHALQFGST IDMLLFMRIL GLRTKAMQNA MLRAEEATRM
KSDFLANMSH EIRTPMNAII GMSRLALMAD PNPKQRNYLD KILGAGEHLL GIINDILDFS
KIEAGKLVLE AVPFDLNELF DHLSNLTAIK TDARRVELVF RIGRGIPGRL VGDPLRLGQV
LINLTNNAVK FTEEGEIVVA VSVVQRAPGT IVLRFSVTDT GIGMNEEQLA RLFQSFSQAD
TSITRKYGGT GLGLSISQQL VELMGGRIKV ASTPGTGSQF SFSVPLGVAD PGQQPVTPSA
PLHNARVMVV DDSTTAREAL VEMLGSLGVH ATGIESGEAA LAELAAAMLA GNPYQVVLMD
YMMPGWDGVE TIRRIRSDRR FAAPPAILMI SAATRDAVLQ QEGLVPMNGF LHKPVGPALL
YHTLLQVLRP ELAEPGEVGR AQAPSARLDL SRLDGARILL VEDNANNREV ALDFLAAARM
QVDVAVHGAD AVRMVAEGDY DLVLMDIQMH VMDGLTATRE IRATIGAREL PIVAMTAHAM
AGDRERSLAA GMNDHITKPI DPDQLFRTLL KWIPPGRLAG RSLAALPAAD LPDAGATAAL
PVIGGVDWAR AGTGGDQWQA RLFKRIRSFR GEYGGAAAQV REALAAGTPA ALQALAHNLK
ASAAYIGAWR VAGLADQLEQ ELRGPARNER ALALAGELAD ALEPLLAGLA GLAQVEPPAP
AAPARADAGD LIRLLAGYLR SDDARAEDAV QALQALLADS PHGGLLATVA RAIDDIEYDA
ALAPLAALAQ ALDVNMEENA
//
