ID A0A2R4CGX9_9BURK Unreviewed; 382 AA.
AC A0A2R4CGX9;
DT 20-JUN-2018, integrated into UniProtKB/TrEMBL.
DT 20-JUN-2018, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE RecName: Full=glucarate dehydratase {ECO:0000256|ARBA:ARBA00011973};
DE EC=4.2.1.40 {ECO:0000256|ARBA:ARBA00011973};
GN ORFNames=C9I28_27300 {ECO:0000313|EMBL:AVR98913.1};
OS Pseudoduganella armeniaca.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Oxalobacteraceae; Telluria group; Pseudoduganella.
OX NCBI_TaxID=2072590 {ECO:0000313|EMBL:AVR98913.1, ECO:0000313|Proteomes:UP000240505};
RN [1] {ECO:0000313|EMBL:AVR98913.1, ECO:0000313|Proteomes:UP000240505}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ZMN-3 {ECO:0000313|EMBL:AVR98913.1,
RC ECO:0000313|Proteomes:UP000240505};
RA Huang H., Ren M.;
RT "Massilia armeniaca sp. nov., isolated from desert soil.";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=D-glucarate = 5-dehydro-4-deoxy-D-glucarate + H2O;
CC Xref=Rhea:RHEA:14573, ChEBI:CHEBI:15377, ChEBI:CHEBI:30612,
CC ChEBI:CHEBI:42819; EC=4.2.1.40;
CC Evidence={ECO:0000256|ARBA:ARBA00001426};
CC -!- PATHWAY: Carbohydrate acid metabolism; D-glucarate degradation; 2,5-
CC dioxopentanoate from D-glucarate: step 1/2.
CC {ECO:0000256|ARBA:ARBA00005183}.
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DR EMBL; CP028324; AVR98913.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2R4CGX9; -.
DR KEGG; masz:C9I28_27300; -.
DR OrthoDB; 5596677at2; -.
DR Proteomes; UP000240505; Chromosome.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR Gene3D; 3.20.20.120; Enolase-like C-terminal domain; 1.
DR Gene3D; 3.30.390.10; Enolase-like, N-terminal domain; 1.
DR InterPro; IPR034593; DgoD-like.
DR InterPro; IPR036849; Enolase-like_C_sf.
DR InterPro; IPR029017; Enolase-like_N.
DR InterPro; IPR029065; Enolase_C-like.
DR InterPro; IPR013342; Mandelate_racemase_C.
DR PANTHER; PTHR48080; D-GALACTONATE DEHYDRATASE-RELATED; 1.
DR PANTHER; PTHR48080:SF4; GLUCARATE DEHYDRATASE; 1.
DR Pfam; PF13378; MR_MLE_C; 1.
DR SMART; SM00922; MR_MLE; 1.
DR SUPFAM; SSF51604; Enolase C-terminal domain-like; 1.
DR SUPFAM; SSF54826; Enolase N-terminal domain-like; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000240505}.
FT DOMAIN 149..245
FT /note="Mandelate racemase/muconate lactonizing enzyme C-
FT terminal"
FT /evidence="ECO:0000259|SMART:SM00922"
SQ SEQUENCE 382 AA; 42547 MW; 6CBCB9E5FF4ABC04 CRC64;
MTDKIIITKL HFDEVVVPTH EGAINSSSLP KPLHRQPVDG KKAWGVQFDE LPKLIVTMTL
SNGVVGYGEF YRDHDWPTVK NIAQGLIGLA IDDLTLQALP IGLCREHYGF ECVIWDAYAK
CKGMRVVDLL GGPIRTKVEV SAWSSHRTLE DIGPVAKRFQ DMGYKVLKLK ADLEDNVPEL
CARIKEAAPG LKLIFDPNMR WKNLGYVRPL ARALEEVGNV LLLEDPMPHW MLMQGADLRK
FTSIPIVLHV SPPYEQEGQA IHDAINALMH GAVDGFNFNA GLDSFRQLDG IAAAAGVNCW
HGSEIDLGIL EAMFIHNACA AKSCVWPSDI FGRLLRQHDL LRTPHRIDAP YAYLPEGPGL
GVEVDREAIE RYKIGEYTVT QD
//
