ID   A0A2R4SZ17_9ACTN        Unreviewed;       942 AA.
AC   A0A2R4SZ17;
DT   20-JUN-2018, integrated into UniProtKB/TrEMBL.
DT   20-JUN-2018, sequence version 1.
DT   24-JAN-2024, entry version 22.
DE   SubName: Full=RNA helicase {ECO:0000313|EMBL:AVZ72084.1};
GN   ORFNames=SLUN_07605 {ECO:0000313|EMBL:AVZ72084.1};
OS   Streptomyces lunaelactis.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=1535768 {ECO:0000313|EMBL:AVZ72084.1, ECO:0000313|Proteomes:UP000244201};
RN   [1] {ECO:0000313|EMBL:AVZ72084.1, ECO:0000313|Proteomes:UP000244201}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MM109 {ECO:0000313|EMBL:AVZ72084.1,
RC   ECO:0000313|Proteomes:UP000244201};
RA   Naome A., Martinet L., Maciejewska M., Anderssen S., Adam D., Tenconi E.,
RA   Deflandre B., Arguelles-Arias A., Calusinska M., Copieters W., Karim L.,
RA   Hanikenne M., Baurain D., van Wezel G., Smargiasso N., de Pauw E.,
RA   Delfosse P., Rigali S.;
RT   "Complete genome sequence of Streptomyces lunaelactis MM109T, a Ferroverdin
RT   A producer isolated from cave moonmilk deposits.";
RL   Submitted (JAN-2018) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; CP026304; AVZ72084.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2R4SZ17; -.
DR   KEGG; slk:SLUN_07605; -.
DR   OrthoDB; 3229913at2; -.
DR   Proteomes; UP000244201; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   CDD; cd18795; SF2_C_Ski2; 1.
DR   Gene3D; 1.10.3380.30; -; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR   InterPro; IPR014001; Helicase_ATP-bd.
DR   InterPro; IPR001650; Helicase_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR012961; Ski2/MTR4_C.
DR   PANTHER; PTHR12131; ATP-DEPENDENT RNA AND DNA HELICASE; 1.
DR   PANTHER; PTHR12131:SF8; HELICASE SKI2W; 1.
DR   Pfam; PF00270; DEAD; 1.
DR   Pfam; PF08148; DSHCT; 1.
DR   Pfam; PF00271; Helicase_C; 1.
DR   SMART; SM00487; DEXDc; 1.
DR   SMART; SM01142; DSHCT; 1.
DR   SMART; SM00490; HELICc; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR   PROSITE; PS51194; HELICASE_CTER; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000313|EMBL:AVZ72084.1};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000244201}.
FT   DOMAIN          44..202
FT                   /note="Helicase ATP-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51192"
FT   DOMAIN          330..493
FT                   /note="Helicase C-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS51194"
FT   REGION          654..692
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        671..692
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   942 AA;  105235 MW;  F9B70A520FCF178E CRC64;
     MTEDLSPAER YAAARVRAAD EATALAPFRA LYEFDLDPFQ IEACQALEAG KGVLVAAPTG
     SGKTIVGEFA VHLALQQGRK CFYTTPIKAL SNQKYTDLAK RYGADKVGLL TGDNSINSEA
     PVVVMTTEVL RNMLYAGSQS LLGLGYVVMD EVHYLSDRFR GAVWEEVIIH LPESVTLVSL
     SATVSNAEEF GDWLDTVRGD TEVIVSEHRP VPLWQHVMAG RRMYDVFEEE TDHGGRGSGR
     REVNPDLVRL ARMENQRTYN PKDRRRGKMV READRERERR QRGRIWTPGR PEVIERLDAD
     GLLPAITFIF SRAGCEAAVQ QCMYAGLRLN DEDARQRVRE IVEERTASIP GEDLHVLGYY
     EWLEGLERGI AAHHAGMLPT FKEVVEELFV RGLVKAVFAT ETLALGINMP ARSVVLEKLV
     KWNGEQHADI TPGEYTQLTG RAGRRGIDVE GHAVVLWQRG MDPVALAGLA GTRTYPLRSS
     FRPSYNMAVN LVQQFGRHRS RELLETSFAQ FQADKSVVGI SRQVQRNEEG LEGYREGMTC
     HLGDFEEYAR LRRELKDRET ELAKQGVAQR RAAAAASLEK LKPGDIIHVP TGKFAGLALV
     LDPGIPAGRS NGHRGFEQHD GPRPLVLTSE RQVKRLASMD FPVPVEPLER MRIPKSFNPR
     SPQSRRDLAS ALRTKAGHIE PERHRKGRAA AADDREIARL RTELRAHPCH GCDEREDHAR
     WAERYHRLQR DTQQLERRIE GRTNTIARTF DRIVALLTEL DYLRVDEVTE HGRRLARLYG
     ELDLLASECL RDGVWEGLSP AELAACVSAL VYEARQSDDA VAPKVPAGKA KTALGEMVHI
     WGRLDALEEE FKINQAEGVG QREPDLGFAW AAYQWASDRG LDEVLREAEM PAGDFVRWCK
     QVIDVLGQIA AAAPREGSTV AKNARKAVDA LLRGVVAYSS VG
//