ID A0A2R4T2Y3_9ACTN Unreviewed; 721 AA.
AC A0A2R4T2Y3;
DT 20-JUN-2018, integrated into UniProtKB/TrEMBL.
DT 20-JUN-2018, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE RecName: Full=SSD domain-containing protein {ECO:0000259|PROSITE:PS50156};
GN ORFNames=SLUN_16300 {ECO:0000313|EMBL:AVZ73509.1};
OS Streptomyces lunaelactis.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1535768 {ECO:0000313|EMBL:AVZ73509.1, ECO:0000313|Proteomes:UP000244201};
RN [1] {ECO:0000313|EMBL:AVZ73509.1, ECO:0000313|Proteomes:UP000244201}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MM109 {ECO:0000313|EMBL:AVZ73509.1,
RC ECO:0000313|Proteomes:UP000244201};
RA Naome A., Martinet L., Maciejewska M., Anderssen S., Adam D., Tenconi E.,
RA Deflandre B., Arguelles-Arias A., Calusinska M., Copieters W., Karim L.,
RA Hanikenne M., Baurain D., van Wezel G., Smargiasso N., de Pauw E.,
RA Delfosse P., Rigali S.;
RT "Complete genome sequence of Streptomyces lunaelactis MM109T, a Ferroverdin
RT A producer isolated from cave moonmilk deposits.";
RL Submitted (JAN-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP026304; AVZ73509.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2R4T2Y3; -.
DR KEGG; slk:SLUN_16300; -.
DR OrthoDB; 7051771at2; -.
DR Proteomes; UP000244201; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR InterPro; IPR004869; MMPL_dom.
DR InterPro; IPR000731; SSD.
DR PANTHER; PTHR33406; MEMBRANE PROTEIN MJ1562-RELATED; 1.
DR PANTHER; PTHR33406:SF2; MEMBRANE PROTEIN SCO6666-RELATED; 1.
DR Pfam; PF03176; MMPL; 2.
DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR PROSITE; PS50156; SSD; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000244201};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..37
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 38..721
FT /note="SSD domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5015358124"
FT TRANSMEM 180..200
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 207..225
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 231..251
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 272..298
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 304..331
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 364..382
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 508..527
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 539..560
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 572..591
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 623..642
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 648..676
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 197..329
FT /note="SSD"
FT /evidence="ECO:0000259|PROSITE:PS50156"
SQ SEQUENCE 721 AA; 75013 MW; 1419E6A59DA9E1E4 CRC64;
MATFLYKLGR FAFRRRRLVA LLWVALLALA GVGAASASTA TSSSFSVPGT EAQKAFDLLE
ERFPGASPDG ATANVVFQAP DGRKMTEPAS KAEVNKAVAE LKAGSDQIAS VTDPYTANAV
SKNGGTAYIS VSYKVSSMEL TDETREALEK TGTAARDAGL TVEIGGDALQ AVPETGAGEI
IGVGIAAVVL VITFGSLVAA GLPLLTAIIG VGIGISTITA LANVLDLGST TSTLAMMIGL
AVGIDYALFI VSRYRAELAE GRSREEAAGR AVGTAGSAVV FAGLTVVIAL VGLAVVNIPM
LTKMGFAAAG TVVIAVLIAL TLIPALLGFA GKRVLGRKAR KGQPAGDKPN MGTRWARFVL
RRPVMVLLVG VIGLGAIALP AASLELGLPD DGSQPVSTTQ RKAYDTLSDG FGPGFNGPLL
VVVDGDKGAA DRTVTEIKGL DGVAAVTPPT LNKAGDTAMI TVIPKDRPSS AETESLVHSI
RADSGDDVLI TGATAMNIDF SQKMNDALLP YLALVVGLAF LLLMVVFRSV LVPLKAALGF
LLSVVAALGA VVAVFQWGWL GSLLGVEQTG PIMSMMPIFM VGVVFGLAMD YEVFLVTRMR
EAYVHGERPG EAIVTGFKHG ARVVTAAAVI MMAVFSGFIG SSEQMIKMIG FGLAIAVLFD
AFVVRMAIVP AVLALLGHKA WWLPRWLDRL LPNVDVEGEQ LRKELAVGPE DPDAERELVR
V
//
