ID A0A2R4T8M4_9ACTN Unreviewed; 1012 AA.
AC A0A2R4T8M4;
DT 20-JUN-2018, integrated into UniProtKB/TrEMBL.
DT 20-JUN-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=HTH luxR-type domain-containing protein {ECO:0000259|PROSITE:PS50043};
GN ORFNames=SLUN_27885 {ECO:0000313|EMBL:AVZ75457.1};
OS Streptomyces lunaelactis.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1535768 {ECO:0000313|EMBL:AVZ75457.1, ECO:0000313|Proteomes:UP000244201};
RN [1] {ECO:0000313|EMBL:AVZ75457.1, ECO:0000313|Proteomes:UP000244201}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MM109 {ECO:0000313|EMBL:AVZ75457.1,
RC ECO:0000313|Proteomes:UP000244201};
RA Naome A., Martinet L., Maciejewska M., Anderssen S., Adam D., Tenconi E.,
RA Deflandre B., Arguelles-Arias A., Calusinska M., Copieters W., Karim L.,
RA Hanikenne M., Baurain D., van Wezel G., Smargiasso N., de Pauw E.,
RA Delfosse P., Rigali S.;
RT "Complete genome sequence of Streptomyces lunaelactis MM109T, a Ferroverdin
RT A producer isolated from cave moonmilk deposits.";
RL Submitted (JAN-2018) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP026304; AVZ75457.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2R4T8M4; -.
DR KEGG; slk:SLUN_27885; -.
DR OrthoDB; 5476461at2; -.
DR Proteomes; UP000244201; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd06170; LuxR_C_like; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR041664; AAA_16.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR016032; Sig_transdc_resp-reg_C-effctor.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR000792; Tscrpt_reg_LuxR_C.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR16305; TESTICULAR SOLUBLE ADENYLYL CYCLASE; 1.
DR PANTHER; PTHR16305:SF35; TRANSCRIPTIONAL ACTIVATOR DOMAIN; 1.
DR Pfam; PF13191; AAA_16; 1.
DR Pfam; PF00196; GerE; 1.
DR PRINTS; PR00038; HTHLUXR.
DR SMART; SM00421; HTH_LUXR; 1.
DR SUPFAM; SSF46894; C-terminal effector domain of the bipartite response regulators; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF48452; TPR-like; 1.
DR PROSITE; PS50043; HTH_LUXR_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000244201}.
FT DOMAIN 933..998
FT /note="HTH luxR-type"
FT /evidence="ECO:0000259|PROSITE:PS50043"
SQ SEQUENCE 1012 AA; 110176 MW; E85CB32F4C253818 CRC64;
MLGDVETRSV SPVFVGRAGE LAKLTDALAR ATAGEPQALL LGGEAGVGKT RLVEEMLAEA
CRREVVVAVG GCVEIGADGL PFAPFSTALR ALHRQLPKEL AAAAAGQEDE LARLLPELGE
TTRREHTQHD EEDMARLFEL TARLLERIAA DRTVVLVLED LHWSDASTRH LLAYLFRTLR
RGRLVVIATY RSDDVHRRHP LRPFLAELDR MRTVQRIELT RFNRGEVRRQ MAGILSADPQ
PAMVDRVFER SDGNAFFVEE LACSITEDCP TGLPDSLRDI LLVRVEALPE DAQRAARIVA
EGGSTVEYGL LLAVARLGED DLIEALRAAV GANILLATPD GDGYRFRHSL AREAVSDDLL
PGERSRLNRH YAQALEADPW LVREDERAMR LATYWYHAHD AAKALPAVLS ASVEARRRHA
YSEQLRLLGR AMELWDNAPD EVRAELRPVD YAEVYPPCGC DPETTPLRYL DLMAEASVAG
RLSGEREHAL KITKRGQRLA EAEGDALRTA WFSVQRSRLV SSLGRGDGWA ELGTAQELVR
GLPPSAVHAE VLAEAASWGM VHDPGPGSLA TAERAVEYAR MVGEEDIELR ARLTLGSLMV
DAGDVEGGLA EMYAVKGEAV SLDLPAHVGR THVNLPSVLE GVGRSQEAVG ILTEGIELSR
TYGLLDTEAW ICDNLAESYV SLGRWDEAAR SAERALRIAL SPKPRGYGAM RCAYLSLARG
DTAKAAEHLE AARDHFGKND PMPQCFLPLG TIALCIAAVQ GRVLDARAEF ERAAAEGFPP
GTQRYAWPLL RAAAALEADT RGLPAAEPGR AEALERIRKA TRGLVTAVPV WSAHERWVRA
ELLRAGGEDT PLDWAEAGTA FEQVDRPYDL ARVRHRWAEA LLQSDRAQAA GLLRQAHATA
QQLGARPLAE DVALLAQRAR IALTDDPPSA AAAAGPALGL TRREEDVLRL VAAGRSNRLI
AEELYISPKT ASVHVSNILA KLGVSGRGEA AAMAHRLRLF PPSGEGRREA SA
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