ID A0A2R4WXM6_9EURY Unreviewed; 372 AA.
AC A0A2R4WXM6;
DT 20-JUN-2018, integrated into UniProtKB/TrEMBL.
DT 20-JUN-2018, sequence version 1.
DT 24-JAN-2024, entry version 18.
DE SubName: Full=tRNA (N6-threonylcarbamoyladenosine(37)-N6)-methyltransferase TrmO {ECO:0000313|EMBL:AWB26293.1};
GN Name=tsaA {ECO:0000313|EMBL:AWB26293.1};
GN ORFNames=HARCEL1_00445 {ECO:0000313|EMBL:AWB26293.1};
OS Halococcoides cellulosivorans.
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Halobacteriales;
OC Haloarculaceae; Halococcoides.
OX NCBI_TaxID=1679096 {ECO:0000313|EMBL:AWB26293.1, ECO:0000313|Proteomes:UP000244727};
RN [1] {ECO:0000313|EMBL:AWB26293.1, ECO:0000313|Proteomes:UP000244727}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HArcel1 {ECO:0000313|EMBL:AWB26293.1,
RC ECO:0000313|Proteomes:UP000244727};
RA Sorokin D.Y., Toshchakov S.V., Samarov N.I., Korzhenkov A., Kublanov I.V.;
RT "Halococcoides cellulosivorans gen. nov., sp. nov., an extremely halophilic
RT cellulose-utilizing haloarchaeon from hypersaline lakes.";
RL Submitted (APR-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the tRNA methyltransferase O family.
CC {ECO:0000256|ARBA:ARBA00033753}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP028858; AWB26293.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2R4WXM6; -.
DR KEGG; harc:HARCEL1_00445; -.
DR Proteomes; UP000244727; Chromosome.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR CDD; cd09281; UPF0066; 1.
DR Gene3D; 3.30.1330.130; -; 1.
DR Gene3D; 2.40.30.70; YaeB-like; 1.
DR InterPro; IPR003814; FmdEsu_dom.
DR InterPro; IPR023370; TrmO-like_N.
DR InterPro; IPR036413; YaeB-like_sf.
DR InterPro; IPR036414; YaeB_N_sf.
DR InterPro; IPR000962; Znf_DskA_TraR.
DR NCBIfam; TIGR00104; tRNA_TsaA; 1.
DR PANTHER; PTHR39418; DEHYDROGENASE-RELATED; 1.
DR PANTHER; PTHR39418:SF1; DEHYDROGENASE-RELATED; 1.
DR Pfam; PF02663; FmdE; 1.
DR Pfam; PF01980; TrmO; 1.
DR Pfam; PF01258; zf-dskA_traR; 1.
DR SUPFAM; SSF143555; FwdE-like; 1.
DR SUPFAM; SSF118196; YaeB-like; 1.
DR PROSITE; PS51668; TSAA_2; 1.
PE 3: Inferred from homology;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Methyltransferase {ECO:0000313|EMBL:AWB26293.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000244727};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000313|EMBL:AWB26293.1};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 5..131
FT /note="TsaA-like"
FT /evidence="ECO:0000259|PROSITE:PS51668"
FT REGION 122..141
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 125..141
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 372 AA; 40756 MW; 35DF28EA54F533B6 CRC64;
MFEAITQIGT VHSAFDEPSD PETMREREST IVIDEAYSDG LYRIEDSDHL VVVFYIHEAD
APTLRGPRRY GVERGTFASR SPHRPSPIGT TTVELLERDG RELLVRGLDA IDGTPVLDLK
PYAPSLDRPT RETDRRADPR GHVERAIADR DREAVLLEAG GIHGHYCPYL ALGVMAGVHA
MRELGATSDG FEDLIAVTET NSCFADGVQV ATGCTVGNNA LVYRDLGKTA MTLVRRSAPD
AGVRVHVKER EAIVERDYPE ANALFERVIA DGEGTDADRE RLAERWAEVA FDLLDRPIGE
LCDIQTGVAV DLPDPAPIYE DAICAACGES VMAPKTVERD AERFCRACAG AEYHQLDGRG
CSWIESDRVG SS
//
