ID A0A2R6PB16_ACTCC Unreviewed; 260 AA.
AC A0A2R6PB16;
DT 20-JUN-2018, integrated into UniProtKB/TrEMBL.
DT 20-JUN-2018, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE RecName: Full=Peptidyl-prolyl cis-trans isomerase {ECO:0000256|RuleBase:RU363019};
DE Short=PPIase {ECO:0000256|RuleBase:RU363019};
DE EC=5.2.1.8 {ECO:0000256|RuleBase:RU363019};
GN ORFNames=CEY00_Acc31233 {ECO:0000313|EMBL:PSR88203.1};
OS Actinidia chinensis var. chinensis (Chinese soft-hair kiwi).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; Ericales; Actinidiaceae; Actinidia.
OX NCBI_TaxID=1590841 {ECO:0000313|EMBL:PSR88203.1, ECO:0000313|Proteomes:UP000241394};
RN [1] {ECO:0000313|EMBL:PSR88203.1, ECO:0000313|Proteomes:UP000241394}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Red5 {ECO:0000313|Proteomes:UP000241394};
RC TISSUE=Young leaf {ECO:0000313|EMBL:PSR88203.1};
RA Pilkington S., Crowhurst R., Hilario E., Nardozza S., Fraser L., Peng Y.,
RA Gunaseelan K., Simpson R., Tahir J., Deroles S., Templeton K., Luo Z.,
RA Davy M., Cheng C., Mcneilage M., Scaglione D., Liu Y., Zhang Q., Datson P.,
RA De Silva N., Gardiner S., Bassett H., Chagne D., Mccallum J., Dzierzon H.,
RA Deng C., Wang Y.-Y., Barron N., Manako K., Bowen J., Foster T., Erridge Z.,
RA Tiffin H., Waite C., Davies K., Grierson E., Laing W., Kirk R., Chen X.,
RA Wood M., Montefiori M., Brummell D., Schwinn K., Catanach A., Fullerton C.,
RA Li D., Meiyalaghan S., Nieuwenhuizen N., Read N., Prakash R., Hunter D.,
RA Zhang H., Mckenzie M., Knabel M., Harris A., Allan A., Chen A., Janssen B.,
RA Plunkett B., Dwamena C., Voogd C., Leif D., Lafferty D., Souleyre E.,
RA Varkonyi-Gasic E., Gambi F., Hanley J., Yao J.-L., Cheung J., David K.,
RA Warren B., Marsh K., Snowden K., Lin-Wang K., Brian L.,
RA Martinez-Sanchez M., Wang M., Ileperuma N., Macnee N., Campin R.,
RA Mcatee P., Drummond R., Espley R., Ireland H., Wu R., Atkinson R.,
RA Karunairetnam S., Bulley S., Chunkath S., Hanley Z., Storey R.,
RA Thrimawithana A., Thomson S., David C., Testolin R.;
RT "An improved, manually edited Actinidia chinensis var. chinensis
RT (kiwifruit) genome highlights the challenges associated with draft genomes
RT and gene prediction in plants.";
RL Submitted (JUL-2017) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000241394}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Red5 {ECO:0000313|Proteomes:UP000241394};
RX PubMed=29661190; DOI=10.1186/s12864-018-4656-3;
RA Pilkington S.M., Crowhurst R., Hilario E., Nardozza S., Fraser L., Peng Y.,
RA Gunaseelan K., Simpson R., Tahir J., Deroles S.C., Templeton K., Luo Z.,
RA Davy M., Cheng C., McNeilage M., Scaglione D., Liu Y., Zhang Q., Datson P.,
RA De Silva N., Gardiner S.E., Bassett H., Chagne D., McCallum J.,
RA Dzierzon H., Deng C., Wang Y.Y., Barron L., Manako K., Bowen J.,
RA Foster T.M., Erridge Z.A., Tiffin H., Waite C.N., Davies K.M.,
RA Grierson E.P., Laing W.A., Kirk R., Chen X., Wood M., Montefiori M.,
RA Brummell D.A., Schwinn K.E., Catanach A., Fullerton C., Li D.,
RA Meiyalaghan S., Nieuwenhuizen N., Read N., Prakash R., Hunter D., Zhang H.,
RA McKenzie M., Knabel M., Harris A., Allan A.C., Gleave A., Chen A.,
RA Janssen B.J., Plunkett B., Ampomah-Dwamena C., Voogd C., Leif D.,
RA Lafferty D., Souleyre E.J.F., Varkonyi-Gasic E., Gambi F., Hanley J.,
RA Yao J.L., Cheung J., David K.M., Warren B., Marsh K., Snowden K.C.,
RA Lin-Wang K., Brian L., Martinez-Sanchez M., Wang M., Ileperuma N.,
RA Macnee N., Campin R., McAtee P., Drummond R.S.M., Espley R.V.,
RA Ireland H.S., Wu R., Atkinson R.G., Karunairetnam S., Bulley S.,
RA Chunkath S., Hanley Z., Storey R., Thrimawithana A.H., Thomson S.,
RA David C., Testolin R., Huang H., Hellens R.P., Schaffer R.J.;
RT "A manually annotated Actinidia chinensis var. chinensis (kiwifruit) genome
RT highlights the challenges associated with draft genomes and gene prediction
RT in plants.";
RL BMC Genomics 19:257-257(2018).
CC -!- FUNCTION: PPIases accelerate the folding of proteins. It catalyzes the
CC cis-trans isomerization of proline imidic peptide bonds in
CC oligopeptides. {ECO:0000256|RuleBase:RU363019}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=[protein]-peptidylproline (omega=180) = [protein]-
CC peptidylproline (omega=0); Xref=Rhea:RHEA:16237, Rhea:RHEA-
CC COMP:10747, Rhea:RHEA-COMP:10748, ChEBI:CHEBI:83833,
CC ChEBI:CHEBI:83834; EC=5.2.1.8;
CC Evidence={ECO:0000256|RuleBase:RU363019};
CC -!- SIMILARITY: Belongs to the cyclophilin-type PPIase family.
CC {ECO:0000256|ARBA:ARBA00007365, ECO:0000256|RuleBase:RU363019}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PSR88203.1}.
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DR EMBL; NKQK01000027; PSR88203.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2R6PB16; -.
DR STRING; 1590841.A0A2R6PB16; -.
DR EnsemblPlants; PSR88203; PSR88203; CEY00_Acc31233.
DR Gramene; PSR88203; PSR88203; CEY00_Acc31233.
DR InParanoid; A0A2R6PB16; -.
DR Proteomes; UP000241394; Chromosome lg27.
DR GO; GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IEA:UniProtKB-UniRule.
DR Gene3D; 2.40.100.10; Cyclophilin-like; 1.
DR InterPro; IPR029000; Cyclophilin-like_dom_sf.
DR InterPro; IPR002130; Cyclophilin-type_PPIase_dom.
DR PANTHER; PTHR11071; PEPTIDYL-PROLYL CIS-TRANS ISOMERASE; 1.
DR PANTHER; PTHR11071:SF561; PEPTIDYL-PROLYL CIS-TRANS ISOMERASE H; 1.
DR Pfam; PF00160; Pro_isomerase; 1.
DR PRINTS; PR00153; CSAPPISMRASE.
DR SUPFAM; SSF50891; Cyclophilin-like; 1.
DR PROSITE; PS50072; CSA_PPIASE_2; 1.
PE 3: Inferred from homology;
KW Isomerase {ECO:0000256|ARBA:ARBA00023235, ECO:0000256|RuleBase:RU363019};
KW Reference proteome {ECO:0000313|Proteomes:UP000241394};
KW Rotamase {ECO:0000256|ARBA:ARBA00023110, ECO:0000256|RuleBase:RU363019}.
FT DOMAIN 107..256
FT /note="PPIase cyclophilin-type"
FT /evidence="ECO:0000259|PROSITE:PS50072"
FT REGION 43..64
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 260 AA; 27978 MW; 83687EF667C57984 CRC64;
MAVPCATVSN VGSLSFRRSI SQIYFLGPSS TSSVNVEKSL LPSSTSLSSS SKGLFSRSSS
SLSPLKSSFR RKRCIFSSVG ASAEVAKPQS KVTNKVYLDI SIGDPPEPVG RIVIGLYGDV
VPYAAENFRA LCTGESGFGY KGSPFHRVMK DSFIQGGDWY TKDGYSSRSV YGQPFEDENF
TLSHIGPGVV SMANGGPHSN GSQFFICTNE IPDLDGKHVV FGQVLEGMDI VKLIESQETD
ENECPQTWVV ISNCGELPLN
//
