ID   A0A2R6PG12_9APHY        Unreviewed;       673 AA.
AC   A0A2R6PG12;
DT   20-JUN-2018, integrated into UniProtKB/TrEMBL.
DT   20-JUN-2018, sequence version 1.
DT   24-JAN-2024, entry version 19.
DE   RecName: Full=VLRF1 domain-containing protein {ECO:0000259|Pfam:PF18826};
GN   ORFNames=PHLCEN_2v4865 {ECO:0000313|EMBL:PSR90572.1};
OS   Hermanssonia centrifuga.
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC   Polyporales; Meruliaceae; Hermanssonia.
OX   NCBI_TaxID=98765 {ECO:0000313|EMBL:PSR90572.1, ECO:0000313|Proteomes:UP000186601};
RN   [1] {ECO:0000313|EMBL:PSR90572.1, ECO:0000313|Proteomes:UP000186601}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=FBCC195 {ECO:0000313|EMBL:PSR90572.1,
RC   ECO:0000313|Proteomes:UP000186601};
RA   Granchi Z., Peng M., de Vries R.P., Hilden K., Makela M.R., Grigoriev I.,
RA   Riley R.;
RT   "Genome sequence of the basidiomycete white-rot fungus Phlebia
RT   centrifuga.";
RL   Submitted (FEB-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC   -!- SIMILARITY: Belongs to the ANKZF1/VMS1 family.
CC       {ECO:0000256|ARBA:ARBA00009262}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PSR90572.1}.
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DR   EMBL; MLYV02000494; PSR90572.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2R6PG12; -.
DR   STRING; 98765.A0A2R6PG12; -.
DR   Proteomes; UP000186601; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.
DR   Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 1.
DR   InterPro; IPR002110; Ankyrin_rpt.
DR   InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR   InterPro; IPR047139; ANKZ1/VMS1.
DR   InterPro; IPR041175; VLRF1/Vms1.
DR   PANTHER; PTHR16036; ANKYRIN REPEAT AND ZINC FINGER DOMAIN-CONTAINING PROTEIN 1; 1.
DR   PANTHER; PTHR16036:SF2; ANKYRIN REPEAT AND ZINC FINGER DOMAIN-CONTAINING PROTEIN 1; 1.
DR   Pfam; PF00023; Ank; 1.
DR   Pfam; PF18826; bVLRF1; 1.
DR   PROSITE; PS50297; ANK_REP_REGION; 1.
DR   PROSITE; PS50088; ANK_REPEAT; 1.
PE   3: Inferred from homology;
KW   ANK repeat {ECO:0000256|ARBA:ARBA00023043, ECO:0000256|PROSITE-
KW   ProRule:PRU00023}; Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Endonuclease {ECO:0000256|ARBA:ARBA00022759};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Nuclease {ECO:0000256|ARBA:ARBA00022722};
KW   Reference proteome {ECO:0000313|Proteomes:UP000186601};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT   DOMAIN          199..365
FT                   /note="VLRF1"
FT                   /evidence="ECO:0000259|Pfam:PF18826"
FT   REPEAT          464..486
FT                   /note="ANK"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT   REGION          125..149
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          215..243
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          496..516
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          574..650
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        574..607
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        614..628
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   673 AA;  75043 MW;  E35FAA73AEF28A3D CRC64;
     MAPQEHYHAF SLPSQLLRTL IPRTALNQPA PPSRSPSPAP AAATNSARAC NICLAAVFAD
     VNEQRTHYRS DWHRYNVKIR LNGGSPVGEA QFAQLVDGLE DSISGSESSS DSDVDSDDAV
     SALVHKTKRL HRPTKSDDES PSSTGPNTPL IWFHSPPSTQ LGIYKVLYPT YVLSQHSPQE
     YLEALKAMQS RIEGEGRTWA LFMVAGGHFA GAVVRVQRPE DDEETEDGKA GKKGKQKKTK
     PDTEVLKHKT FHRYTTRRKQ GGSQGANDNA KTKAVSAGAM LRRYGEQALR DDIRNLIADW
     ADEIDGCERI FIRASVSNRK IFVDYENAII HKGDDRLRTF PFPTRRPTQS ELNRCLLELT
     RVKTSYLTED ALRAQDEAYI ASLPKPKPIP VQSSPSPALP QAPKLSPEEL ARKEVERVVR
     EKWTRVLEMV GKGRLDTIKT FWARESESLG GVDVRIPEGV DDADGKTILM VAVRMGQEDI
     VQWLLEEAHA DPTIDVLQRD SDPPTIDGVQ DDEDEDDLAK PVLGGTRRTA YDLARSREVR
     NVFRRCAADH PDWWDWLGVE NGGARVPSIL SKEMEEGREE KKKVRRKGLK DRVKEREAKE
     KERAPSPSFV VEEPSKVEKV RIKETVEGPR KLGGSAGASE GVAGLTPEMR AKVERERRAR
     AAEARMKALG GTR
//