ID   A0A2R6PJ80_9APHY        Unreviewed;      1315 AA.
AC   A0A2R6PJ80;
DT   20-JUN-2018, integrated into UniProtKB/TrEMBL.
DT   20-JUN-2018, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   RecName: Full=Ras-GAP domain-containing protein {ECO:0000259|PROSITE:PS50018};
GN   ORFNames=PHLCEN_2v4733 {ECO:0000313|EMBL:PSR92203.1};
OS   Hermanssonia centrifuga.
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC   Polyporales; Meruliaceae; Hermanssonia.
OX   NCBI_TaxID=98765 {ECO:0000313|EMBL:PSR92203.1, ECO:0000313|Proteomes:UP000186601};
RN   [1] {ECO:0000313|EMBL:PSR92203.1, ECO:0000313|Proteomes:UP000186601}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=FBCC195 {ECO:0000313|EMBL:PSR92203.1,
RC   ECO:0000313|Proteomes:UP000186601};
RA   Granchi Z., Peng M., de Vries R.P., Hilden K., Makela M.R., Grigoriev I.,
RA   Riley R.;
RT   "Genome sequence of the basidiomycete white-rot fungus Phlebia
RT   centrifuga.";
RL   Submitted (FEB-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PSR92203.1}.
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DR   EMBL; MLYV02000479; PSR92203.1; -; Genomic_DNA.
DR   STRING; 98765.A0A2R6PJ80; -.
DR   Proteomes; UP000186601; Unassembled WGS sequence.
DR   GO; GO:0005096; F:GTPase activator activity; IEA:UniProt.
DR   Gene3D; 3.40.525.10; CRAL-TRIO lipid binding domain; 1.
DR   Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR001251; CRAL-TRIO_dom.
DR   InterPro; IPR036865; CRAL-TRIO_dom_sf.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   InterPro; IPR039360; Ras_GTPase.
DR   InterPro; IPR023152; RasGAP_CS.
DR   InterPro; IPR001936; RasGAP_dom.
DR   InterPro; IPR008936; Rho_GTPase_activation_prot.
DR   PANTHER; PTHR10194:SF142; NEUROFIBROMIN; 1.
DR   PANTHER; PTHR10194; RAS GTPASE-ACTIVATING PROTEINS; 1.
DR   Pfam; PF13716; CRAL_TRIO_2; 1.
DR   Pfam; PF00616; RasGAP; 1.
DR   SMART; SM00323; RasGAP; 1.
DR   SUPFAM; SSF48371; ARM repeat; 1.
DR   SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR   PROSITE; PS00509; RAS_GTPASE_ACTIV_1; 1.
DR   PROSITE; PS50018; RAS_GTPASE_ACTIV_2; 1.
PE   4: Predicted;
KW   Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW   Reference proteome {ECO:0000313|Proteomes:UP000186601}.
FT   DOMAIN          1..119
FT                   /note="Ras-GAP"
FT                   /evidence="ECO:0000259|PROSITE:PS50018"
SQ   SEQUENCE   1315 AA;  145586 MW;  7E75EE7DDF7EE0EC CRC64;
     MTSLPPGHGY DLDPAKAPNQ DFLQNQKDLE FVASSFLEII AASVPAFPSM FREICAHIGQ
     AVNKVWPEAK FSALGAFIFL RFISPAIVNP ALVDVDAPSD PIMRRGLMNI AKIVQNLANN
     IFFGKEAHML PLNDFLSANI VNVTRFLSEI NKYTPPQEEE QDEWLDTAYD DTDTIVLHRF
     FDKHADKVGK ELLSAASKAS ETETDEEKAT GTGKRSWNAI CNALVETTQV SLIPNMSPFT
     SSEHPEYLDL MSRFSHRDTS PVHHLFVPAV TPQDQPAVFV LSLAKVQVEI LDLELLLFYI
     FKTISAPLYE KRNFEVIFDW TGFPPSAQIP MHWLKFVYEI LPSNIRARFR TSRTLIPNAM
     ALRYMRRLYN LTNGASMASS HTLHTSLVEL LRCYSGDISL PSLSYVAEQE SEPGDDFDEI
     FMRNNHSMRV PVILRVAQSH LRITTMKATA ISNSMSCRAT EIIPLADISD IYNVATGHDA
     NEFIIRKIRH GTTLYFTSST RDSVVKAIRS AKGSMRNVQI PVFERFSRLS NVIATLLHIG
     MVNIGSDNEE LRVASYDLLC SVCTYLDFEG KPVVPTKSIF VPGRAGPFVI QLSEKLASFS
     PQLTLDFIAE VAAGMEKTSV SQRIACLQYL SPWIKNLSHF TNPTDHLYEQ SGAKFRDCVR
     ILIDLTLADQ EIHAVVQKCI WTEVGKLDSE SVNTILDELM RAAVDGGIGS QRCELVADTM
     ASLTSINVRG RIGSRLRKVM GKTSSKPSKS LPENVHWNEI ACLTRLCLVA NYLPKNAAHV
     HLFIAEGAHY VSLVAGTGQI LVRTSVYGLV VNVLHSIYIS KSTSDSVSPE IQALLEDCAS
     PEVLKLFGLA RPTSTSDYVA YDPPNDKQQL DSLEKLGNLL VRMMNCISPS QALLNVWRAR
     WMSLVTSSAF QTCPAIQTRA FITLGILATS DVDDDLLYQM LVAFKTALED YDDSDTTAVV
     SMLRCICKVA PSLPPKSRYL PQLFWLAVAL IQSSNVAVYI EAIQLMRATL DTMAQQGAFK
     ERGVAPTLLD GRQHLEEFAC QIDQILGLSF DSSFSFSLSA VIFKGVRHQN LKEYAEGALR
     SLLRVTVQSC SDHSHTEDSA GSPICADLLG FFIALLPLST TSGAFRKLLQ EANMDVSWMS
     EEIIPVEDDD LISRVPFALL GITDGASALY VTSFISAILT TAQGDDTETE ILFTILSDIA
     NGYPEVISTT FESLQDQIKD TFATASNPNT LSAVSNVFRV AMQDSRRTIN VRGSTSTLST
     VEEANGYGLV RSHYNALDEL GMQGLTNGYQ FMAAGRPQSI TITQWIAQLV MKIIE
//