ID A0A2R6QJB5_ACTCC Unreviewed; 375 AA.
AC A0A2R6QJB5;
DT 20-JUN-2018, integrated into UniProtKB/TrEMBL.
DT 20-JUN-2018, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE RecName: Full=protein-serine/threonine phosphatase {ECO:0000256|ARBA:ARBA00013081};
DE EC=3.1.3.16 {ECO:0000256|ARBA:ARBA00013081};
GN ORFNames=CEY00_Acc16522 {ECO:0000313|EMBL:PSS09499.1};
OS Actinidia chinensis var. chinensis (Chinese soft-hair kiwi).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; Ericales; Actinidiaceae; Actinidia.
OX NCBI_TaxID=1590841 {ECO:0000313|EMBL:PSS09499.1, ECO:0000313|Proteomes:UP000241394};
RN [1] {ECO:0000313|EMBL:PSS09499.1, ECO:0000313|Proteomes:UP000241394}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Red5 {ECO:0000313|Proteomes:UP000241394};
RC TISSUE=Young leaf {ECO:0000313|EMBL:PSS09499.1};
RA Pilkington S., Crowhurst R., Hilario E., Nardozza S., Fraser L., Peng Y.,
RA Gunaseelan K., Simpson R., Tahir J., Deroles S., Templeton K., Luo Z.,
RA Davy M., Cheng C., Mcneilage M., Scaglione D., Liu Y., Zhang Q., Datson P.,
RA De Silva N., Gardiner S., Bassett H., Chagne D., Mccallum J., Dzierzon H.,
RA Deng C., Wang Y.-Y., Barron N., Manako K., Bowen J., Foster T., Erridge Z.,
RA Tiffin H., Waite C., Davies K., Grierson E., Laing W., Kirk R., Chen X.,
RA Wood M., Montefiori M., Brummell D., Schwinn K., Catanach A., Fullerton C.,
RA Li D., Meiyalaghan S., Nieuwenhuizen N., Read N., Prakash R., Hunter D.,
RA Zhang H., Mckenzie M., Knabel M., Harris A., Allan A., Chen A., Janssen B.,
RA Plunkett B., Dwamena C., Voogd C., Leif D., Lafferty D., Souleyre E.,
RA Varkonyi-Gasic E., Gambi F., Hanley J., Yao J.-L., Cheung J., David K.,
RA Warren B., Marsh K., Snowden K., Lin-Wang K., Brian L.,
RA Martinez-Sanchez M., Wang M., Ileperuma N., Macnee N., Campin R.,
RA Mcatee P., Drummond R., Espley R., Ireland H., Wu R., Atkinson R.,
RA Karunairetnam S., Bulley S., Chunkath S., Hanley Z., Storey R.,
RA Thrimawithana A., Thomson S., David C., Testolin R.;
RT "An improved, manually edited Actinidia chinensis var. chinensis
RT (kiwifruit) genome highlights the challenges associated with draft genomes
RT and gene prediction in plants.";
RL Submitted (JUL-2017) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000241394}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Red5 {ECO:0000313|Proteomes:UP000241394};
RX PubMed=29661190; DOI=10.1186/s12864-018-4656-3;
RA Pilkington S.M., Crowhurst R., Hilario E., Nardozza S., Fraser L., Peng Y.,
RA Gunaseelan K., Simpson R., Tahir J., Deroles S.C., Templeton K., Luo Z.,
RA Davy M., Cheng C., McNeilage M., Scaglione D., Liu Y., Zhang Q., Datson P.,
RA De Silva N., Gardiner S.E., Bassett H., Chagne D., McCallum J.,
RA Dzierzon H., Deng C., Wang Y.Y., Barron L., Manako K., Bowen J.,
RA Foster T.M., Erridge Z.A., Tiffin H., Waite C.N., Davies K.M.,
RA Grierson E.P., Laing W.A., Kirk R., Chen X., Wood M., Montefiori M.,
RA Brummell D.A., Schwinn K.E., Catanach A., Fullerton C., Li D.,
RA Meiyalaghan S., Nieuwenhuizen N., Read N., Prakash R., Hunter D., Zhang H.,
RA McKenzie M., Knabel M., Harris A., Allan A.C., Gleave A., Chen A.,
RA Janssen B.J., Plunkett B., Ampomah-Dwamena C., Voogd C., Leif D.,
RA Lafferty D., Souleyre E.J.F., Varkonyi-Gasic E., Gambi F., Hanley J.,
RA Yao J.L., Cheung J., David K.M., Warren B., Marsh K., Snowden K.C.,
RA Lin-Wang K., Brian L., Martinez-Sanchez M., Wang M., Ileperuma N.,
RA Macnee N., Campin R., McAtee P., Drummond R.S.M., Espley R.V.,
RA Ireland H.S., Wu R., Atkinson R.G., Karunairetnam S., Bulley S.,
RA Chunkath S., Hanley Z., Storey R., Thrimawithana A.H., Thomson S.,
RA David C., Testolin R., Huang H., Hellens R.P., Schaffer R.J.;
RT "A manually annotated Actinidia chinensis var. chinensis (kiwifruit) genome
RT highlights the challenges associated with draft genomes and gene prediction
RT in plants.";
RL BMC Genomics 19:257-257(2018).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=H2O + O-phospho-L-seryl-[protein] = L-seryl-[protein] +
CC phosphate; Xref=Rhea:RHEA:20629, Rhea:RHEA-COMP:9863, Rhea:RHEA-
CC COMP:11604, ChEBI:CHEBI:15377, ChEBI:CHEBI:29999, ChEBI:CHEBI:43474,
CC ChEBI:CHEBI:83421; EC=3.1.3.16;
CC Evidence={ECO:0000256|ARBA:ARBA00001512};
CC -!- CATALYTIC ACTIVITY:
CC Reaction=H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] +
CC phosphate; Xref=Rhea:RHEA:47004, Rhea:RHEA-COMP:11060, Rhea:RHEA-
CC COMP:11605, ChEBI:CHEBI:15377, ChEBI:CHEBI:30013, ChEBI:CHEBI:43474,
CC ChEBI:CHEBI:61977; EC=3.1.3.16;
CC Evidence={ECO:0000256|ARBA:ARBA00001482};
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
CC -!- COFACTOR:
CC Name=Mn(2+); Xref=ChEBI:CHEBI:29035;
CC Evidence={ECO:0000256|ARBA:ARBA00001936};
CC -!- SIMILARITY: Belongs to the PP2C family. {ECO:0000256|ARBA:ARBA00006702,
CC ECO:0000256|RuleBase:RU003465}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PSS09499.1}.
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DR EMBL; NKQK01000015; PSS09499.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2R6QJB5; -.
DR STRING; 1590841.A0A2R6QJB5; -.
DR EnsemblPlants; PSS09499; PSS09499; CEY00_Acc16522.
DR Gramene; PSS09499; PSS09499; CEY00_Acc16522.
DR InParanoid; A0A2R6QJB5; -.
DR OMA; HEFLIMA; -.
DR Proteomes; UP000241394; Chromosome lg15.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0017018; F:myosin phosphatase activity; IEA:UniProtKB-EC.
DR CDD; cd00143; PP2Cc; 1.
DR Gene3D; 3.60.40.10; PPM-type phosphatase domain; 1.
DR InterPro; IPR015655; PP2C.
DR InterPro; IPR000222; PP2C_BS.
DR InterPro; IPR036457; PPM-type-like_dom_sf.
DR InterPro; IPR001932; PPM-type_phosphatase-like_dom.
DR PANTHER; PTHR47992; PROTEIN PHOSPHATASE; 1.
DR PANTHER; PTHR47992:SF86; PROTEIN-SERINE_THREONINE PHOSPHATASE; 1.
DR Pfam; PF00481; PP2C; 1.
DR SMART; SM00331; PP2C_SIG; 1.
DR SMART; SM00332; PP2Cc; 1.
DR SUPFAM; SSF81606; PP2C-like; 1.
DR PROSITE; PS01032; PPM_1; 1.
DR PROSITE; PS51746; PPM_2; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU003465};
KW Manganese {ECO:0000256|ARBA:ARBA00023211};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Protein phosphatase {ECO:0000256|ARBA:ARBA00022912,
KW ECO:0000256|RuleBase:RU003465};
KW Reference proteome {ECO:0000313|Proteomes:UP000241394}.
FT DOMAIN 120..371
FT /note="PPM-type phosphatase"
FT /evidence="ECO:0000259|PROSITE:PS51746"
SQ SEQUENCE 375 AA; 40412 MW; 2622C4634AF31F20 CRC64;
MSCTIAISNS PVFSPSRISS SLFYKSSLSS SPDKALNINH SPSSSSSTPS LPLRLLRLQK
PPSGLNRESG DVVVSNSSSP TLLKRKRPAR LDIPISCVGF AGPATPAVDG TQVTEVDGDG
YSVCCKRGRR EAMEDRYSAV VNLQGDPKQA FFGIFDGHGG AKAAEFAAEN LNKNILNEVG
RRGGQELEEA VKFGYLNTDS EFLKEDIHGG SCCVTALIRK GQLVVSNAGD CRAVMSRGGV
AEALTSDHRP SRDDEKDRIE NLGGFVDCCH GVWRIQGSLA VSRGIGDGHL KQWVTAEPET
KILRIEPVYE FLILASDGLW EKVTNQEAVD IARPLCVGIQ KPELLSACRK LAALSVSRGS
KDDISVMLIQ LGRFY
//
