ID   A0A2R6S477_9APHY        Unreviewed;       568 AA.
AC   A0A2R6S477;
DT   20-JUN-2018, integrated into UniProtKB/TrEMBL.
DT   20-JUN-2018, sequence version 1.
DT   24-JAN-2024, entry version 11.
DE   RecName: Full=RING-type E3 ubiquitin transferase {ECO:0000256|ARBA:ARBA00012483};
DE            EC=2.3.2.27 {ECO:0000256|ARBA:ARBA00012483};
GN   ORFNames=PHLCEN_2v1094 {ECO:0000313|EMBL:PSS37055.1};
OS   Hermanssonia centrifuga.
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC   Polyporales; Meruliaceae; Hermanssonia.
OX   NCBI_TaxID=98765 {ECO:0000313|EMBL:PSS37055.1, ECO:0000313|Proteomes:UP000186601};
RN   [1] {ECO:0000313|EMBL:PSS37055.1, ECO:0000313|Proteomes:UP000186601}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=FBCC195 {ECO:0000313|EMBL:PSS37055.1,
RC   ECO:0000313|Proteomes:UP000186601};
RA   Granchi Z., Peng M., de Vries R.P., Hilden K., Makela M.R., Grigoriev I.,
RA   Riley R.;
RT   "Genome sequence of the basidiomycete white-rot fungus Phlebia
RT   centrifuga.";
RL   Submitted (FEB-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine +
CC         [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-
CC         cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.;
CC         EC=2.3.2.27; Evidence={ECO:0000256|ARBA:ARBA00000900};
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PSS37055.1}.
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DR   EMBL; MLYV02000084; PSS37055.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2R6S477; -.
DR   STRING; 98765.A0A2R6S477; -.
DR   Proteomes; UP000186601; Unassembled WGS sequence.
DR   GO; GO:0004842; F:ubiquitin-protein transferase activity; IEA:InterPro.
DR   CDD; cd12885; SPRY_RanBP_like; 1.
DR   Gene3D; 2.60.120.920; -; 1.
DR   InterPro; IPR001870; B30.2/SPRY.
DR   InterPro; IPR043136; B30.2/SPRY_sf.
DR   InterPro; IPR013320; ConA-like_dom_sf.
DR   InterPro; IPR045129; RNF123/RSPRY1-like.
DR   InterPro; IPR003877; SPRY_dom.
DR   InterPro; IPR044736; Vid30/RanBPM/SPLA_SPRY.
DR   PANTHER; PTHR13363:SF5; E3 UBIQUITIN-PROTEIN LIGASE RNF123; 1.
DR   PANTHER; PTHR13363; RING FINGER AND SRY DOMAIN-CONTAINING; 1.
DR   Pfam; PF00622; SPRY; 1.
DR   SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR   PROSITE; PS50188; B302_SPRY; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000186601}.
FT   DOMAIN          1..107
FT                   /note="B30.2/SPRY"
FT                   /evidence="ECO:0000259|PROSITE:PS50188"
SQ   SEQUENCE   568 AA;  64806 MW;  CD27BA776D22FACE CRC64;
     MAGSRSDLTH AVGAIHDSWG YNSDGIASHG NPMPDQYAPK FHAGDIIGCG TMYDLCGGSI
     FYTLNGSFLG IFFKDATERC ESDEFFPSVS LCHPLDTVRA NFGQQPFRYP IARIIRDSSR
     ETQWPRPPKP PSFSSEIIYI ILGGLAPNND MDKTHMVSCS LVCRYWSRIL SPYLFRTIKL
     QSKDEMDVMS AQVDNSNRQM SAAIISLTVH ERAHDVWAYK VAMSLANRCH NLKTLTQERD
     PLDRLGWEII RQCTPPGISR SLPALYSAYR AVTTFVLINQ HFSSFAALTQ LVSAFPVLKT
     LKCERITWDK RPDNPRLLRA PRCLSTIQVE CCDTDWRMAR LFIARWGRLP LDWDPSSKSP
     ELHRNDSLFV HGLLNTEDTQ PFDTSELLFA SSTDNHAWHL KMTLMDRSRT EAMKWDFIFC
     PRAIQDHIIK TCLTELRICM LNSFDPDEVG PRIPLLDKLF SEAPLAFLAN VTIVSSEYMS
     PEIAAVKTSK LRRHLSHLQA AGKLRLCLSG QTTAGHEEQG EQEITEEVEQ FVTERMRIEE
     NERAEMICME ESQWAERISR WQWGEPEL
//