ID   A0A2R6S5N5_9APHY        Unreviewed;       963 AA.
AC   A0A2R6S5N5;
DT   20-JUN-2018, integrated into UniProtKB/TrEMBL.
DT   20-JUN-2018, sequence version 1.
DT   24-JAN-2024, entry version 11.
DE   RecName: Full=DH domain-containing protein {ECO:0000259|PROSITE:PS50010};
GN   ORFNames=PHLCEN_2v581 {ECO:0000313|EMBL:PSS37565.1};
OS   Hermanssonia centrifuga.
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC   Polyporales; Meruliaceae; Hermanssonia.
OX   NCBI_TaxID=98765 {ECO:0000313|EMBL:PSS37565.1, ECO:0000313|Proteomes:UP000186601};
RN   [1] {ECO:0000313|EMBL:PSS37565.1, ECO:0000313|Proteomes:UP000186601}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=FBCC195 {ECO:0000313|EMBL:PSS37565.1,
RC   ECO:0000313|Proteomes:UP000186601};
RA   Granchi Z., Peng M., de Vries R.P., Hilden K., Makela M.R., Grigoriev I.,
RA   Riley R.;
RT   "Genome sequence of the basidiomycete white-rot fungus Phlebia
RT   centrifuga.";
RL   Submitted (FEB-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PSS37565.1}.
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DR   EMBL; MLYV02000035; PSS37565.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2R6S5N5; -.
DR   STRING; 98765.A0A2R6S5N5; -.
DR   Proteomes; UP000186601; Unassembled WGS sequence.
DR   GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR   Gene3D; 1.20.900.10; Dbl homology (DH) domain; 1.
DR   InterPro; IPR035899; DBL_dom_sf.
DR   InterPro; IPR000219; DH-domain.
DR   PANTHER; PTHR45924; FI17866P1; 1.
DR   PANTHER; PTHR45924:SF2; FI17866P1; 1.
DR   Pfam; PF00621; RhoGEF; 1.
DR   SMART; SM00325; RhoGEF; 1.
DR   SUPFAM; SSF48065; DBL homology domain (DH-domain); 1.
DR   PROSITE; PS50010; DH_2; 1.
PE   4: Predicted;
KW   Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW   Reference proteome {ECO:0000313|Proteomes:UP000186601}.
FT   DOMAIN          98..293
FT                   /note="DH"
FT                   /evidence="ECO:0000259|PROSITE:PS50010"
FT   REGION          1..99
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          319..365
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          526..547
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          562..637
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          656..802
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          823..851
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        562..591
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        608..622
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        661..678
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        705..719
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        734..768
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        771..785
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   963 AA;  104624 MW;  89273A072BD7B0AD CRC64;
     MDAKPLPPPA RDDRLPPLPP SHYDNSATSW DVSPPPPPKH TLDREYDASQ YNTRGHNLPD
     IHSSALSPHD GFDVPPITPI SPVGSTPSSP SGDAKSKKKA NPLTDLIETE KVYVDLLTGI
     IRKVAAAWSR SNLPPPELDT MFRSVESVYK ANRSLLSKLK EIGANPSSPK ALGDLLMRWI
     DDLEAPYTKY ATNYCAGFDE WDPVQSNTRL RTTLAIFSSS NPPPLPSSSP EHPPEPPLWT
     LDDLFLLPKG RLGYYRKLYS RLLKSTVPGR SDHRLLSGAL DKLDNLLVTL DERAILKVGA
     NTQAPQDTED EVVFDMRTRQ STVPLNSQTQ RESDSTHGSG SIANDDRLSQ ETPPTSVERT
     STAAMSIPIT DLERRLSTEQ TLDIFTMQPK QVRLQIAPPT LHYTRDLRIC ADVVMTFTPR
     STGVDVTHER GRIFVLTDLL LMCERMTPRE AARFTPEGPD MWLLYPPLAG KHLRVVPVDG
     SDNAFTVTIL RKEIVTMYAE SRQLRDRIVA EFRECIDAAA TLVPAKNQAP PPPVPKLPSG
     GGGLPTSPTA LRGPSDMFSE YPNMSSILPN HPSSPSNSLP RMQSPPVNGF ANMNISEDPH
     ARDMSRMPSL SNAMSGSAYP PRSASMASPD GPGPYHSPIE NMSGQGFGPG QMMRQGSFGP
     GQVMPSMNPG QTMPHQQFVP GQIMPPPRGA SYGAGAPDPS VAGPRRSGST YSENLPSSPY
     GPPGSMRGMS PYAPSMSRPS SDGSGGPALR KSTSSRSLAS QYDSRQSNGP LPPMPAYPDG
     LIPPSRPFLP RSDSSSSLSS LPSLYAPQAR PLLPSAQYSV RSMSTGPSFI DPSPPSSPVE
     ETPKPTGPVT SRVSEQMKCK VFLQEHHAKW KSLGSAKLKL YHESPTNVKQ LVVQADSKQN
     VLISTIVLED GVERVGKTGV AIELSDKGQR MGVVYMLQLR DERSAGSLFE SLLAGSDRSE
     VRT
//