ID A0A2R7KLF7_9SPHI Unreviewed; 595 AA.
AC A0A2R7KLF7;
DT 20-JUN-2018, integrated into UniProtKB/TrEMBL.
DT 20-JUN-2018, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE SubName: Full=Chloride channel protein {ECO:0000313|EMBL:PTS98256.1};
GN ORFNames=DBR11_15430 {ECO:0000313|EMBL:PTS98256.1};
OS Pedobacter sp. HMWF019.
OC Bacteria; Bacteroidota; Sphingobacteriia; Sphingobacteriales;
OC Sphingobacteriaceae; Pedobacter.
OX NCBI_TaxID=2056856 {ECO:0000313|EMBL:PTS98256.1, ECO:0000313|Proteomes:UP000244301};
RN [1] {ECO:0000313|EMBL:PTS98256.1, ECO:0000313|Proteomes:UP000244301}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HMWF019 {ECO:0000313|EMBL:PTS98256.1,
RC ECO:0000313|Proteomes:UP000244301};
RA Go L.Y., Mitchell J.A.;
RL Submitted (APR-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PTS98256.1}.
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DR EMBL; QAIL01000264; PTS98256.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2R7KLF7; -.
DR OrthoDB; 9812438at2; -.
DR Proteomes; UP000244301; Unassembled WGS sequence.
DR GO; GO:0034707; C:chloride channel complex; IEA:UniProtKB-KW.
DR GO; GO:0005247; F:voltage-gated chloride channel activity; IEA:InterPro.
DR CDD; cd02205; CBS_pair_SF; 1.
DR CDD; cd00400; Voltage_gated_ClC; 1.
DR Gene3D; 3.10.580.10; CBS-domain; 1.
DR Gene3D; 1.10.3080.10; Clc chloride channel; 1.
DR InterPro; IPR000644; CBS_dom.
DR InterPro; IPR046342; CBS_dom_sf.
DR InterPro; IPR014743; Cl-channel_core.
DR InterPro; IPR001807; Cl-channel_volt-gated.
DR PANTHER; PTHR43427; CHLORIDE CHANNEL PROTEIN CLC-E; 1.
DR PANTHER; PTHR43427:SF6; CHLORIDE CHANNEL PROTEIN CLC-E; 1.
DR Pfam; PF00571; CBS; 1.
DR Pfam; PF00654; Voltage_CLC; 1.
DR PRINTS; PR00762; CLCHANNEL.
DR SUPFAM; SSF54631; CBS-domain pair; 1.
DR SUPFAM; SSF81340; Clc chloride channel; 1.
DR PROSITE; PS51371; CBS; 2.
PE 4: Predicted;
KW CBS domain {ECO:0000256|PROSITE-ProRule:PRU00703};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000244301};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 25..45
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 65..83
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 161..187
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 199..217
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 229..252
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 272..290
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 320..345
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 351..371
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 383..406
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 412..429
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 469..525
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
FT DOMAIN 533..593
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
SQ SEQUENCE 595 AA; 65317 MW; 7FBB992E81FF7051 CRC64;
MYVRLVNYID ALNQYRRTKI SNRNFLVIAA LIVGILAGLA AAALKSITHH IEDFLQSGFH
WHYKYYLYIF FPLIGILLSV MYVRRFIRKG KFETGLTPLL FTISKKSSKV EPHNIYSQII
TAALTVGFGG STGLEAPIVT SGAGIGSVIG RFLGLSYRET TMLLACGAAA GIAGAFNSPI
AGIVFAIEIL LPEFTIPAFI PLLLASATAA VVSRLFYTEQ LFYLVTEGWV MQALPFYVLL
AVCIGFFSIY FVKVNYLVKS YFYKLQHPYK KVVIGGLMLG ALVFLFPTLY GEGYVTIKNL
LSGNYTAVIS NSIFSEYATL PVAIILFTLI TVFAKSFGTL ITLGAGGNGG IFAPSLIMGG
LIGFLVAFTA NTLGIAHLNV ANFIVAGMAA SLSAIMHAPL TGIFLIAEIT GGYILMVPLM
ITSAISYFIS RSANKYSIYT KPLAESGALL SHEDKDTTVL NMMKLKYLIE KDYLVLKQSD
LLSEKMGEIL QAKRNLFPVV DADEIFIGLI YMEDILKITI KPGEEELSVS ELMHPAPEIV
VSNDALKTVL TKMETQNAWL LPVVDEQGRY VGFVSKTSIF NKYRALLSRQ ADYME
//
