ID   A0A2R7KRS0_9SPHI        Unreviewed;       427 AA.
AC   A0A2R7KRS0;
DT   20-JUN-2018, integrated into UniProtKB/TrEMBL.
DT   20-JUN-2018, sequence version 1.
DT   27-MAR-2024, entry version 17.
DE   RecName: Full=Insulinase family protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=DBR11_10765 {ECO:0000313|EMBL:PTT00104.1};
OS   Pedobacter sp. HMWF019.
OC   Bacteria; Bacteroidota; Sphingobacteriia; Sphingobacteriales;
OC   Sphingobacteriaceae; Pedobacter.
OX   NCBI_TaxID=2056856 {ECO:0000313|EMBL:PTT00104.1, ECO:0000313|Proteomes:UP000244301};
RN   [1] {ECO:0000313|EMBL:PTT00104.1, ECO:0000313|Proteomes:UP000244301}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=HMWF019 {ECO:0000313|EMBL:PTT00104.1,
RC   ECO:0000313|Proteomes:UP000244301};
RA   Go L.Y., Mitchell J.A.;
RL   Submitted (APR-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PTT00104.1}.
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DR   EMBL; QAIL01000166; PTT00104.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2R7KRS0; -.
DR   OrthoDB; 9811314at2; -.
DR   Proteomes; UP000244301; Unassembled WGS sequence.
DR   GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR   Gene3D; 3.30.830.10; Metalloenzyme, LuxS/M16 peptidase-like; 2.
DR   InterPro; IPR011249; Metalloenz_LuxS/M16.
DR   InterPro; IPR011765; Pept_M16_N.
DR   InterPro; IPR007863; Peptidase_M16_C.
DR   PANTHER; PTHR11851:SF149; GH01077P; 1.
DR   PANTHER; PTHR11851; METALLOPROTEASE; 1.
DR   Pfam; PF00675; Peptidase_M16; 1.
DR   Pfam; PF05193; Peptidase_M16_C; 1.
DR   SUPFAM; SSF63411; LuxS/MPP-like metallohydrolase; 2.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000244301};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..21
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           22..427
FT                   /note="Insulinase family protein"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5015346752"
FT   DOMAIN          35..173
FT                   /note="Peptidase M16 N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00675"
FT   DOMAIN          195..353
FT                   /note="Peptidase M16 C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF05193"
SQ   SEQUENCE   427 AA;  48270 MW;  62C43396C88323A8 CRC64;
     MKRFILAPIF LVFLLPLKAQ HKAIDFTVNG LKVILRPTEK ETVSIRMFYR GGVMNYAPEQ
     AGIENMALTT AATGGSKNYS AADYKELNDE FGIEIQGSSG TDYGTITLDC ISKYLDKGWN
     FFADAVVNPA FEQPEFQSSK EKTIARIHSQ NADPESRIEK LSMSAIFQDS PYSTDPTGTE
     EIVTNFRIKQ VKDYYYQTLL NKNRMFLVVA GKITKEELEK KILASLSSIP EAPYTLPVYD
     QKLMEGEKLL TEQRDLATNY MSCVMNAPPM NNPDYLPFML SINALSSHLF YELRTKQSLS
     YSPGATIKSL QIPYMSMYVS TTQPVKAYQA IVNVYKSMRS NLFSQSLLDD IKKNHKRTYY
     RHQESSSAIV EDLGKAEIFG DYRIEENKIA SINKVSCQDM LNAVNKYLKG AIWIYLGDEP
     AGKAAFQ
//