ID A0A2R7QZ29_9MICC Unreviewed; 406 AA.
AC A0A2R7QZ29;
DT 20-JUN-2018, integrated into UniProtKB/TrEMBL.
DT 20-JUN-2018, sequence version 1.
DT 24-JAN-2024, entry version 16.
DE SubName: Full=Formaldehyde dehydrogenase, glutathione-independent {ECO:0000313|EMBL:PTT63886.1};
GN Name=fdhA {ECO:0000313|EMBL:PTT63886.1};
GN ORFNames=DBR22_15060 {ECO:0000313|EMBL:PTT63886.1};
OS Arthrobacter sp. HMWF013.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Micrococcaceae;
OC Arthrobacter.
OX NCBI_TaxID=2056849 {ECO:0000313|EMBL:PTT63886.1, ECO:0000313|Proteomes:UP000244718};
RN [1] {ECO:0000313|EMBL:PTT63886.1, ECO:0000313|Proteomes:UP000244718}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HMWF013 {ECO:0000313|EMBL:PTT63886.1,
RC ECO:0000313|Proteomes:UP000244718};
RA Go L.Y., Mitchell J.A.;
RL Submitted (APR-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947,
CC ECO:0000256|RuleBase:RU361277};
CC -!- SIMILARITY: Belongs to the zinc-containing alcohol dehydrogenase
CC family. {ECO:0000256|RuleBase:RU361277}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PTT63886.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; QAIQ01000406; PTT63886.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2R7QZ29; -.
DR OrthoDB; 241504at2; -.
DR Proteomes; UP000244718; Unassembled WGS sequence.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd08282; PFDH_like; 1.
DR Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR013149; ADH-like_C.
DR InterPro; IPR013154; ADH-like_N.
DR InterPro; IPR002328; ADH_Zn_CS.
DR InterPro; IPR011032; GroES-like_sf.
DR InterPro; IPR014184; HCHO_DH_non_GSH.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR NCBIfam; TIGR02819; fdhA_non_GSH; 1.
DR PANTHER; PTHR42813:SF3; GLUTATHIONE-INDEPENDENT FORMALDEHYDE DEHYDROGENASE; 1.
DR PANTHER; PTHR42813; ZINC-TYPE ALCOHOL DEHYDROGENASE-LIKE; 1.
DR Pfam; PF08240; ADH_N; 1.
DR Pfam; PF00107; ADH_zinc_N; 1.
DR SUPFAM; SSF50129; GroES-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS00059; ADH_ZINC; 1.
PE 3: Inferred from homology;
KW Metal-binding {ECO:0000256|RuleBase:RU361277};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000244718};
KW Zinc {ECO:0000256|RuleBase:RU361277}.
FT DOMAIN 43..153
FT /note="Alcohol dehydrogenase-like N-terminal"
FT /evidence="ECO:0000259|Pfam:PF08240"
FT DOMAIN 206..272
FT /note="Alcohol dehydrogenase-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF00107"
SQ SEQUENCE 406 AA; 42316 MW; 4F45A68E5448A79B CRC64;
MSGNRAVAYK GPGKVEVIDT EYPIFELKDG PGVNPANVGR KIPHGVILRT VTTNICGSDQ
HMVRGRTTAP AGLVLGHEIT GEVVETGPDV EFIKVGDIVS VPFNISCGRC RNCKERKTGI
CLNVNPDRPG SAYGYVDMGG WVGGQAEYVL VPYADWNMMK FPDRDQALEK IMDLTMLSDI
FPTGFHGAVT AGVGVGSTVY VAGAGPVGLA AAAGAQLLGA AVVIVGDLNE ERLGQARSFG
CETINVANGD PADQIEQILG VREVDAGVDA VGFEARGHGH GREAEEAPAT VLNSLMEITA
AGGALGIPGL YVTGDPGAVD DAAKKGSLSL SLGTGWAKSL AFTTGQCPVM KYNRQLMMAI
LHDRVQIAKA VNGKAITLDE APRGYAEFDA GAATKYVLNP NGYVSA
//
