ID A0A2R7YUR7_9ACTN Unreviewed; 717 AA.
AC A0A2R7YUR7;
DT 20-JUN-2018, integrated into UniProtKB/TrEMBL.
DT 20-JUN-2018, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=alpha-galactosidase {ECO:0000256|ARBA:ARBA00012755};
DE EC=3.2.1.22 {ECO:0000256|ARBA:ARBA00012755};
GN ORFNames=C7S10_16370 {ECO:0000313|EMBL:PUA80115.1};
OS Nocardioides currus.
OC Bacteria; Actinomycetota; Actinomycetes; Propionibacteriales;
OC Nocardioidaceae; Nocardioides.
OX NCBI_TaxID=2133958 {ECO:0000313|EMBL:PUA80115.1, ECO:0000313|Proteomes:UP000244867};
RN [1] {ECO:0000313|EMBL:PUA80115.1, ECO:0000313|Proteomes:UP000244867}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IB-3 {ECO:0000313|EMBL:PUA80115.1,
RC ECO:0000313|Proteomes:UP000244867};
RA Keele B.F.;
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Hydrolysis of terminal, non-reducing alpha-D-galactose
CC residues in alpha-D-galactosides, including galactose
CC oligosaccharides, galactomannans and galactolipids.; EC=3.2.1.22;
CC Evidence={ECO:0000256|ARBA:ARBA00001255};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PUA80115.1}.
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DR EMBL; PYXZ01000007; PUA80115.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2R7YUR7; -.
DR OrthoDB; 9758822at2; -.
DR Proteomes; UP000244867; Unassembled WGS sequence.
DR GO; GO:0004557; F:alpha-galactosidase activity; IEA:UniProtKB-EC.
DR GO; GO:0016052; P:carbohydrate catabolic process; IEA:InterPro.
DR CDD; cd14791; GH36; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR Gene3D; 2.70.98.60; alpha-galactosidase from lactobacil brevis; 1.
DR Gene3D; 2.60.40.1180; Golgi alpha-mannosidase II; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR038417; Alpga-gal_N_sf.
DR InterPro; IPR002252; Glyco_hydro_36.
DR InterPro; IPR031705; Glyco_hydro_36_C.
DR InterPro; IPR031704; Glyco_hydro_36_N.
DR InterPro; IPR013780; Glyco_hydro_b.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR PANTHER; PTHR43053:SF3; ALPHA-GALACTOSIDASE C-RELATED; 1.
DR PANTHER; PTHR43053; GLYCOSIDASE FAMILY 31; 1.
DR Pfam; PF16874; Glyco_hydro_36C; 1.
DR Pfam; PF16875; Glyco_hydro_36N; 1.
DR Pfam; PF02065; Melibiase; 1.
DR PRINTS; PR00743; GLHYDRLASE36.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
PE 4: Predicted;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000244867}.
FT DOMAIN 27..266
FT /note="Glycosyl hydrolase family 36 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF16875"
FT DOMAIN 624..711
FT /note="Glycosyl hydrolase family 36 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF16874"
SQ SEQUENCE 717 AA; 78282 MW; 7BF3AE83D4064359 CRC64;
MASPSPYTPV HLRRAGVSLL LAPDDAGRPV LLHWGADLGD LARDAVDGLL EARRPGVSRS
SYDAPRTTGL LPESALGFAG TPALEGHRTG GAATATTPRL ADWSVDVEDV PGADAAVRLD
AVDEEAGWAV SVDLVLSVAG LVRMRTSVTN TLDGHLHLGG VRNALPVGAH ACELLDLTGR
WCKERSPQRH PWVQGTHRRD GRHGRTGHDA TLLMVAGTPG FGFSAGEVWS VHTAWSGDHT
TYAERTAEGE CLLGGGELLA PGEVELARDE TYRSPWLLGS WSDAGLDPVS HRLHAHLRAG
SPRARGERPV VANTWEAVYF DHDLGRLSEL AEVAARVGVE RFVLDDGWFP ARRHDRAGLG
DWVVDREVWP DGLHPLVDRV GELGMQFGLW VEPEMVNEDS ELARTHPERV LRGRSELPPH
WRGQQVLDLQ DDDARTELRE ALLALLDEYD IAYLKWDHNR DLTDVTHDGR PAVHGQTLAA
YRLLDELRDA HPALEIESCS SGGARVDAEV LRHTDRIWPS DTIDPLERQH LQRWTSLLVP
PELIGSHVGG ATSHTTGRTH ALRYRAATAL LYSLGLECDL TRLDETEVAE LTSWIDLHKR
VRPLLSTGTL VHPDHADPAV LVTGVVAHDR SEAWFVVATV AATSTQHPAH LRLSGLDPDR
TYRLVEELAP AAGGADLTDR WRAGEGQLVT GRSLERAGVA LPVLWPEDAR VLHVVSA
//
