ID A0A2R7YZS6_9ACTN Unreviewed; 672 AA.
AC A0A2R7YZS6;
DT 20-JUN-2018, integrated into UniProtKB/TrEMBL.
DT 20-JUN-2018, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Fumarate reductase/succinate dehydrogenase flavoprotein subunit {ECO:0000313|EMBL:PUA81852.1};
GN ORFNames=C7S10_07280 {ECO:0000313|EMBL:PUA81852.1};
OS Nocardioides currus.
OC Bacteria; Actinomycetota; Actinomycetes; Propionibacteriales;
OC Nocardioidaceae; Nocardioides.
OX NCBI_TaxID=2133958 {ECO:0000313|EMBL:PUA81852.1, ECO:0000313|Proteomes:UP000244867};
RN [1] {ECO:0000313|EMBL:PUA81852.1, ECO:0000313|Proteomes:UP000244867}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IB-3 {ECO:0000313|EMBL:PUA81852.1,
RC ECO:0000313|Proteomes:UP000244867};
RA Keele B.F.;
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PUA81852.1}.
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DR EMBL; PYXZ01000002; PUA81852.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2R7YZS6; -.
DR OrthoDB; 9805351at2; -.
DR Proteomes; UP000244867; Unassembled WGS sequence.
DR GO; GO:0033765; F:steroid dehydrogenase activity, acting on the CH-CH group of donors; IEA:UniProt.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR Gene3D; 1.20.58.100; Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain; 1.
DR Gene3D; 3.90.700.10; Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain; 1.
DR InterPro; IPR003953; FAD-binding_2.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR037099; Fum_R/Succ_DH_flav-like_C_sf.
DR InterPro; IPR015939; Fum_Rdtase/Succ_DH_flav-like_C.
DR InterPro; IPR030664; SdhA/FrdA/AprA.
DR InterPro; IPR011280; Succ_DH/Fum_Rdt_flav_su.
DR InterPro; IPR027477; Succ_DH/fumarate_Rdtase_cat_sf.
DR NCBIfam; TIGR01811; sdhA_Bsu; 1.
DR PANTHER; PTHR11632; SUCCINATE DEHYDROGENASE 2 FLAVOPROTEIN SUBUNIT; 1.
DR PANTHER; PTHR11632:SF53; SUCCINATE DEHYDROGENASE FLAVOPROTEIN SUBUNIT; 1.
DR Pfam; PF00890; FAD_binding_2; 1.
DR Pfam; PF02910; Succ_DH_flav_C; 1.
DR PRINTS; PR00368; FADPNR.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR SUPFAM; SSF46977; Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain; 1.
DR SUPFAM; SSF56425; Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain; 1.
PE 4: Predicted;
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000244867}.
FT DOMAIN 65..476
FT /note="FAD-dependent oxidoreductase 2 FAD binding"
FT /evidence="ECO:0000259|Pfam:PF00890"
FT DOMAIN 537..671
FT /note="Fumarate reductase/succinate dehydrogenase
FT flavoprotein-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02910"
FT REGION 1..41
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 361
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR630664-50"
SQ SEQUENCE 672 AA; 74218 MW; C4EFED8519C09C70 CRC64;
MPDTVTAAEA SQDTPAEMTD DAAGYYTPGE PLVDAKAPTG PIADRWSDRK FEARLVNPSN
RRKLDVIIVG TGLAGASAAA TLGEAGYNVK SFCYQDSPRR AHSIAAQGGI NAAKNYKEDG
DSVHRLFYDT VKGGDYRSRE SNVYRLAEVS TNIIDQCVAQ GVPFAREYGG LLDNRSFGGV
QVSRTFYARG QTGQQLLIGA YQALERQVAA GTVQTFTRHE MLELIVVDGK ARGIVSRDMV
TGAIDTHLAD VVVLASGGYG NVFYLSTNAM GCNVTAAWRA HRKGAYMANP CYTQIHPTCI
PVSGSHQSKL TLMSESLRND GRIWVPKNEA DCDKDPRDIP EADRDYYLER IYPSFGNLVP
RDIASRAAKN VCDEGRGVGP KVDGVRRGVY LDFAAAIERL GRDGITEKYD NLLDMYERIT
GEDPYEVPMR IYPAVHYVMG GVWVDYDLQS TIPGLFVTGE ANFSDHGANR LGASALMQGL
ADGYFVLPHT IRDYLADGPF EKITEDHPAV VEAHTSVKER IDHFLSVNGT RSVDSYHREL
GNIMWEYCGM ERTEDGLKKA IDLIRTLKDD FWRNVKVLGT NESLNQSLEK AGRVADFIEL
GELMCIDALN RRESCGGHFR GESQTEDGEA LRHDDLFAYV AAWEFAGDGE PPVLHKEDLV
YTAIEMKQRS YK
//
