ID   A0A2R7Z2N4_9ACTN        Unreviewed;       320 AA.
AC   A0A2R7Z2N4;
DT   20-JUN-2018, integrated into UniProtKB/TrEMBL.
DT   20-JUN-2018, sequence version 1.
DT   27-MAR-2024, entry version 14.
DE   SubName: Full=Metallophosphoesterase {ECO:0000313|EMBL:PUA82870.1};
GN   ORFNames=C7S10_03965 {ECO:0000313|EMBL:PUA82870.1};
OS   Nocardioides currus.
OC   Bacteria; Actinomycetota; Actinomycetes; Propionibacteriales;
OC   Nocardioidaceae; Nocardioides.
OX   NCBI_TaxID=2133958 {ECO:0000313|EMBL:PUA82870.1, ECO:0000313|Proteomes:UP000244867};
RN   [1] {ECO:0000313|EMBL:PUA82870.1, ECO:0000313|Proteomes:UP000244867}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=IB-3 {ECO:0000313|EMBL:PUA82870.1,
RC   ECO:0000313|Proteomes:UP000244867};
RA   Keele B.F.;
RL   Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PUA82870.1}.
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DR   EMBL; PYXZ01000001; PUA82870.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2R7Z2N4; -.
DR   OrthoDB; 9780884at2; -.
DR   Proteomes; UP000244867; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR   Gene3D; 3.60.21.10; -; 1.
DR   InterPro; IPR004843; Calcineurin-like_PHP_ApaH.
DR   InterPro; IPR029052; Metallo-depent_PP-like.
DR   PANTHER; PTHR31302:SF20; CONSERVED PROTEIN; 1.
DR   PANTHER; PTHR31302; TRANSMEMBRANE PROTEIN WITH METALLOPHOSPHOESTERASE DOMAIN-RELATED; 1.
DR   Pfam; PF00149; Metallophos; 1.
DR   SUPFAM; SSF56300; Metallo-dependent phosphatases; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000244867};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        20..40
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          62..247
FT                   /note="Calcineurin-like phosphoesterase"
FT                   /evidence="ECO:0000259|Pfam:PF00149"
SQ   SEQUENCE   320 AA;  34579 MW;  A2EF66C046216D0D CRC64;
     MAPLWQPCRV PSSEFLRRRV GLTLGAGAAA GLALTTYAAW EARQYTLREV TVPILPAGRP
     ALRVLHLSDI HMAPDQQAKQ EWLRSLADLA PDLVIDTGDN LSHMASVPVV VDSLGPLLDL
     PGVSVFGSND YFSPGWRNPM LYLLPDRGKR NTHTPQLPWR ELKQRFADRG WVHLCNERAT
     ITAAGTTFAL AGVDDPHLEY DDLAAVAGPA DRDADVRLGI THAPYLRVLD QYAADGYDAV
     IAGHTHGGQV CLPGIGALTT NCDLEPARAK GLHRHPAESA PGDPGSAWLH VSAGLGTNPY
     VRLRVACRPE ATLMTLVPRS
//