ID A0A2R8APU0_9RHOB Unreviewed; 665 AA.
AC A0A2R8APU0;
DT 20-JUN-2018, integrated into UniProtKB/TrEMBL.
DT 20-JUN-2018, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=DNA 3'-5' helicase II {ECO:0000256|ARBA:ARBA00034923};
GN Name=uvrD_1 {ECO:0000313|EMBL:SPF78098.1};
GN ORFNames=PRI8871_00689 {ECO:0000313|EMBL:SPF78098.1};
OS Pseudoprimorskyibacter insulae.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Paracoccaceae; Pseudoprimorskyibacter.
OX NCBI_TaxID=1695997 {ECO:0000313|EMBL:SPF78098.1, ECO:0000313|Proteomes:UP000244904};
RN [1] {ECO:0000313|Proteomes:UP000244904}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CECT 8871 {ECO:0000313|Proteomes:UP000244904};
RA Rodrigo-Torres L., Arahal R. D., Lucena T.;
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Couples ATP hydrolysis with the unwinding of duplex DNA by
CC translocating in the 3'-5' direction.; EC=5.6.2.4;
CC Evidence={ECO:0000256|ARBA:ARBA00034617};
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DR EMBL; OMOJ01000001; SPF78098.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2R8APU0; -.
DR OrthoDB; 384988at2; -.
DR Proteomes; UP000244904; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-UniRule.
DR Gene3D; 1.10.10.160; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR013986; DExx_box_DNA_helicase_dom_sf.
DR InterPro; IPR000212; DNA_helicase_UvrD/REP.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR014016; UvrD-like_ATP-bd.
DR PANTHER; PTHR11070:SF2; ATP-DEPENDENT DNA HELICASE SRS2; 1.
DR PANTHER; PTHR11070; UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER; 1.
DR Pfam; PF00580; UvrD-helicase; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51198; UVRD_HELICASE_ATP_BIND; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00560}; Reference proteome {ECO:0000313|Proteomes:UP000244904}.
FT DOMAIN 28..309
FT /note="UvrD-like helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51198"
FT BINDING 49..56
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00560"
SQ SEQUENCE 665 AA; 74606 MW; A42F603443ACB6FC CRC64;
MIELPEVSDQ DVQWACKVLG LPETAFSGPD GADPRLGVLR ANATLDVEAC PGSGKTTLLV
AKLAILARHW NAAERGICVL SHTNAARREI EKKLGATSEG QRLLSYPHYV GTIHGFVNEY
LALPWLRSKG IKIEAVDDDV CLKWRWSKLP FVTRRALEQR QGSLHRLRYL NSDFDLGAIP
WGKGGVLNRA SATYQHMQRV CQDSYKAGLF CHDEMFVWAS DLLDRYPEVT RHLRHRFPLL
MIDEVQDNSE VQSRLLQRIF VVGGHAVMRQ RFGDQNQAIY SYQGQDGAAT DSFPIEDIKR
TIPNSYRFGN SVAALADPLG VSPHGLVGQG GVGRSGEPEL VGRHAIFLLD DDSVERVIDE
YVAYLRQEFG AAELSSGDFT AVGAVHRADT DDKLPRSIRH YWPEYDPEIS SAEPQPNTLL
QYLAAGRRLA ELSGETNDLV EKLAEGVLRL ARLMSPETAI GKRRRNHRYV MDLLEGNADA
LETYLYLVRA FAVSRVFPTQ DRWEADYRVL FESVAHSLSA SHATNSAANG FLAWSEIGNV
DAAKAKRNNV LWDETQAPAI KVRVGSIHSV KGETHTATLV LETFYYKHHL KELKPWLLGQ
TQGGNGRTDR IKQRLRLHYV AMTRAARLLC LAMRTDAFNE AEIGILRENG WRVARVTQEG
VEWFE
//
