ID   A0A2R8B2V7_9RHOB        Unreviewed;       307 AA.
AC   A0A2R8B2V7;
DT   20-JUN-2018, integrated into UniProtKB/TrEMBL.
DT   20-JUN-2018, sequence version 1.
DT   24-JAN-2024, entry version 12.
DE   SubName: Full=Prephenate dehydrogenase {ECO:0000313|EMBL:SPH16964.1};
DE            EC=1.3.1.12 {ECO:0000313|EMBL:SPH16964.1};
GN   Name=tyrA_1 {ECO:0000313|EMBL:SPH16964.1};
GN   ORFNames=DEA8626_00478 {ECO:0000313|EMBL:SPH16964.1};
OS   Defluviimonas aquaemixtae.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC   Paracoccaceae; Defluviimonas.
OX   NCBI_TaxID=1542388 {ECO:0000313|EMBL:SPH16964.1, ECO:0000313|Proteomes:UP000244924};
RN   [1] {ECO:0000313|EMBL:SPH16964.1, ECO:0000313|Proteomes:UP000244924}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CECT 8626 {ECO:0000313|EMBL:SPH16964.1,
RC   ECO:0000313|Proteomes:UP000244924};
RA   Keele B.F.;
RL   Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; OMOQ01000001; SPH16964.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2R8B2V7; -.
DR   OrthoDB; 9802008at2; -.
DR   Proteomes; UP000244924; Unassembled WGS sequence.
DR   GO; GO:0070403; F:NAD+ binding; IEA:InterPro.
DR   GO; GO:0008977; F:prephenate dehydrogenase (NAD+) activity; IEA:UniProtKB-EC.
DR   GO; GO:0004665; F:prephenate dehydrogenase (NADP+) activity; IEA:InterPro.
DR   GO; GO:0006571; P:tyrosine biosynthetic process; IEA:InterPro.
DR   Gene3D; 1.10.3660.10; 6-phosphogluconate dehydrogenase C-terminal like domain; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR046825; PDH_C.
DR   InterPro; IPR046826; PDH_N.
DR   InterPro; IPR003099; Prephen_DH.
DR   PANTHER; PTHR21363; PREPHENATE DEHYDROGENASE; 1.
DR   PANTHER; PTHR21363:SF0; PREPHENATE DEHYDROGENASE [NADP(+)]; 1.
DR   Pfam; PF20463; PDH_C; 1.
DR   Pfam; PF02153; PDH_N; 1.
DR   SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR   PROSITE; PS51176; PDH_ADH; 1.
PE   4: Predicted;
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW   ECO:0000313|EMBL:SPH16964.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000244924}.
FT   DOMAIN          7..295
FT                   /note="Prephenate/arogenate dehydrogenase"
FT                   /evidence="ECO:0000259|PROSITE:PS51176"
SQ   SEQUENCE   307 AA;  33037 MW;  BE3AB7534BFA34AA CRC64;
     MTAPIYERVA LIGLGLIASS MGHAMKKWGL ATTVTGHAKT ELTRTSALEL GFCDEVFASA
     AEAVRDADLV VLAVPVGAME GVATEIGPHL KPGATVTDVG SVKQAVIEAV APNIPEGVHF
     IPGHPLAGTE HSGPRSGFAT LFRNRFCLLI PNGAAPEAIA RLRDYWEGMG ANVEEMDAAH
     HDIVLAVTSH TPHLIAYTMV GVADHLRRVT ESEIIKYSAA GFRDFTRIAA SDPTMWRDVF
     LTNKEATLDI LGRFTEELFA LQRAIRMGDG DELFDYFTRT RAIRRSIIEA GQDTAAPDFG
     RAKVDGA
//