ID A0A2R8M2A9_CALJA Unreviewed; 69 AA.
AC A0A2R8M2A9;
DT 20-JUN-2018, integrated into UniProtKB/TrEMBL.
DT 25-MAY-2022, sequence version 3.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=Interleukin-7 {ECO:0000256|ARBA:ARBA00019460};
GN Name=IL7 {ECO:0000313|Ensembl:ENSCJAP00000052591.3};
OS Callithrix jacchus (White-tufted-ear marmoset).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Cebidae;
OC Callitrichinae; Callithrix; Callithrix.
OX NCBI_TaxID=9483 {ECO:0000313|Ensembl:ENSCJAP00000052591.3, ECO:0000313|Proteomes:UP000008225};
RN [1] {ECO:0000313|Ensembl:ENSCJAP00000052591.3}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Warren W., Ye L., Minx P., Worley K., Gibbs R., Wilson R.K.;
RL Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSCJAP00000052591.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC -!- SIMILARITY: Belongs to the IL-7/IL-9 family.
CC {ECO:0000256|ARBA:ARBA00007621}.
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DR AlphaFoldDB; A0A2R8M2A9; -.
DR Ensembl; ENSCJAT00000074754.3; ENSCJAP00000052591.3; ENSCJAG00000000494.5.
DR GeneTree; ENSGT00390000004451; -.
DR Proteomes; UP000008225; Chromosome 16.
DR Bgee; ENSCJAG00000000494; Expressed in liver and 2 other cell types or tissues.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0008083; F:growth factor activity; IEA:InterPro.
DR GO; GO:0005139; F:interleukin-7 receptor binding; IEA:InterPro.
DR GO; GO:0006955; P:immune response; IEA:InterPro.
DR Gene3D; 1.20.1250.50; -; 1.
DR InterPro; IPR001181; IL-7.
DR InterPro; IPR038325; IL7_sf.
DR PANTHER; PTHR48404; INTERLEUKIN-7; 1.
DR PANTHER; PTHR48404:SF1; INTERLEUKIN-7; 1.
DR Pfam; PF01415; IL7; 1.
DR PRINTS; PR00435; INTERLEUKIN7.
PE 3: Inferred from homology;
KW Cytokine {ECO:0000256|ARBA:ARBA00022514};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Growth factor {ECO:0000256|ARBA:ARBA00023030};
KW Reference proteome {ECO:0000313|Proteomes:UP000008225};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..25
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 26..69
FT /note="Interleukin-7"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5035218568"
SQ SEQUENCE 69 AA; 7927 MW; BCDBB84B85178562 CRC64;
MFHVSFRYIF GLPPLILVLL PVASSDCDIE GKDGKQYESV LMISIDQLLT QFYKNEKTER
KQKSAMSNN
//
