ID   A0A2R8MBQ9_CALJA        Unreviewed;       192 AA.
AC   A0A2R8MBQ9;
DT   20-JUN-2018, integrated into UniProtKB/TrEMBL.
DT   25-MAY-2022, sequence version 2.
DT   27-MAR-2024, entry version 20.
DE   RecName: Full=Quinone oxidoreductase {ECO:0000256|ARBA:ARBA00039192};
DE            EC=1.6.5.5 {ECO:0000256|ARBA:ARBA00038919};
DE   AltName: Full=NADPH:quinone reductase {ECO:0000256|ARBA:ARBA00043088};
DE   AltName: Full=Zeta-crystallin {ECO:0000256|ARBA:ARBA00042763};
OS   Callithrix jacchus (White-tufted-ear marmoset).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Cebidae;
OC   Callitrichinae; Callithrix; Callithrix.
OX   NCBI_TaxID=9483 {ECO:0000313|Ensembl:ENSCJAP00000057012.2, ECO:0000313|Proteomes:UP000008225};
RN   [1] {ECO:0000313|Ensembl:ENSCJAP00000057012.2}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Warren W., Ye L., Minx P., Worley K., Gibbs R., Wilson R.K.;
RL   Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSCJAP00000057012.2}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=2 a quinone + H(+) + NADPH = 2 a 1,4-benzosemiquinone +
CC         NADP(+); Xref=Rhea:RHEA:14269, ChEBI:CHEBI:15378, ChEBI:CHEBI:57783,
CC         ChEBI:CHEBI:58349, ChEBI:CHEBI:132124, ChEBI:CHEBI:134225;
CC         EC=1.6.5.5; Evidence={ECO:0000256|ARBA:ARBA00036756};
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DR   AlphaFoldDB; A0A2R8MBQ9; -.
DR   Ensembl; ENSCJAT00000069966.2; ENSCJAP00000057012.2; ENSCJAG00000006521.5.
DR   GeneTree; ENSGT00940000154882; -.
DR   Proteomes; UP000008225; Chromosome 7.
DR   Bgee; ENSCJAG00000006521; Expressed in liver and 6 other cell types or tissues.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   CDD; cd08253; zeta_crystallin; 1.
DR   Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR013149; ADH-like_C.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR020843; PKS_ER.
DR   InterPro; IPR002364; Quin_OxRdtase/zeta-crystal_CS.
DR   PANTHER; PTHR44154; QUINONE OXIDOREDUCTASE; 1.
DR   PANTHER; PTHR44154:SF1; QUINONE OXIDOREDUCTASE; 1.
DR   Pfam; PF00107; ADH_zinc_N; 1.
DR   SMART; SM00829; PKS_ER; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR   PROSITE; PS01162; QOR_ZETA_CRYSTAL; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000008225}.
FT   DOMAIN          1..190
FT                   /note="Enoyl reductase (ER)"
FT                   /evidence="ECO:0000259|SMART:SM00829"
SQ   SEQUENCE   192 AA;  20486 MW;  F643FD336187DC31 CRC64;
     MHLLSSARVK AGESVLVHGA SGGVGLAACQ IARAYGLKVL GTAGTEEGQK VVLQNGAHEV
     FNHREVNYID KIKTYVGEKG IDVIIEMLAN VNLSKDLSLL SQGGRVIVVG NRGTIEINPR
     DIMIKESSII GVTLFAITKE EFQQYAAALQ AGMEIGWLKP VIGSQYPLEK VAQAHENIIH
     GSGATGKMIL LL
//