ID A0A2R8MK74_CALJA Unreviewed; 633 AA.
AC A0A2R8MK74;
DT 20-JUN-2018, integrated into UniProtKB/TrEMBL.
DT 20-JUN-2018, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Kirre like nephrin family adhesion molecule 2 {ECO:0000313|Ensembl:ENSCJAP00000060993.1};
GN Name=KIRREL2 {ECO:0000313|Ensembl:ENSCJAP00000060993.1};
OS Callithrix jacchus (White-tufted-ear marmoset).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Cebidae;
OC Callitrichinae; Callithrix; Callithrix.
OX NCBI_TaxID=9483 {ECO:0000313|Ensembl:ENSCJAP00000060993.1, ECO:0000313|Proteomes:UP000008225};
RN [1] {ECO:0000313|Ensembl:ENSCJAP00000060993.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Warren W., Ye L., Minx P., Worley K., Gibbs R., Wilson R.K.;
RL Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSCJAP00000060993.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-
CC pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
CC -!- SIMILARITY: Belongs to the immunoglobulin superfamily.
CC {ECO:0000256|ARBA:ARBA00008637}.
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DR AlphaFoldDB; A0A2R8MK74; -.
DR Ensembl; ENSCJAT00000081313.3; ENSCJAP00000060993.1; ENSCJAG00000009900.5.
DR GeneTree; ENSGT00940000160603; -.
DR Proteomes; UP000008225; Chromosome 22.
DR Bgee; ENSCJAG00000009900; Expressed in ovary and 1 other cell type or tissue.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProt.
DR Gene3D; 2.60.40.10; Immunoglobulins; 5.
DR InterPro; IPR013162; CD80_C2-set.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR013098; Ig_I-set.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR PANTHER; PTHR11640:SF51; KIN OF IRRE-LIKE PROTEIN 2; 1.
DR PANTHER; PTHR11640; NEPHRIN; 1.
DR Pfam; PF08205; C2-set_2; 1.
DR Pfam; PF07679; I-set; 1.
DR Pfam; PF13927; Ig_3; 1.
DR SMART; SM00409; IG; 5.
DR SMART; SM00408; IGc2; 3.
DR SUPFAM; SSF48726; Immunoglobulin; 5.
DR PROSITE; PS50835; IG_LIKE; 5.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000008225};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..633
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5015315173"
FT TRANSMEM 511..534
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 24..118
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 123..222
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 227..307
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 312..394
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 398..501
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT REGION 545..633
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 561..592
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 633 AA; 67062 MW; 806C9C0137104982 CRC64;
TLRMRVPALL ILLVCFRGRA GPSPHFLQQP EDLVVLLGEE ARLQCALGAY WGLVQWTKSG
LALGGQRDLP GWSRYWISGN AAKGQHDLHI RPVELEDEAS YECQATQAGL RSRPAQLHVL
VPPEAPQVLG GPSVSLVAGI PANLTCRSRG DARPIPELLW FRDGVRLDGI TFHQTLLKEG
TPESVESTLT LTPSSHDDGA TLVCRARSQA LPAGRDTAIT LSLQYPPEVT LSAAPHTVQE
GEKVTFLCHA TAQPPVTGYR WAKGGSPVLG ARGPRLEVVA DASFLTEPVS CEVSNAVGSA
NRTTALDVLF GPILQAKPEP VSVDVGEDAS FICAWRGNPL PRVTWIRRGG AQVLGSGPTL
RLPSVGPEDA GDYVCRAEPG LSGRGGGAAE ARLTVNAPPV VTALHSAPAF LRGPARLQCL
VFASPAPDAV VWSWDEGFLE AGSRGRFLVE TFPAPEGHEG QGPGLISVLH ISGTQESDFS
RSFNCSARNR LGEGGARASL GRRDLLPTVR IVAGVAAATT TLLMVITGVA LCCWRHGKAS
ASFPEQKNLM RIPGSSDGSS SRGPEEEETG SGEDRGPIVH TDHSDLVLEE EGALQTKDPT
NGYYKVRGVS PPAPPNSCVT SLQWKSPGIS ILP
//
