ID A0A2R8MUA2_CALJA Unreviewed; 969 AA.
AC A0A2R8MUA2;
DT 20-JUN-2018, integrated into UniProtKB/TrEMBL.
DT 11-DEC-2019, sequence version 2.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=General vesicular transport factor p115 {ECO:0000256|ARBA:ARBA00018243};
GN Name=USO1 {ECO:0000313|Ensembl:ENSCJAP00000065093.2};
OS Callithrix jacchus (White-tufted-ear marmoset).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Cebidae;
OC Callitrichinae; Callithrix; Callithrix.
OX NCBI_TaxID=9483 {ECO:0000313|Ensembl:ENSCJAP00000065093.2, ECO:0000313|Proteomes:UP000008225};
RN [1] {ECO:0000313|Ensembl:ENSCJAP00000065093.2}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Warren W., Ye L., Minx P., Worley K., Gibbs R., Wilson R.K.;
RL Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSCJAP00000065093.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004170};
CC Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004170}.
CC -!- SIMILARITY: Belongs to the VDP/USO1/EDE1 family.
CC {ECO:0000256|ARBA:ARBA00006960}.
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DR RefSeq; XP_008991414.1; XM_008993166.2.
DR AlphaFoldDB; A0A2R8MUA2; -.
DR Ensembl; ENSCJAT00000086091.3; ENSCJAP00000065093.2; ENSCJAG00000019852.5.
DR GeneID; 100412915; -.
DR CTD; 8615; -.
DR GeneTree; ENSGT00390000017018; -.
DR OrthoDB; 1774at2759; -.
DR Proteomes; UP000008225; Chromosome 3.
DR Bgee; ENSCJAG00000019852; Expressed in ovary and 6 other cell types or tissues.
DR GO; GO:0000139; C:Golgi membrane; IEA:InterPro.
DR GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR GO; GO:0048280; P:vesicle fusion with Golgi apparatus; IEA:InterPro.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR000225; Armadillo.
DR InterPro; IPR041209; P115_Arm_rpt.
DR InterPro; IPR006955; Uso1_p115_C.
DR InterPro; IPR006953; Vesicle_Uso1_P115_head.
DR PANTHER; PTHR10013; GENERAL VESICULAR TRANSPORT FACTOR P115; 1.
DR PANTHER; PTHR10013:SF0; GENERAL VESICULAR TRANSPORT FACTOR P115; 1.
DR Pfam; PF18770; Arm_vescicular; 1.
DR Pfam; PF04871; Uso1_p115_C; 1.
DR Pfam; PF04869; Uso1_p115_head; 1.
DR SMART; SM00185; ARM; 3.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR PROSITE; PS50176; ARM_REPEAT; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Golgi apparatus {ECO:0000256|ARBA:ARBA00023034};
KW Reference proteome {ECO:0000313|Proteomes:UP000008225};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT REPEAT 60..97
FT /note="ARM"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
FT DOMAIN 347..635
FT /note="Vesicle tethering protein Uso1/P115-like head"
FT /evidence="ECO:0000259|Pfam:PF04869"
FT DOMAIN 793..958
FT /note="Uso1/p115-like vesicle tethering protein C-terminal"
FT /evidence="ECO:0000259|Pfam:PF04871"
FT REGION 933..969
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 659..707
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 739..828
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 857..912
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 943..962
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 969 AA; 108713 MW; DBCDF2D486DAC12B CRC64;
MNFLRGVMGG QSAGPQHTEA ETIQKLCDRV ASSTLLDDRR NAVRALKSLS KKYRLEVGIQ
AMEHLIHVLQ TDRSDSEIIG YALDTLYNII SNDEEEEVEE NSTRQSEDLG SQFTEIFIKQ
QENVTLLLSL LEEFDFHVRW PGVKLLTSLL KQLGPQVQQI ILVSPMGVSR LMDLLADSRE
VIRNDGVLLL QALTRSNGAI QKIVAFENAF ERLLDIITEE GSSDGGIVVE DCLLLLQNLL
KNNNSNQNFF KEGSYIQRMK PWFEVGDENS GWSAQKVTNL HLMLQLVRVL VSPTNPPGAT
SSCQKAMFQC GLLQQLCTIL MATGVPADIL TETINTVSEV IRGCQVNQDY FASVNAPSNP
PRPAIVVLLM SMVNERQPFV LRCAVLYCFQ CFLYKNQKGQ GEIVSTLLPS TIDATGNSVS
AGQLLCGGLF STDSLSNWCA AVALAHALQE NATQKEQLLR VQLATSIGNP PVSLLQQCTN
ILSQGDKIDR RGSKIQTRVG LLMLLCTWLS NCPIAVTHFL HNSANVPFLT GQIAENLGEE
EQLVQGLCAL LLGISIYFND NSLESYMKEK LKQLIEKRIG KENFIEKLGF ISKHELYSRA
SQKPQPNFPS PEYMIFDHEF TKLVKELEGV ITKAIYKSSE EDKKEEEVKK TLEQHDNIVT
HYKNMIREQD LQLEELRQQV STLKCQNEQL QTAVTQQVSQ IQQHKDQYNL LKIQLGKDNQ
HQGSYSEGAQ MNGIQPEEIS RLREEIEELK RNRELLQSQL TEKDSVIENL KSSQTSGTNE
QSSAIASARD FEEVAELKQE LATLKSQLNS QSVEITKLQT EKQELLQKTE AFAKSAEVQG
ESETVIATKT TDVEGRLSAL LQETKELKNE IKALSEERTA IKEQLDSSNS TIAILQTEKD
KLELEITDSK KEQDDLLVLL ADQDQKILSL KNKLKDLGHP VEEEDELESG DQEDEDDESE
DPGKDLDRI
//
