ID   A0A2R8MZ10_CALJA        Unreviewed;       575 AA.
AC   A0A2R8MZ10;
DT   20-JUN-2018, integrated into UniProtKB/TrEMBL.
DT   11-DEC-2019, sequence version 2.
DT   27-MAR-2024, entry version 31.
DE   RecName: Full=SHC-transforming protein 1 {ECO:0000256|ARBA:ARBA00020297};
DE   AltName: Full=Src homology 2 domain-containing-transforming protein C1 {ECO:0000256|ARBA:ARBA00031530};
GN   Name=SHC1 {ECO:0000313|Ensembl:ENSCJAP00000067068.2};
OS   Callithrix jacchus (White-tufted-ear marmoset).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Cebidae;
OC   Callitrichinae; Callithrix; Callithrix.
OX   NCBI_TaxID=9483 {ECO:0000313|Ensembl:ENSCJAP00000067068.2, ECO:0000313|Proteomes:UP000008225};
RN   [1] {ECO:0000313|Ensembl:ENSCJAP00000067068.2}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Warren W., Ye L., Minx P., Worley K., Gibbs R., Wilson R.K.;
RL   Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSCJAP00000067068.2}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
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DR   AlphaFoldDB; A0A2R8MZ10; -.
DR   Ensembl; ENSCJAT00000076313.3; ENSCJAP00000067068.2; ENSCJAG00000009236.5.
DR   GeneTree; ENSGT00950000182870; -.
DR   Proteomes; UP000008225; Chromosome 18.
DR   Bgee; ENSCJAG00000009236; Expressed in ovary and 6 other cell types or tissues.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   CDD; cd01209; PTB_Shc; 1.
DR   CDD; cd09925; SH2_SHC; 1.
DR   Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR   Gene3D; 3.30.505.10; SH2 domain; 1.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   InterPro; IPR006019; PID_Shc-like.
DR   InterPro; IPR006020; PTB/PI_dom.
DR   InterPro; IPR000980; SH2.
DR   InterPro; IPR036860; SH2_dom_sf.
DR   InterPro; IPR035676; SHC_SH2.
DR   PANTHER; PTHR10337; SHC TRANSFORMING PROTEIN; 1.
DR   PANTHER; PTHR10337:SF2; SHC-TRANSFORMING PROTEIN 1; 1.
DR   Pfam; PF00640; PID; 1.
DR   Pfam; PF00017; SH2; 1.
DR   PRINTS; PR00401; SH2DOMAIN.
DR   PRINTS; PR00629; SHCPIDOMAIN.
DR   SMART; SM00462; PTB; 1.
DR   SMART; SM00252; SH2; 1.
DR   SUPFAM; SSF50729; PH domain-like; 1.
DR   SUPFAM; SSF55550; SH2 domain; 1.
DR   PROSITE; PS01179; PID; 1.
DR   PROSITE; PS50001; SH2; 1.
PE   4: Predicted;
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Growth regulation {ECO:0000256|ARBA:ARBA00022604};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008225};
KW   SH2 domain {ECO:0000256|ARBA:ARBA00022999, ECO:0000256|PROSITE-
KW   ProRule:PRU00191}.
FT   DOMAIN          156..337
FT                   /note="PID"
FT                   /evidence="ECO:0000259|PROSITE:PS01179"
FT   DOMAIN          480..571
FT                   /note="SH2"
FT                   /evidence="ECO:0000259|PROSITE:PS50001"
FT   REGION          1..92
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          335..355
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          428..450
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        13..36
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   575 AA;  61884 MW;  849C040BDEB704B6 CRC64;
     MDLLPPKPKY NPLRNESLSS LEEGASGSTP PEELPSPSAS SLGPILPPLP GDDSPTTLCS
     FFPRMSNLRL ANPAGGRPGP KGEPGRAADD GEGIVGAAMP DSGPLPLLQD MNKLSGGGGR
     RTRVEGGQLG GEEWTRHGSF VNKPTRGWLH PNDKVMGPGV CYLVRYMGCV EVLQSMRALD
     FNTRTQVTRE AISLVCEAVP GAKGATRRRK PCSRPLSSIL GRSNLKFAGM PITLTISTSS
     LNLMAADCKQ IIANHHMQSI SFASGGDPVS WGTDSMTASA VPSACHILEC PEGLAQDVIS
     TIGQAFELRF KQYLRNPPKL VTPHDRMAGF DGSAWDEEEE EPPDHQYYND FPGKEPPLGG
     VVDMRLREGA TPPTAQTPSH LGATLPIGQP VGGDPEVRKQ MPLPPPCPAG RELFDDPSYV
     NVQNLDKARQ AGGGAGPPNP AINGSAPRDL FDMKPFEDAL RVPPPPQSVT MAEQLRGEPW
     FHGKLSRREA EALLQLNGDF LVRESTTTPG QYVLTGLQSG QPKHLLLVDP EGVVRTKDHR
     FESVSHLISY HMDNHLPIIS AGSELCLQQP VERKL
//