ID A0A2R8PCQ3_CALJA Unreviewed; 851 AA.
AC A0A2R8PCQ3;
DT 20-JUN-2018, integrated into UniProtKB/TrEMBL.
DT 25-MAY-2022, sequence version 3.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=Dipeptidyl aminopeptidase-like protein 6 {ECO:0000256|ARBA:ARBA00040948};
DE AltName: Full=Dipeptidyl peptidase 6 {ECO:0000256|ARBA:ARBA00042016};
DE AltName: Full=Dipeptidyl peptidase VI {ECO:0000256|ARBA:ARBA00041991};
GN Name=DPP6 {ECO:0000313|Ensembl:ENSCJAP00000060829.3};
OS Callithrix jacchus (White-tufted-ear marmoset).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Cebidae;
OC Callitrichinae; Callithrix; Callithrix.
OX NCBI_TaxID=9483 {ECO:0000313|Ensembl:ENSCJAP00000060829.3, ECO:0000313|Proteomes:UP000008225};
RN [1] {ECO:0000313|Ensembl:ENSCJAP00000060829.3}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Warren W., Ye L., Minx P., Worley K., Gibbs R., Wilson R.K.;
RL Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSCJAP00000060829.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; A0A2R8PCQ3; -.
DR Ensembl; ENSCJAT00000073170.3; ENSCJAP00000060829.3; ENSCJAG00000000167.5.
DR GeneTree; ENSGT00940000156280; -.
DR Proteomes; UP000008225; Chromosome 8.
DR Bgee; ENSCJAG00000000167; Expressed in cerebellum and 3 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008236; F:serine-type peptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR Gene3D; 2.140.10.30; Dipeptidylpeptidase IV, N-terminal domain; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR001375; Peptidase_S9.
DR InterPro; IPR002469; Peptidase_S9B_N.
DR PANTHER; PTHR11731:SF20; DIPEPTIDYL AMINOPEPTIDASE-LIKE PROTEIN 6; 1.
DR PANTHER; PTHR11731; PROTEASE FAMILY S9B,C DIPEPTIDYL-PEPTIDASE IV-RELATED; 1.
DR Pfam; PF00930; DPPIV_N; 1.
DR Pfam; PF00326; Peptidase_S9; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR SUPFAM; SSF82171; DPP6 N-terminal domain-like; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000008225};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 86..107
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 185..547
FT /note="Dipeptidylpeptidase IV N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00930"
FT DOMAIN 628..834
FT /note="Peptidase S9 prolyl oligopeptidase catalytic"
FT /evidence="ECO:0000259|Pfam:PF00326"
SQ SEQUENCE 851 AA; 96821 MW; FA8604D47D24C1C7 CRC64;
MDVNKGKDGW AWWLTPIIPA LWEAKVGRSF KVRCSRPAWP TWGNLISTKN ITNISWARWW
VPVIPATQEA EELVGSNPPQ RNWKGIAIAL LVILVICSLI VTSVILLTPA EDNSLSQKKK
VTVEDLFSED LKIHDPEAKW ISDTEFIYRE QKGTVRLWNV ETNISTVLIE GKKIESLRAI
RYEISPDREY ALFSYNVEPI YQHSYTGYYV LSKIPHGDPQ SLDPPEVSNA KLQYAGWGPK
GQQLIFIFEN NIYYCAHVGK QAIRVVSTGK EGVIYNGLSD WLYEEEILKT HIAHWWSPDG
TRLAYATIND SRVPLMELPT YTGSIYPTVK PYHYPKAGSE NPSISLHVIG LNGPTHDLEM
MPPDDPRMRE YYITMVKWAT STKVAVTWLN RAQNVSILTL CDATTGVCTK VWGWGEVAGN
EEPVFSKDGR KFFFVRAIPQ GGRGKFYHIT VSASQPNSSN DNIQSITSGD WDVTKILAYD
EKGNKIYFLS TEDLPRRRQL YSANTVGNFN RQCLSCDLVE NCTYFSASFS HSMEFFLLKC
EGPGVPMVTV HNTTDKKKMF DLETNEHVKK AIHDRQMPKV EYRTIEIDDY NLPMQILKPA
TFTDTTHYPL LLVVDGTPGS QSVAEKFEVS WETVMVSSHG AMVLKCDGRG SGFQGTKLLH
EVRRRLGLLE EKDQMEAVRT MLKEQYIDRT RVAVFGKDYG GYLSTYILPA KGENQGQMFT
CGSAVSPITD FKLYASAFSE RYLGLHGLDN RAYEMTKVAH RVSALEEQQF LIIHATADEK
IHFQHTAELI THLIRGKANY SLQIYPDESH YFTSTTLKQH LFRSIINFFV ECFRIQDKLL
AATAKEDEEE D
//
