ID A0A2R8ZC15_PANPA Unreviewed; 141 AA.
AC A0A2R8ZC15;
DT 20-JUN-2018, integrated into UniProtKB/TrEMBL.
DT 20-JUN-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=SH3 domain-binding glutamic acid-rich-like protein 3 {ECO:0000256|ARBA:ARBA00040886};
OS Pan paniscus (Pygmy chimpanzee) (Bonobo).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pan.
OX NCBI_TaxID=9597 {ECO:0000313|Ensembl:ENSPPAP00000002600.1, ECO:0000313|Proteomes:UP000240080};
RN [1] {ECO:0000313|Ensembl:ENSPPAP00000002600.1, ECO:0000313|Proteomes:UP000240080}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=22722832; DOI=10.1038/nature11128;
RA Prufer K., Munch K., Hellmann I., Akagi K., Miller J.R., Walenz B.,
RA Koren S., Sutton G., Kodira C., Winer R., Knight J.R., Mullikin J.C.,
RA Meader S.J., Ponting C.P., Lunter G., Higashino S., Hobolth A., Dutheil J.,
RA Karakoc E., Alkan C., Sajjadian S., Catacchio C.R., Ventura M.,
RA Marques-Bonet T., Eichler E.E., Andre C., Atencia R., Mugisha L.,
RA Junhold J., Patterson N., Siebauer M., Good J.M., Fischer A., Ptak S.E.,
RA Lachmann M., Symer D.E., Mailund T., Schierup M.H., Andres A.M., Kelso J.,
RA Paabo S.;
RT "The bonobo genome compared with the chimpanzee and human genomes.";
RL Nature 486:527-531(2012).
RN [2] {ECO:0000313|Ensembl:ENSPPAP00000002600.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell projection, ruffle membrane
CC {ECO:0000256|ARBA:ARBA00004632}. Membrane
CC {ECO:0000256|ARBA:ARBA00004370}. Nucleus
CC {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the SH3BGR family.
CC {ECO:0000256|ARBA:ARBA00007764}.
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DR EMBL; AJFE02029131; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A2R8ZC15; -.
DR Ensembl; ENSPPAT00000012383.1; ENSPPAP00000002600.1; ENSPPAG00000011359.1.
DR GeneTree; ENSGT00940000157260; -.
DR Proteomes; UP000240080; Chromosome 1.
DR Bgee; ENSPPAG00000011359; Expressed in placenta and 6 other cell types or tissues.
DR GO; GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0032587; C:ruffle membrane; IEA:UniProtKB-SubCell.
DR CDD; cd03030; GRX_SH3BGR; 1.
DR Gene3D; 3.40.30.10; Glutaredoxin; 1.
DR InterPro; IPR006993; Glut_rich_SH3-bd.
DR InterPro; IPR036249; Thioredoxin-like_sf.
DR PANTHER; PTHR12232; SH3 DOMAIN-BINDING GLUTAMIC ACID-RICH-LIKE PROTEIN; 1.
DR PANTHER; PTHR12232:SF3; SH3 DOMAIN-BINDING GLUTAMIC ACID-RICH-LIKE PROTEIN 3; 1.
DR Pfam; PF04908; SH3BGR; 1.
DR SUPFAM; SSF52833; Thioredoxin-like; 1.
DR PROSITE; PS51354; GLUTAREDOXIN_2; 1.
PE 3: Inferred from homology;
KW Acetylation {ECO:0000256|ARBA:ARBA00022990};
KW Cell projection {ECO:0000256|ARBA:ARBA00023273};
KW Reference proteome {ECO:0000313|Proteomes:UP000240080}.
FT REGION 98..120
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 141 AA; 15600 MW; 5FBDF1D5F8C362B1 CRC64;
MSGLRVYSTS VTGSREVSIK SQQSEVTRIL DGKRIQYQLV DISQDNALRD EMRALAGNPK
ATPPQIVNGD QYCGDYELFV EAVEQNTLQD QACPEFPCWT PSPHSPQPSP GHEGPFDQLP
VIPNLTLESL PQCRPLLLPP L
//
