ID A0A2R8ZFB3_PANPA Unreviewed; 167 AA.
AC A0A2R8ZFB3;
DT 20-JUN-2018, integrated into UniProtKB/TrEMBL.
DT 20-JUN-2018, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=Sugar transporter SWEET1 {ECO:0000256|ARBA:ARBA00021741};
DE AltName: Full=Solute carrier family 50 member 1 {ECO:0000256|ARBA:ARBA00031430};
GN Name=SLC50A1 {ECO:0000313|Ensembl:ENSPPAP00000003549.1};
OS Pan paniscus (Pygmy chimpanzee) (Bonobo).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pan.
OX NCBI_TaxID=9597 {ECO:0000313|Ensembl:ENSPPAP00000003549.1, ECO:0000313|Proteomes:UP000240080};
RN [1] {ECO:0000313|Ensembl:ENSPPAP00000003549.1, ECO:0000313|Proteomes:UP000240080}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=22722832; DOI=10.1038/nature11128;
RA Prufer K., Munch K., Hellmann I., Akagi K., Miller J.R., Walenz B.,
RA Koren S., Sutton G., Kodira C., Winer R., Knight J.R., Mullikin J.C.,
RA Meader S.J., Ponting C.P., Lunter G., Higashino S., Hobolth A., Dutheil J.,
RA Karakoc E., Alkan C., Sajjadian S., Catacchio C.R., Ventura M.,
RA Marques-Bonet T., Eichler E.E., Andre C., Atencia R., Mugisha L.,
RA Junhold J., Patterson N., Siebauer M., Good J.M., Fischer A., Ptak S.E.,
RA Lachmann M., Symer D.E., Mailund T., Schierup M.H., Andres A.M., Kelso J.,
RA Paabo S.;
RT "The bonobo genome compared with the chimpanzee and human genomes.";
RL Nature 486:527-531(2012).
RN [2] {ECO:0000313|Ensembl:ENSPPAP00000003549.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Golgi apparatus membrane
CC {ECO:0000256|ARBA:ARBA00004653}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004653}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the SWEET sugar transporter family.
CC {ECO:0000256|ARBA:ARBA00007809}.
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DR EMBL; AJFE02058111; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_008968497.1; XM_008970249.1.
DR AlphaFoldDB; A0A2R8ZFB3; -.
DR SMR; A0A2R8ZFB3; -.
DR Ensembl; ENSPPAT00000016314.1; ENSPPAP00000003549.1; ENSPPAG00000014850.1.
DR GeneID; 100988694; -.
DR CTD; 55974; -.
DR GeneTree; ENSGT00390000007801; -.
DR OrthoDB; 66728at2759; -.
DR Proteomes; UP000240080; Chromosome 1.
DR Bgee; ENSPPAG00000014850; Expressed in placenta and 6 other cell types or tissues.
DR GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0051119; F:sugar transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 1.20.1280.290; -; 2.
DR InterPro; IPR047664; SWEET.
DR InterPro; IPR004316; SWEET_rpt.
DR PANTHER; PTHR10791; RAG1-ACTIVATING PROTEIN 1; 1.
DR PANTHER; PTHR10791:SF30; SUGAR TRANSPORTER SWEET1; 1.
DR Pfam; PF03083; MtN3_slv; 2.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000240080};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Sugar transport {ECO:0000256|ARBA:ARBA00022597};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 6..30
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 68..88
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 108..126
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 132..152
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 167 AA; 19020 MW; CCCDF3750BB71D12 CRC64;
MEAGGFLDSL IYGACVVFTL GMFSAGLSDL RHMRMTRSVD NVQFLPFLTT EVNNLGWLSY
GALKGDGILI VVNTVGAALQ TLYILAYLHY CPRKAKVIQT KSTQCLSYPL TIATLLTSAS
WCLYGFRLRD PYIMVSNFPG IVTSFIRFWL FWKYPQEQDR NYWLLQT
//
