ID A0A2R8ZFP6_PANPA Unreviewed; 248 AA.
AC A0A2R8ZFP6;
DT 20-JUN-2018, integrated into UniProtKB/TrEMBL.
DT 20-JUN-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Apolipoprotein L domain containing 1 {ECO:0000313|Ensembl:ENSPPAP00000003832.1};
GN Name=APOLD1 {ECO:0000313|Ensembl:ENSPPAP00000003832.1};
OS Pan paniscus (Pygmy chimpanzee) (Bonobo).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pan.
OX NCBI_TaxID=9597 {ECO:0000313|Ensembl:ENSPPAP00000003832.1, ECO:0000313|Proteomes:UP000240080};
RN [1] {ECO:0000313|Ensembl:ENSPPAP00000003832.1, ECO:0000313|Proteomes:UP000240080}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=22722832; DOI=10.1038/nature11128;
RA Prufer K., Munch K., Hellmann I., Akagi K., Miller J.R., Walenz B.,
RA Koren S., Sutton G., Kodira C., Winer R., Knight J.R., Mullikin J.C.,
RA Meader S.J., Ponting C.P., Lunter G., Higashino S., Hobolth A., Dutheil J.,
RA Karakoc E., Alkan C., Sajjadian S., Catacchio C.R., Ventura M.,
RA Marques-Bonet T., Eichler E.E., Andre C., Atencia R., Mugisha L.,
RA Junhold J., Patterson N., Siebauer M., Good J.M., Fischer A., Ptak S.E.,
RA Lachmann M., Symer D.E., Mailund T., Schierup M.H., Andres A.M., Kelso J.,
RA Paabo S.;
RT "The bonobo genome compared with the chimpanzee and human genomes.";
RL Nature 486:527-531(2012).
RN [2] {ECO:0000313|Ensembl:ENSPPAP00000003832.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the apolipoprotein L family.
CC {ECO:0000256|ARBA:ARBA00010090}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AJFE02026648; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJFE02026649; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJFE02026650; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJFE02026651; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJFE02026652; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJFE02026653; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_003808900.1; XM_003808852.2.
DR AlphaFoldDB; A0A2R8ZFP6; -.
DR Ensembl; ENSPPAT00000017675.1; ENSPPAP00000003832.1; ENSPPAG00000016129.1.
DR GeneID; 100986371; -.
DR KEGG; pps:100986371; -.
DR CTD; 81575; -.
DR GeneTree; ENSGT01030000234599; -.
DR OrthoDB; 5317347at2759; -.
DR Proteomes; UP000240080; Chromosome 12.
DR Bgee; ENSPPAG00000016129; Expressed in heart and 6 other cell types or tissues.
DR GO; GO:0005576; C:extracellular region; IEA:InterPro.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008289; F:lipid binding; IEA:InterPro.
DR GO; GO:0006869; P:lipid transport; IEA:InterPro.
DR GO; GO:0042157; P:lipoprotein metabolic process; IEA:InterPro.
DR InterPro; IPR008405; ApoL.
DR PANTHER; PTHR14096; APOLIPOPROTEIN L; 1.
DR PANTHER; PTHR14096:SF1; APOLIPOPROTEIN L DOMAIN-CONTAINING PROTEIN 1; 1.
DR Pfam; PF05461; ApoL; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000240080};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 53..74
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 86..111
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 248 AA; 27063 MW; 291DE656CDC04338 CRC64;
MGMERPAARE PHGPDALRRF QGLLLDRRGR LHGQVLRLRE VARRLERLRR RSLVANVAGS
SLSATGALAA IVGLSLSPVT LGTSLLVSAV GLGVATAGGA VTITSDLSLI FCNSRELRRV
QEIAATCQDQ MREILSCLEF FCRWQGCGDR QLLQCGRNAS IALYNSVYFI VFFGSRGFLI
PRRAEGDTKV SQAVLKAKIQ KLAESLESCT GALDELSEQL ESRVQLCTKS SRGHDLKISA
DQRAGLFF
//
