ID A0A2R8ZLG0_PANPA Unreviewed; 2062 AA.
AC A0A2R8ZLG0;
DT 20-JUN-2018, integrated into UniProtKB/TrEMBL.
DT 20-JUN-2018, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE SubName: Full=Lipoxygenase homology PLAT domains 1 {ECO:0000313|Ensembl:ENSPPAP00000005794.1};
GN Name=LOXHD1 {ECO:0000313|Ensembl:ENSPPAP00000005794.1};
OS Pan paniscus (Pygmy chimpanzee) (Bonobo).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pan.
OX NCBI_TaxID=9597 {ECO:0000313|Ensembl:ENSPPAP00000005794.1, ECO:0000313|Proteomes:UP000240080};
RN [1] {ECO:0000313|Ensembl:ENSPPAP00000005794.1, ECO:0000313|Proteomes:UP000240080}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=22722832; DOI=10.1038/nature11128;
RA Prufer K., Munch K., Hellmann I., Akagi K., Miller J.R., Walenz B.,
RA Koren S., Sutton G., Kodira C., Winer R., Knight J.R., Mullikin J.C.,
RA Meader S.J., Ponting C.P., Lunter G., Higashino S., Hobolth A., Dutheil J.,
RA Karakoc E., Alkan C., Sajjadian S., Catacchio C.R., Ventura M.,
RA Marques-Bonet T., Eichler E.E., Andre C., Atencia R., Mugisha L.,
RA Junhold J., Patterson N., Siebauer M., Good J.M., Fischer A., Ptak S.E.,
RA Lachmann M., Symer D.E., Mailund T., Schierup M.H., Andres A.M., Kelso J.,
RA Paabo S.;
RT "The bonobo genome compared with the chimpanzee and human genomes.";
RL Nature 486:527-531(2012).
RN [2] {ECO:0000313|Ensembl:ENSPPAP00000005794.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00152}.
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DR EMBL; AJFE02106125; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJFE02106126; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR Ensembl; ENSPPAT00000025964.1; ENSPPAP00000005794.1; ENSPPAG00000023447.1.
DR GeneTree; ENSGT00390000018830; -.
DR Proteomes; UP000240080; Chromosome 18.
DR Bgee; ENSPPAG00000023447; Expressed in testis and 1 other cell type or tissue.
DR CDD; cd01756; PLAT_repeat; 13.
DR Gene3D; 2.40.180.10; Catalase core domain; 8.
DR Gene3D; 2.60.60.20; PLAT/LH2 domain; 7.
DR InterPro; IPR001024; PLAT/LH2_dom.
DR InterPro; IPR036392; PLAT/LH2_dom_sf.
DR PANTHER; PTHR45901:SF6; LIPOXYGENASE HOMOLOGY DOMAIN-CONTAINING PROTEIN 1; 1.
DR PANTHER; PTHR45901; PROTEIN CBG12474; 1.
DR Pfam; PF01477; PLAT; 15.
DR SMART; SM00308; LH2; 12.
DR SUPFAM; SSF49723; Lipase/lipooxygenase domain (PLAT/LH2 domain); 15.
DR PROSITE; PS50095; PLAT; 15.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000240080}.
FT DOMAIN 40..157
FT /note="PLAT"
FT /evidence="ECO:0000259|PROSITE:PS50095"
FT DOMAIN 169..284
FT /note="PLAT"
FT /evidence="ECO:0000259|PROSITE:PS50095"
FT DOMAIN 293..409
FT /note="PLAT"
FT /evidence="ECO:0000259|PROSITE:PS50095"
FT DOMAIN 422..537
FT /note="PLAT"
FT /evidence="ECO:0000259|PROSITE:PS50095"
FT DOMAIN 550..670
FT /note="PLAT"
FT /evidence="ECO:0000259|PROSITE:PS50095"
FT DOMAIN 681..800
FT /note="PLAT"
FT /evidence="ECO:0000259|PROSITE:PS50095"
FT DOMAIN 811..931
FT /note="PLAT"
FT /evidence="ECO:0000259|PROSITE:PS50095"
FT DOMAIN 966..1084
FT /note="PLAT"
FT /evidence="ECO:0000259|PROSITE:PS50095"
FT DOMAIN 1097..1222
FT /note="PLAT"
FT /evidence="ECO:0000259|PROSITE:PS50095"
FT DOMAIN 1251..1369
FT /note="PLAT"
FT /evidence="ECO:0000259|PROSITE:PS50095"
FT DOMAIN 1418..1536
FT /note="PLAT"
FT /evidence="ECO:0000259|PROSITE:PS50095"
FT DOMAIN 1549..1662
FT /note="PLAT"
FT /evidence="ECO:0000259|PROSITE:PS50095"
FT DOMAIN 1674..1792
FT /note="PLAT"
FT /evidence="ECO:0000259|PROSITE:PS50095"
FT DOMAIN 1805..1926
FT /note="PLAT"
FT /evidence="ECO:0000259|PROSITE:PS50095"
FT DOMAIN 1943..2059
FT /note="PLAT"
FT /evidence="ECO:0000259|PROSITE:PS50095"
SQ SEQUENCE 2062 AA; 235092 MW; DCD01D78BF1654B0 CRC64;
QKKRRRKKDI DFLALYEAEL LNYASEDDEG ELEHEYYKAR VYEVVTATGD VRGAGTDANV
FITLFGENGL SPKLQLTSKS KSAFEKGNVD VFRVRTNNVG LIYKVRIEHD NTGLNASWYL
DHVIVTDMKR PHLRYYFNCN NWLSKVEGDR QWCRDLLASF NPMDMPRGNK YEVKVYTGDV
IGAGTDADVF INIFGEYGDT GERRLENEKD NFEKGAEDRF ILDAPDLGQL MKINVGHNNK
GGSAGWFLSQ IVIEDIGNKR KYDFPLNRWL ALDEDDGKIQ RDILVGGAET TAITYIVTVF
TGDVRGAGTK SKIYLIMYGA RGNKNSGKIF LESGVFDRGR TDIFHIELAV LLSPLSRVSI
GHGNVGVNRG WFCEKVVILC PFTGIQQTFP CSNWLDEKKA DGLIERQLYE MVSLRKKRLK
KFPWSLWVWT TDLKKAGTNS PIFIQIYGQK GRTDEILLNP NNKWFKPGII EKFRIELPDL
GRFYKIRVWH DKRSSGSGWH LERMTLMNTL NKDKYNFNCN RWLDANEDDN EIVREMTAEG
PTVHRIMGMA RYHVTVCTGE LEGAGTDANV YLCLFGDVGD TGERLLYNCR NNTDLFEKGN
ADEFTIESVT MRNVRRVRIR HDGKGSGSGW YLDRVLVREE GQPESDNVEF PCLRWLDKDK
DDGQLVRELL PSDSSATLKN FRYHISLKTG DVSGASTDSR VYIKLYGDKS DTIKQVLLVS
DNNLKDYFER GRVDEFTLET LNIGNINRLV IGHDSSGMHA SWFLGSVQIR VPRQGKQYTF
PANRWLDKNQ ADGRLEVELY PSEVVEIQKL VHYEVEIWTG DVGGAGTSAR VYMQIYGEKG
KTEVLFLSSR SKVFERASKD TFQTDTFTIY AIDLGALTKI RIRHDNTGNR AGWFLDRVDI
TDMNNEITYY FPCQRWLAVE EDDGQLSREL LPVDESYVLP QSEEGGGGGD NNPLDNLALE
QKDKSTTFSV TIKTGVKKNA GTDANVFITL FGTQDDTGMT LLKSSKTNSD KFERDSIEIF
TVETLDLGDL WKVRLGHDNT GKAPGWFVDW VEVDAPSLGK CMTFPCGRWL AKNEDDGSII
RDLFHAELQT RLYTPFVPYE ITLYTSDVFA AGTDANIFII IYGCDAMCTQ QKYLCTNKRE
QKQFFERKSA SRFIVELEDV GEIIEKIRIG HNNTGMNPGW HCSHVDIRRL LPDKDGAETL
TFPCDRWLAT SEDDKKTIRE LVPYDIFTEK YMKDGSLRQV YKEVEEPLDI VLYSVQIFTG
NIPGAGTDAK VYITIYGDLG DTGERYLGKS ENRTNKFERG TADTFIIEAA DLGVIYKIKL
RHDNSKWCAD WYVEKVEIWN DTNEDEFLFL CGRWLSLKKE DGRLERLFYE KEYTGDRSSN
CSSPADFWEI ALSSKMADVD ISTVTGPMAD YVQEGPIIPY YVSVTTGKHK DAATDSRAFI
FLIGEDDERS KRIWLDYPRG KRGFSRGSVE EFYIAGLDVG IIKKIELGHD GASPESCWLV
EELCLAVPTQ GTKYMLNCNC WLAKDRGDGI TSRVFDLLDA MVVNIGVKVL YEMTVWTGDV
VGGGTDSNIF MTLYGINGST EEMQLDKRKF EREQNDTFIM EILDIAPFTK MRIRIDGLGS
RPEWFLERIL LKNMNTGDLT MFYYGDWLSQ RKGKKTLVCE MCAVIDEEEM MEWTSYTVAV
KTSNILGAGS DANVFIIIFG ENGDSGTLAL KQSANWNKFE RNNTDTFNFP DMLSLGHLCK
LRVWHDNKGI FPGWHLSYVD VKDNSRDETF HFQCDCWLSK SEGDGQTVRD FACANNKIHD
ELEETTYEIV IETGNGGETR ENVWLILEGR KNRSKEFLVE NSSRQRAFRK GTTDTFEFDS
IYLGDIASLC VGHLAREDRF IPKRELVWHV KTITITEMEY GNVYFFNCDC LIPLKRKRKY
FKVFEVTKTT ESFASKVQSL VPVKYEVIVT TGYEPGAGTD ANVFVTIFGA NGDTGKRELK
QKMRNLFERG STDRFFLETL ELGELRKVRL EHDSSGYCSG WLVEKVEVTN TSTGVATIFN
CGRWLDKKRG DGLTWRDLFP SV
//
