ID A0A2R8ZN13_PANPA Unreviewed; 1004 AA.
AC A0A2R8ZN13;
DT 20-JUN-2018, integrated into UniProtKB/TrEMBL.
DT 20-JUN-2018, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=Membrane associated guanylate kinase, WW and PDZ domain containing 1 {ECO:0008006|Google:ProtNLM};
OS Pan paniscus (Pygmy chimpanzee) (Bonobo).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pan.
OX NCBI_TaxID=9597 {ECO:0000313|Ensembl:ENSPPAP00000005945.1, ECO:0000313|Proteomes:UP000240080};
RN [1] {ECO:0000313|Ensembl:ENSPPAP00000005945.1, ECO:0000313|Proteomes:UP000240080}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=22722832; DOI=10.1038/nature11128;
RA Prufer K., Munch K., Hellmann I., Akagi K., Miller J.R., Walenz B.,
RA Koren S., Sutton G., Kodira C., Winer R., Knight J.R., Mullikin J.C.,
RA Meader S.J., Ponting C.P., Lunter G., Higashino S., Hobolth A., Dutheil J.,
RA Karakoc E., Alkan C., Sajjadian S., Catacchio C.R., Ventura M.,
RA Marques-Bonet T., Eichler E.E., Andre C., Atencia R., Mugisha L.,
RA Junhold J., Patterson N., Siebauer M., Good J.M., Fischer A., Ptak S.E.,
RA Lachmann M., Symer D.E., Mailund T., Schierup M.H., Andres A.M., Kelso J.,
RA Paabo S.;
RT "The bonobo genome compared with the chimpanzee and human genomes.";
RL Nature 486:527-531(2012).
RN [2] {ECO:0000313|Ensembl:ENSPPAP00000005945.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AJFE02036725; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJFE02036726; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJFE02036727; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A2R8ZN13; -.
DR Ensembl; ENSPPAT00000026413.1; ENSPPAP00000005945.1; ENSPPAG00000023910.1.
DR GeneTree; ENSGT00940000155820; -.
DR Proteomes; UP000240080; Chromosome 3.
DR Bgee; ENSPPAG00000023910; Expressed in testis and 6 other cell types or tissues.
DR CDD; cd00992; PDZ_signaling; 5.
DR CDD; cd00201; WW; 2.
DR Gene3D; 2.20.70.10; -; 2.
DR Gene3D; 2.30.42.10; -; 5.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR036034; PDZ_sf.
DR InterPro; IPR001202; WW_dom.
DR InterPro; IPR036020; WW_dom_sf.
DR PANTHER; PTHR10316; MEMBRANE ASSOCIATED GUANYLATE KINASE-RELATED; 1.
DR PANTHER; PTHR10316:SF12; MEMBRANE-ASSOCIATED GUANYLATE KINASE, WW AND PDZ DOMAIN-CONTAINING PROTEIN 1; 1.
DR Pfam; PF16663; MAGI_u1; 1.
DR Pfam; PF16666; MAGI_u5; 1.
DR Pfam; PF00595; PDZ; 5.
DR Pfam; PF00397; WW; 2.
DR SMART; SM00228; PDZ; 5.
DR SMART; SM00456; WW; 2.
DR SUPFAM; SSF50156; PDZ domain-like; 5.
DR SUPFAM; SSF51045; WW domain; 2.
DR PROSITE; PS50106; PDZ; 5.
DR PROSITE; PS01159; WW_DOMAIN_1; 2.
DR PROSITE; PS50020; WW_DOMAIN_2; 2.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000240080}.
FT DOMAIN 73..106
FT /note="WW"
FT /evidence="ECO:0000259|PROSITE:PS50020"
FT DOMAIN 132..165
FT /note="WW"
FT /evidence="ECO:0000259|PROSITE:PS50020"
FT DOMAIN 220..289
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 391..469
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 589..671
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 746..842
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 900..982
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT REGION 1..42
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 168..211
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 334..373
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 468..580
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 680..735
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 860..891
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 174..195
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 335..349
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 485..514
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 683..730
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1004 AA; 109304 MW; 94FF04EF67CEDBF7 CRC64;
MQNAGIVHAE NEEEDDVPEM NSSFTADSGE QDEHTLQETA LPPVNSSIIA APITDPSQKF
PQYLPLSAED NLGPLPENWE MAYTENGEVY FIDHNTKTTS WLDPRCLNKQ QKPLEECEDD
EGVHTEELDS ELELPAGWEK IEDPVYGIYY VDHINRKTQY ENPVLEAKRK KQLEQQQQQQ
QQQQQQQQQQ HNPEPAREAP LQGKPFFTRN PSELKGKFIH TKLRKSSRGF GFTVVGGDEP
DEFLQIKSLV LDGPAALDGK METGDVIVSV NDTCVLGHTH AQVVKIFQSI PIGASVDLEL
CRGYPLPFDP DDPNTSLVTS VAILDKEPII VNGQETYDSP ASHSSKTGKV NGMKDARPSS
PADAASNSSH GYPNDTVSLA SSIATQPELI TVHIVKGPMG FGFTIADSPG GGGQRVKQIV
DSPRCRGLKE GDLIVEVNKK NVQALTHNQV VDMLVECPKG SEVTLLVQRG GLPVPKKSPK
SQPLERKDSQ NSSQHSVSSH RSLHTASPSH STQVLPEFPP AEAQAPDQTD SSGQKKPDPF
KIWAQSRSMY ENRPMSPSPA SGLSKGERER EINSTNFGEC PIPDYQEQDI FLWRKETGFG
FRILGGNEPG EPIYIGHIVP LGAADTDGRL RSGDELICVD GTPVIGKSHQ LVVQLMQQAA
KQGHVNLTVR RKVVFAVPKT ENEVPSPASS HHSSNQPASL TEEKRTPQGS QNSLNTVSSG
SGSTSGIGSG GGGGSGVVST VVQPYDVEIR RGENEGFGFV IVSSVSRPEA GTTFAGNACV
AMPHKIGRII EGSPADRCGK LKVGDRILAV NGCSITNKSH SDIVNLIKEA GNTVTLRIIP
GDESSNATLL TNAEKIATIT TTHTPSQQGT QETRNTTKPK QESQFEFKAP QATQEQDFYT
VELERGAKGF GFSLRGGREY NMDLYVLRLA EDGPAERCGK MRIGDEILEI NGETTKNMKH
SRAIELIKNG GRRVRLFLKR GDGSVPEYGG SNYENIPSFP GMTP
//
