ID A0A2R8ZP01_PANPA Unreviewed; 2289 AA.
AC A0A2R8ZP01;
DT 20-JUN-2018, integrated into UniProtKB/TrEMBL.
DT 20-JUN-2018, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=DOP1 leucine zipper like protein B {ECO:0000313|Ensembl:ENSPPAP00000006255.1};
GN Name=DOP1B {ECO:0000313|Ensembl:ENSPPAP00000006255.1};
OS Pan paniscus (Pygmy chimpanzee) (Bonobo).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pan.
OX NCBI_TaxID=9597 {ECO:0000313|Ensembl:ENSPPAP00000006255.1, ECO:0000313|Proteomes:UP000240080};
RN [1] {ECO:0000313|Ensembl:ENSPPAP00000006255.1, ECO:0000313|Proteomes:UP000240080}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=22722832; DOI=10.1038/nature11128;
RA Prufer K., Munch K., Hellmann I., Akagi K., Miller J.R., Walenz B.,
RA Koren S., Sutton G., Kodira C., Winer R., Knight J.R., Mullikin J.C.,
RA Meader S.J., Ponting C.P., Lunter G., Higashino S., Hobolth A., Dutheil J.,
RA Karakoc E., Alkan C., Sajjadian S., Catacchio C.R., Ventura M.,
RA Marques-Bonet T., Eichler E.E., Andre C., Atencia R., Mugisha L.,
RA Junhold J., Patterson N., Siebauer M., Good J.M., Fischer A., Ptak S.E.,
RA Lachmann M., Symer D.E., Mailund T., Schierup M.H., Andres A.M., Kelso J.,
RA Paabo S.;
RT "The bonobo genome compared with the chimpanzee and human genomes.";
RL Nature 486:527-531(2012).
RN [2] {ECO:0000313|Ensembl:ENSPPAP00000006255.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the dopey family.
CC {ECO:0000256|ARBA:ARBA00008395}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AJFE02084393; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJFE02084394; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJFE02084395; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJFE02084396; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJFE02084397; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJFE02084398; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJFE02084399; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJFE02084400; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJFE02084401; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJFE02084402; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR Ensembl; ENSPPAT00000027268.1; ENSPPAP00000006255.1; ENSPPAG00000024601.1.
DR GeneTree; ENSGT00390000016421; -.
DR OMA; LWEYMTQ; -.
DR Proteomes; UP000240080; Chromosome 21.
DR Bgee; ENSPPAG00000024601; Expressed in cerebellum and 6 other cell types or tissues.
DR GO; GO:0005829; C:cytosol; IEA:GOC.
DR GO; GO:0006895; P:Golgi to endosome transport; IEA:InterPro.
DR InterPro; IPR040314; DOP1.
DR InterPro; IPR007249; Dopey_N.
DR PANTHER; PTHR14042; DOPEY-RELATED; 1.
DR PANTHER; PTHR14042:SF23; PROTEIN DOPEY-2; 1.
DR Pfam; PF04118; Dopey_N; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000240080};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 12..304
FT /note="Dopey N-terminal"
FT /evidence="ECO:0000259|Pfam:PF04118"
FT REGION 568..589
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 641..677
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 697..718
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1088..1136
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 646..660
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 661..675
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 697..715
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1092..1107
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1108..1130
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2289 AA; 256813 MW; EE482A872917C871 CRC64;
MDPEEQELLN DYRYRSYSSV IEKALRNFES SSEWADLISS LGKLNKALQS NLRYSLLPRR
LLISKRLAQC LHPALPSGVH LKALETYEII FKIVGTKWLA KDLFLYSCGL FPLLAHAAVS
VRPVLLTLYE KYFLPLQKLL LPSLQAFIVG LLPGLEEGSE ISDRTDALLL RLSLVVGKEV
FYTALWGSVL ASPSIRLPAS VFVVGHINRD APGREQKYML GTNHQLTVKS LRASLLDSNV
LVQRNNLEIV LFFFPFYTCL DSNERAIPLL RSDIVRILSA ATQTLLRRDM SLNRRLYAWL
LGSDIKGNTV VPESEISNSY EDQSSYFFEK YSKDLLVEGL AEILHQKFID ADVEERHHAY
LKPFRVLISL LDKPEIGPQV VGNLFLEVIR AFYSYCRDAL GSDLKLSYTQ SGNSLISPPI
SASQSVKIIG ESLHAWPKNG FFFAVIYRPV KQRYSVRNSV SPPPTVSELC TLLVFLLDVI
PLELYSEVQT QYLPQVLGCL VQPLAEDMEA LSLPELTHAL KTCFKVLSKV QMPPSYLDTE
STSGTSSPVK GENGKIILET KAVIPGDEDA SFPPLKSEDS GIGLSASSPE LSEHLRVPRV
SLERDDVWKK GGSMQRTFLC IQELIANFAS KNIFGVQLTA SGEESKSEEP AGKRDRDGTQ
SLAANDSSRK NSWEPKPITV PQFKQMLSDL FTARGSPFKT KSSESPSSSP SSPARKNGGE
WDVEKVVIDL GGSREERREA FAAACHLLLD CATFPVYLSE EETEQLCATL FQLPGAGDCS
FPSWLKSLMT ICCCVTDCYL QNVAISTLLE VINHSQSLAL VIEDKMKRYK SSGHNPFFGK
LQMVTVPPIA PGILKVIAEK TDFYQRVARV LWNQLNKETR EHHVTCVELF YRLHCLAPTA
NICEDIICHA LLDPDKGTRL EALFRFSVIW HLTREIQGSR VTSHNRSFDR SLFVVLDSLA
CTDGAIGAAA QGWLVRALSL GDVARILEPV LLLLLQPKTQ RTSIHCLKQE NSADDLHRWF
NRKKTSFREA CAVPELQESG SEEHLPLSQF TTVDREAIWA EVEKEPEKYP LRGELSEEEL
PYYVELPDRT AHGAPDSSEH TESADTSSGH TDSENTSSFS SPSHDPQELS NEENCCAPIP
MGGRAYPKRS ALLAAFQSES FKAGAKLSLV RVDSDKTQAS ESFSSDEEAD LELQALTTSR
LLKQQRERQE AVEALFKHIL LYLQPYDSRR VLYAFSVLEA VLKTNPKEFI EAVSRTSMDT
SSTAHLNLIS NLLARHQEAL IGQSFYGKLQ TQAPNVCPHS LLLELLTYLC LSFLRSYYPC
YLKVSHRDIL GNRDVQVKSV EVLIRIMMQL VSVAKSSEGK NVEFIHSLLQ RCKVQEFVLL
SLSASMYTSQ KRYGLATAHH GRALPEDSLF EESLINLGQD QICSEHPLQI ELLKLLQVLI
VLEHHLGRAH EEAENQPDLS REWQRALNFQ QAISALQYVQ PHPLTSQGLL VSAVVRGLQP
AYGYGMHPAW VSLVTHSLPY FGKSLGWTVT PFVVQICKNL DDLVKQYESE SVKLSVSTTS
KRENISPDYP LTLLEGLTTI SHFCLLEQAN QNKKTMAAGD PANLRNARNA ILEELPRTVN
TMALLWNVLR KEETQKRPVD LLGATKGSSS VYFKTTKTIR QKILDFLNPL TAHLGVQLTA
AVAAVWSRKK AQRHSKMKII PTASASQLTL VDLVCALSTL QTDTLLHLVK EVVKRPPQVK
GGDEKSPLVD IPVLQFCYAF LQRLPVPALQ ENFSSLLGVL KESVQLNLAP PGYFLLLSML
NDFVTRTPNL ENKKDQKDLQ EITQKILEAV GNIAGSSLEQ TSWLSRNLEV KAQPQASLEE
SDAEEDLYDA AAASAMVSSS APSVYSVQAL SLLAEVLASL LDMVYRSDEK EKAVPLISRL
LYYVFPYLRN HSAYNAPSFR AGAQLLSSLS GYAYTKRAWR KEVLELFLDP AFFQMDTSCV
HWKSIIDHLL THEKTMFKDL MNMQSSSLKL FSSFEQKAML LKRQAFAVFS GELDQYHLYL
PLIQERLTDN LRVGQTSIVA AQMFLFFRVL LLRISPQHLT SLWPIMVSEL IQTFTQLEED
LKDEDESLRS TNKVNRTKVS VPDANGPSVG EIPQSELILY LSACKFLDTA LSFPPDKMPL
FQIYRWAFIP EVDTEGPAFL SDVEENQQEC KPHTVRILEL LKLKFGEISS SDEITMKSEF
PLLRQHSVSS IRQLMPFFMT LNGAFKTQRQ LPADSPGTPF LDFPVTDSPR ILKQLEECIE
YDFLEHPEC
//
