ID A0A2R8ZR05_PANPA Unreviewed; 1182 AA.
AC A0A2R8ZR05;
DT 20-JUN-2018, integrated into UniProtKB/TrEMBL.
DT 20-JUN-2018, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Myelin transcription factor 1 like {ECO:0000313|Ensembl:ENSPPAP00000005266.1};
GN Name=MYT1L {ECO:0000313|Ensembl:ENSPPAP00000005266.1};
OS Pan paniscus (Pygmy chimpanzee) (Bonobo).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pan.
OX NCBI_TaxID=9597 {ECO:0000313|Ensembl:ENSPPAP00000005266.1, ECO:0000313|Proteomes:UP000240080};
RN [1] {ECO:0000313|Ensembl:ENSPPAP00000005266.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the MYT1 family.
CC {ECO:0000256|ARBA:ARBA00010194}.
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DR EMBL; AJFE02021503; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJFE02021504; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJFE02021505; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJFE02021506; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJFE02021507; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJFE02021508; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJFE02021509; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A2R8ZR05; -.
DR Ensembl; ENSPPAT00000024023.1; ENSPPAP00000005266.1; ENSPPAG00000021774.1.
DR GeneTree; ENSGT00940000155671; -.
DR Proteomes; UP000240080; Unplaced.
DR Bgee; ENSPPAG00000021774; Expressed in prefrontal cortex and 3 other cell types or tissues.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR GO; GO:0007399; P:nervous system development; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR Gene3D; 4.10.320.30; -; 6.
DR InterPro; IPR013681; Myelin_TF.
DR InterPro; IPR002515; Znf_C2H2C.
DR InterPro; IPR036060; Znf_C2H2C_sf.
DR PANTHER; PTHR10816:SF11; MYELIN TRANSCRIPTION FACTOR 1-LIKE PROTEIN; 1.
DR PANTHER; PTHR10816; MYELIN TRANSCRIPTION FACTOR 1-RELATED; 1.
DR Pfam; PF08474; MYT1; 1.
DR Pfam; PF01530; zf-C2HC; 6.
DR SUPFAM; SSF103637; CCHHC domain; 6.
DR PROSITE; PS51802; ZF_CCHHC; 6.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000240080};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU01143}.
FT DOMAIN 617..868
FT /note="Myelin transcription factor 1"
FT /evidence="ECO:0000259|Pfam:PF08474"
FT REGION 1..20
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 54..171
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 216..243
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 338..368
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 445..509
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 655..705
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 749..776
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 1054..1123
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 87..165
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 338..354
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 445..503
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 680..705
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1182 AA; 132476 MW; 3EE674D69BFFF168 CRC64;
MEVDTEEKRH RTRSKGVRGM SVLPCILSCP TPGCDGSGHV SGKYARHRSV YGCPLAKKRK
TQDKQPQEPA PKRKPFAVKA DSSSVDECDD SDGTEDMDEK EEDEGEEYSE DNDEPGDEDE
EDEEGDREEE EEIEEEDEDD DEDGEDVEDE EEEEEEEEEE EEENEDHQMN CHNTRIMQDT
EKDDNNNDEY DNYDELVAKS LLNLGKIAED AAYRARTESE MNSNTSNSLE DDSDKNENLG
RKSELSLDLD SDVVRETVDS LKLLAQGHGV VLSENMNDRN YADSMSQQDS RNMNYVMLGK
PMNNGLMEKM VEESDEEVCL SSLECLRNQC FDLARKLSET NPQERNPQQN MNIRQHVRPE
EDFPGRTPDR NYSDMLNLMR LEEQLSPRSR VFASCAKEDG CHERDDDTTS VNSDRSEEVF
DMTKGNLTLL EKAIALETER AKAMREKMAM EAGRRDNMRS YEDQSPRQLP GEDRKPKSSD
SHVKKPYYGK DPSRTEKKES KCPTPGCDGT GHVTGLYPHH RSLSGCPHKD RVPPEILAMH
ESVLKCPTPG CTGRGHVNSN RNSHRSLSGC PIAAAEKLAK AQEKHQSCDV SKSSQASDRV
LRPMCFVKQL EIPQYGYRNN VPTTTPRSNL AKELEKYSKT SFEYNSYDNH TYGKRAIAPK
VQTRDISPKG YDDAKRYCKD PSPSSSSTSS YAPSSSSNLS CGGGSSASST CSKSSFDYTH
DMEAAHMAAT AILNLSTRCR EMPQNLSTKP QDLCATRNPD MEVDENGTLD LSMNKQRPRD
SCCPILTPLE PMSPQQQAVM NNRCFQLGEG DCWDLPVDYT KMKPRRIDED ESKDITPEDL
DPFQEALEER RYPGEVTIPS PKPKYPQCKE SKKDLITLSG CPLADKSIRS MLATSSQELK
CPTPGCDGSG HITGNYASHR SLSGCPRAKK SGIRIAQSKE DKEDQEPIRC PVPGCDGQGH
ITGKYASHRS ASGCPLAAKR QKDGYLNGSQ FSWKSVKTEG MSCPTPGCDG SGHVSGSFLT
HRSLSGCPRA TSAMKKAKLS GEQMLTIKQR ASNGIENDEE IKQLDEEIKE LNESNSQMEA
DMIKLRTQIT TMESNLKTIE EENKVIEQQN ESLLHELANL SQSLIHSLAN IQLPHMDPIN
EQNFDAYVTT LTEMYTNQDR YQSPENKALL ENIKQAVRGI QV
//
