ID A0A2R8ZXD4_PANPA Unreviewed; 502 AA.
AC A0A2R8ZXD4;
DT 20-JUN-2018, integrated into UniProtKB/TrEMBL.
DT 20-JUN-2018, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=Zinc finger CCCH-type with G patch domain-containing protein {ECO:0000256|ARBA:ARBA00022414};
GN Name=ZGPAT {ECO:0000313|Ensembl:ENSPPAP00000009226.1};
OS Pan paniscus (Pygmy chimpanzee) (Bonobo).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pan.
OX NCBI_TaxID=9597 {ECO:0000313|Ensembl:ENSPPAP00000009226.1, ECO:0000313|Proteomes:UP000240080};
RN [1] {ECO:0000313|Ensembl:ENSPPAP00000009226.1, ECO:0000313|Proteomes:UP000240080}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=22722832; DOI=10.1038/nature11128;
RA Prufer K., Munch K., Hellmann I., Akagi K., Miller J.R., Walenz B.,
RA Koren S., Sutton G., Kodira C., Winer R., Knight J.R., Mullikin J.C.,
RA Meader S.J., Ponting C.P., Lunter G., Higashino S., Hobolth A., Dutheil J.,
RA Karakoc E., Alkan C., Sajjadian S., Catacchio C.R., Ventura M.,
RA Marques-Bonet T., Eichler E.E., Andre C., Atencia R., Mugisha L.,
RA Junhold J., Patterson N., Siebauer M., Good J.M., Fischer A., Ptak S.E.,
RA Lachmann M., Symer D.E., Mailund T., Schierup M.H., Andres A.M., Kelso J.,
RA Paabo S.;
RT "The bonobo genome compared with the chimpanzee and human genomes.";
RL Nature 486:527-531(2012).
RN [2] {ECO:0000313|Ensembl:ENSPPAP00000009226.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBUNIT: Interacts with CHD4/Mi-2; the interaction is direct.
CC {ECO:0000256|ARBA:ARBA00011506}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; AJFE02030792; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJFE02030793; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJFE02030794; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJFE02030795; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJFE02030796; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJFE02030797; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJFE02030798; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJFE02030799; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJFE02030800; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_008960537.1; XM_008962289.1.
DR AlphaFoldDB; A0A2R8ZXD4; -.
DR Ensembl; ENSPPAT00000031866.1; ENSPPAP00000009226.1; ENSPPAG00000027831.1.
DR GeneID; 100975955; -.
DR CTD; 84619; -.
DR GeneTree; ENSGT00390000000732; -.
DR OrthoDB; 3060898at2759; -.
DR Proteomes; UP000240080; Chromosome 20.
DR Bgee; ENSPPAG00000027831; Expressed in liver and 6 other cell types or tissues.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd20384; Tudor_ZGPAT; 1.
DR Gene3D; 2.30.30.1190; -; 1.
DR Gene3D; 2.30.30.140; -; 1.
DR InterPro; IPR000467; G_patch_dom.
DR InterPro; IPR041367; Znf-CCCH_4.
DR InterPro; IPR000571; Znf_CCCH.
DR InterPro; IPR036855; Znf_CCCH_sf.
DR PANTHER; PTHR46297; ZINC FINGER CCCH-TYPE WITH G PATCH DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR46297:SF1; ZINC FINGER CCCH-TYPE WITH G PATCH DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF01585; G-patch; 1.
DR Pfam; PF18044; zf-CCCH_4; 1.
DR SMART; SM00443; G_patch; 1.
DR SMART; SM00356; ZnF_C3H1; 1.
DR SUPFAM; SSF90229; CCCH zinc finger; 1.
DR SUPFAM; SSF63748; Tudor/PWWP/MBT; 1.
DR PROSITE; PS50174; G_PATCH; 1.
DR PROSITE; PS50103; ZF_C3H1; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723, ECO:0000256|PROSITE-
KW ProRule:PRU00723}; Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000240080};
KW Repressor {ECO:0000256|ARBA:ARBA00022491};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|PROSITE-ProRule:PRU00723};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00723}.
FT DOMAIN 175..201
FT /note="C3H1-type"
FT /evidence="ECO:0000259|PROSITE:PS50103"
FT DOMAIN 304..350
FT /note="G-patch"
FT /evidence="ECO:0000259|PROSITE:PS50174"
FT ZN_FING 175..201
FT /note="C3H1-type"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00723"
FT REGION 91..133
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 356..380
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 397..417
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 480..502
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 487..502
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 502 AA; 54717 MW; DE6626E060A8340D CRC64;
MDEESLESAL QTYRAQLQQV ELALGAGLDS SEQADLRQLQ GDLKELIELT EASLVSVRKS
RLLAALDEER PGRQEDAEYQ DFREAITEAV QAPAAARGSG SETVPKAEAG PESAAGGQEE
EEGEDEEELS GTKVSAPYYS SWGTLEYHNA MVVGTEEAED GSAGVRVLYL YPTHKSLKPC
PFFLEGKCRF KENCRFSHGQ VVSLDELRPF QDPDLSSLQA GSACLAKHQD GLWHAARITD
VDNGYYTVKF DSLLLREAVV EGDGILPPLR TEATESDSDS DVVGSDAVDS GTCSSAFAGW
EVHTRGIGSR LLTKMGYEFG KGLGRHAEGR VEPIHAVVLP RGKSLDQCVE TLQKQTRVGK
AGTNKPPRCR GRGARPGGRP APRNVFDFLN EKLQGQAPGA LEAGAAPAGR RSKDMYHASK
SAKRALSLRL FQTEEKIERT QRDIRSIQEA LARNAGRHSV ASAQLQEKLA GAQRQLGQLR
AQEAGLQQEQ RKADTHKKMT EF
//
